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  1. Buch: High content screening

    Johnston, Paul A. / Trask, Oscar J.

    a powerful approach to systems cell biology and phenotypic drug discovery

    (Methods in molecular biology ; 1683 ; Springer protocols ; Chemistry)

    2018  

    Verfasserangabe edited by Paul A. Johnston (Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA), Oscar J. Trask (Bahama Bio, LLC, Bahama, NC, USA; Perkin Elmer Inc., Waltham, MA, USA)
    Serientitel Methods in molecular biology ; 1683
    Springer protocols
    Chemistry
    Überordnung
    Schlagwörter measure cells ; cell phenotypes ; HCS data ; data handling ; HCS/HCA/HCI
    Thema/Rubrik (Code) 570
    Sprache Englisch
    Umfang xiii, 397 Seiten, Illustrationen, 25.4 cm x 17.8 cm
    Ausgabenhinweis Second edition
    Verlag Humana Press
    Erscheinungsort New York, NY
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT019509018
    ISBN 978-1-4939-7355-2 ; 1-4939-7355-X ; 9781493973576 ; 1493973576
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Artikel ; Online: UK Field Medical Care 2032: one Military Vision.

    Parker, Paul / Pynn, H / Haldane, A G / Ballard, M / König, T C / Johnston, A M

    BMJ military health

    2023  Band 169, Heft 6, Seite(n) 485–487

    Mesh-Begriff(e) Humans ; Military Personnel ; Military Medicine ; Emergency Medical Services ; United Kingdom
    Sprache Englisch
    Erscheinungsdatum 2023-11-22
    Erscheinungsland England
    Dokumenttyp Editorial
    ZDB-ID 3011686-7
    ISSN 2633-3775 ; 2633-3767
    ISSN (online) 2633-3775
    ISSN 2633-3767
    DOI 10.1136/bmjmilitary-2021-002056
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: WITHDRAWN: Detection and impact of hypoxic regions in multicellular tumor spheroid cultures formed by head and neck squamous cell carcinoma cells lines.

    Close, David A / Johnston, Paul A

    SLAS discovery : advancing life sciences R & D

    2023  Band 29, Heft 1F, Seite(n) 130

    Sprache Englisch
    Erscheinungsdatum 2023-12-13
    Erscheinungsland United States
    Dokumenttyp Retraction of Publication
    ZDB-ID 2885123-7
    ISSN 2472-5560 ; 2472-5552
    ISSN (online) 2472-5560
    ISSN 2472-5552
    DOI 10.1016/j.slasd.2023.12.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Chitin and Chitosan Binding to the α-Chitin Crystal: A Molecular Dynamics Study.

    Hudek, Magdalena / Kubiak-Ossowska, Karina / Johnston, Karen / Ferro, Valerie A / Mulheran, Paul A

    ACS omega

    2023  Band 8, Heft 3, Seite(n) 3470–3477

    Abstract: Understanding the binding of chitosan oligomers to the surface of a chitin nanocrystal is important for improving the enzymatic deacetylation of chitin and for the design of chitin/chitosan composite films. Here, we study the binding of several chito- ... ...

    Abstract Understanding the binding of chitosan oligomers to the surface of a chitin nanocrystal is important for improving the enzymatic deacetylation of chitin and for the design of chitin/chitosan composite films. Here, we study the binding of several chito-oligomers to the (100) surface of an α-chitin crystal using molecular dynamics (MD), steered MD, and umbrella sampling. The convergence of the free energy was carefully considered and yielded a binding energies of -12.5 and -2 kcal mol
    Sprache Englisch
    Erscheinungsdatum 2023-01-10
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c07495
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Buch ; Konferenzbeitrag: Changing concepts for the efficient use of phosphorus in agriculture

    Johnston, A. E. / Poulton, Paul R.

    paper presented to the International Fertiliser Society at a conference in Cambridge, UK, on 11th December 2014

    (Proceedings / International Fertiliser Society ; 757)

    2014  

    Verfasserangabe by A. E. Johnston and P. R. Poulton
    Serientitel Proceedings / International Fertiliser Society ; 757
    Proceedings / the International Fertiliser Society
    Überordnung Proceedings / the International Fertiliser Society
    Schlagwörter Phosphatic fertilizers ; Fertilizers/Application ; Soils/Phosphorus content ; Phosphorus/Bioavailability ; Soil fertility
    Thema/Rubrik (Code) 631.85
    Sprache Englisch
    Umfang 40 S. : graph. Darst.
    Erscheinungsort Colchester
    Erscheinungsland Vereinigtes Königreich
    Dokumenttyp Buch ; Konferenzbeitrag
    HBZ-ID HT018603251
    ISBN 978-0-85310-394-3 ; 0-85310-394-1
    Datenquelle Katalog ZB MED Ernährung, Umwelt, Agrar

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  6. Artikel ; Online: Organic enrichment reduces sediment bacterial and archaeal diversity, composition, and functional profile independent of bioturbator activity.

    Gonzalez, Sebastian Vadillo / Dafforn, Katherine A / Gribben, Paul E / O'Connor, Wayne A / Johnston, Emma L

    Marine pollution bulletin

    2023  Band 196, Seite(n) 115608

    Abstract: Eutrophication is a worldwide issue that can disrupt ecosystem processes in sediments. Studies have shown that macrofauna influences sediment processes by engineering environments that constrain microbial communities. Here, we explored the effect of ... ...

    Abstract Eutrophication is a worldwide issue that can disrupt ecosystem processes in sediments. Studies have shown that macrofauna influences sediment processes by engineering environments that constrain microbial communities. Here, we explored the effect of different sizes of the Sydney cockle (Anadara trapezia), on bacterial and archaeal communities in natural and experimentally enriched sediments. A mesocosm experiment was conducted with two enrichment conditions (natural or enriched) and 5 cockle treatments (small, medium, large, mixed sizes and a control). This study was unable to detect A. trapezia effects on microbial communities irrespective of body size. However, a substantial decrease of bacterial richness, diversity, and structural and functional shifts, were seen with organic enrichment of sediments. Archaea were similarly changed although the magnitude of effect was less than for bacteria. Overall, we found evidence to suggest that A. trapezia had limited capacity to affect sediment microbial communities and mitigate the effects of organic enrichment.
    Mesh-Begriff(e) Animals ; Archaea/genetics ; Geologic Sediments/chemistry ; Bacteria/genetics ; Microbiota ; Arcidae ; RNA, Ribosomal, 16S
    Chemische Substanzen RNA, Ribosomal, 16S
    Sprache Englisch
    Erscheinungsdatum 2023-10-03
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2001296-2
    ISSN 1879-3363 ; 0025-326X
    ISSN (online) 1879-3363
    ISSN 0025-326X
    DOI 10.1016/j.marpolbul.2023.115608
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Incorporating Measures of Sustainability Into Guideline Development.

    Ashley, Paul / Lyne, Alexandra / Johnston, Bridget / Duane, Brett

    International dental journal

    2023  Band 73, Heft 6, Seite(n) 800–803

    Sprache Englisch
    Erscheinungsdatum 2023-09-23
    Erscheinungsland England
    Dokumenttyp Editorial
    ZDB-ID 218262-2
    ISSN 1875-595X ; 0020-6539
    ISSN (online) 1875-595X
    ISSN 0020-6539
    DOI 10.1016/j.identj.2023.05.006
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Detection and impact of hypoxic regions in multicellular tumor spheroid cultures formed by head and neck squamous cell carcinoma cells lines.

    Close, David A / Johnston, Paul A

    SLAS discovery : advancing life sciences R & D

    2021  Band 27, Heft 1, Seite(n) 39–54

    Abstract: In solid tumors like head and neck cancer (HNC), chronic and acute hypoxia have serious adverse clinical consequences including poorer overall patient prognosis, enhanced metastasis, increased genomic instability, and resistance to radiation-, chemo-, or ...

    Abstract In solid tumors like head and neck cancer (HNC), chronic and acute hypoxia have serious adverse clinical consequences including poorer overall patient prognosis, enhanced metastasis, increased genomic instability, and resistance to radiation-, chemo-, or immuno-therapies. However, cells in the two-dimensional monolayer cultures typically used for cancer drug discovery experience 20%-21% O
    Mesh-Begriff(e) Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Head and Neck Neoplasms/drug therapy ; Head and Neck Neoplasms/genetics ; Humans ; Hypoxia/drug therapy ; Spheroids, Cellular ; Squamous Cell Carcinoma of Head and Neck/drug therapy ; Squamous Cell Carcinoma of Head and Neck/genetics ; Tumor Microenvironment
    Chemische Substanzen Antineoplastic Agents
    Sprache Englisch
    Erscheinungsdatum 2021-10-13
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2885123-7
    ISSN 2472-5560 ; 2472-5552
    ISSN (online) 2472-5560
    ISSN 2472-5552
    DOI 10.1016/j.slasd.2021.10.008
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Battlefield REBOA: Aces High or Journey's End?

    Parker, Paul / Johnston, A M / Mountain, A / Pynn, H

    BMJ military health

    2023  Band 169, Heft 6, Seite(n) 482–484

    Sprache Englisch
    Erscheinungsdatum 2023-11-22
    Erscheinungsland England
    Dokumenttyp Editorial
    ZDB-ID 3011686-7
    ISSN 2633-3775 ; 2633-3767
    ISSN (online) 2633-3775
    ISSN 2633-3767
    DOI 10.1136/bmjmilitary-2021-002054
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Buch ; Konferenzbeitrag: Nitrogen in agriculture

    Johnston, A. E. / Poulton, Paul R.

    an overview and definitions of nitrogen use efficiency ; paper presented to The International Fertiliser Society at a Conference in Cambridge, on 9th December 2009

    (Proceedings / International Fertiliser Society ; 651)

    2009  

    Verfasserangabe by A. E. Johnston and P. R. Poulton
    Serientitel Proceedings / International Fertiliser Society ; 651
    Proceedings / the International Fertiliser Society
    Überordnung Proceedings / the International Fertiliser Society
    Sprache Englisch
    Umfang 48 S. : graph. Darst.
    Verlag Internat. Fert. Soc
    Erscheinungsort York
    Erscheinungsland Vereinigtes Königreich
    Dokumenttyp Buch ; Konferenzbeitrag
    HBZ-ID HT016246606
    ISBN 978-0-85310-288-5 ; 0-85310-288-0
    Datenquelle Katalog ZB MED Ernährung, Umwelt, Agrar

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