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  1. Artikel ; Online: Dietary Fiber in Inflammatory Bowel Disease: Are We Ready to Change the Paradigm?

    Loy, Laura / Petronio, Lorenzo / Marcozzi, Giacomo / Bezzio, Cristina / Armuzzi, Alessandro

    Nutrients

    2024  Band 16, Heft 8

    Abstract: Accumulating evidence from pre-clinical and clinical studies demonstrate the benefit of dietary fibers for inflammatory bowel disease (IBD). However, the majority of patients avoid or limit their consumption to manage their symptoms during the active and ...

    Abstract Accumulating evidence from pre-clinical and clinical studies demonstrate the benefit of dietary fibers for inflammatory bowel disease (IBD). However, the majority of patients avoid or limit their consumption to manage their symptoms during the active and remission phases, although limited research supports these long-term dietary habits. Although recent evidence-based dietary guidelines highlight the importance of promoting an adequate intake of dietary fiber in IBD patients, intervention trials have not yet clearly clarified the quality and quantity of dietary fiber that should be consumed to be equally tolerated by and provide benefit for patients with IBD. This narrative review describes dietary fibers and their characteristics, analyzes the real-word studies on the impact of dietary fiber consumption in IBD in different clinical settings, and concludes with potential future directions in fiber research, focusing on the real-world needs of characterizing the consumption of fiber-rich foods and promoting their adequate intake.
    Mesh-Begriff(e) Dietary Fiber/administration & dosage ; Humans ; Inflammatory Bowel Diseases/diet therapy ; Diet
    Chemische Substanzen Dietary Fiber
    Sprache Englisch
    Erscheinungsdatum 2024-04-10
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu16081108
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Letter: immune-mediated inflammatory diseases and inflammatory bowel disease-are we ready for a Copernican revolution?

    Bezzio, Cristina / Alimenti, Eleonora / Saibeni, Simone

    Alimentary pharmacology & therapeutics

    2022  Band 56, Heft 9, Seite(n) 1429–1430

    Mesh-Begriff(e) Chronic Disease ; Humans ; Inflammatory Bowel Diseases/drug therapy
    Sprache Englisch
    Erscheinungsdatum 2022-10-11
    Erscheinungsland England
    Dokumenttyp Letter ; Comment
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/apt.17235
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Severe Inflammatory Bowel Disease Flares and COVID-19: Expand the Gastroenterology-Surgery Team to Include an Infectious Disease Specialist.

    Bezzio, Cristina / Saibeni, Simone

    Gastroenterology

    2020  Band 160, Heft 7, Seite(n) 2625–2626

    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-06-16
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2020.05.082
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Prevalence and Clinical Impact of Immune-Mediated Inflammatory Diseases in Patients with Inflammatory Bowel Disease: Results from a Large Retrospective Observational Study.

    Vernero, Marta / Saibeni, Simone / Scalvini, Davide / Cicalini, Carolina / Chiarello, Lorenzo / Nardi, Silvia / Ribaldone, Davide Giuseppe / Bezzio, Cristina

    Journal of clinical medicine

    2024  Band 13, Heft 4

    Abstract: 1) Background: ...

    Abstract (1) Background:
    Sprache Englisch
    Erscheinungsdatum 2024-02-09
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13041019
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Cancer Risk in Patients Treated with the JAK Inhibitor Tofacitinib: Systematic Review and Meta-Analysis.

    Bezzio, Cristina / Vernero, Marta / Ribaldone, Davide Giuseppe / Alimenti, Eleonora / Manes, Gianpiero / Saibeni, Simone

    Cancers

    2023  Band 15, Heft 8

    Abstract: Tofacitinib is approved for several immune-mediated inflammatory diseases, but safety concerns have recently been raised. We searched PubMed (accessed on 27 February 2023) for original articles regarding tofacitinib's cancer risk when used for rheumatoid ...

    Abstract Tofacitinib is approved for several immune-mediated inflammatory diseases, but safety concerns have recently been raised. We searched PubMed (accessed on 27 February 2023) for original articles regarding tofacitinib's cancer risk when used for rheumatoid arthritis, ulcerative colitis, Crohn's disease, psoriatic arthritis, and ankylosing spondylitis. Of the 2047 initial records, 22 articles describing 26 controlled studies (including 22 randomized controlled trials) were selected. In the comparison between tofacitinib and any control treatment, the relative risk (RR) for any cancer was 1.06 (95% CI, 0.86-1.31;
    Sprache Englisch
    Erscheinungsdatum 2023-04-07
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers15082197
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Gastrointestinal ultrasound in inflammatory bowel disease: Seeing beyond limits.

    Bezzio, Cristina / Saibeni, Simone

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2019  Band 52, Heft 1, Seite(n) 19–20

    Mesh-Begriff(e) Humans ; Inflammatory Bowel Diseases ; Intestines ; Ultrasonography
    Sprache Englisch
    Erscheinungsdatum 2019-11-28
    Erscheinungsland Netherlands
    Dokumenttyp Editorial ; Comment
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2019.11.007
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Ophthalmological Manifestations in Inflammatory Bowel Diseases: Keep an Eye on It.

    Migliorisi, Giulia / Vella, Giovanna / Dal Buono, Arianna / Gabbiadini, Roberto / Busacca, Anita / Loy, Laura / Bezzio, Cristina / Vinciguerra, Paolo / Armuzzi, Alessandro

    Cells

    2024  Band 13, Heft 2

    Abstract: Background and aims: Inflammatory bowel diseases (IBD) are multifactorial chronic inflammatory disorders affecting the gastrointestinal tract. However, a broad spectrum of extraintestinal manifestations (EIMs) is associated with IBD, affecting several ... ...

    Abstract Background and aims: Inflammatory bowel diseases (IBD) are multifactorial chronic inflammatory disorders affecting the gastrointestinal tract. However, a broad spectrum of extraintestinal manifestations (EIMs) is associated with IBD, affecting several organs and systems, such as the skin, musculoskeletal and hepatobiliary systems, and, not least, the eye. Approximately 10% of IBD patients can develop ocular EIMs (O-EIMs) with a higher prevalence in Crohn's disease (CD). Eye-redness, photophobia, pain, and blurred vision are the common symptoms, with a wide rate of severity and clinical impact on the quality of life. This narrative review aims to summarize the prevalence, pathogenesis, and current evidence-based management of O-EIMs, underlying the importance of a holistic approach and specialties collaboration for a prompt diagnosis and treatment.
    Methods: PubMed was searched up to December 2023 to identify relevant studies investigating the pathogenesis, epidemiology, and treatment of O-EIMs in IBD patients.
    Results: The mechanisms underlying O-EIMs are partially unknown, encompassing immune dysregulation, shared antigens between the eye and the gut, genetic predisposition, and systemic inflammation driven by high levels of interleukins and cytokines in IBD patients. The complexity of O-EIMs' pathogenesis reflects in the management of these conditions, varying from topical and systemic steroids to immunomodulatory molecules and biologic therapy, such as anti-tumor necrosis factor (TNF)-alpha. A multidisciplinary approach is the backbone of the management of O-EIMs.
    Mesh-Begriff(e) Humans ; Quality of Life ; Eye ; Face ; Inflammatory Bowel Diseases ; Crohn Disease
    Sprache Englisch
    Erscheinungsdatum 2024-01-12
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells13020142
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: SEVERE IBD FLARES AND COVID-19

    Bezzio, Cristina / Saibeni, Simone

    Gastroenterology ; ISSN 0016-5085

    EXPAND THE GASTROENTEROLOGY-SURGERY TEAM TO INCLUDE AN INFECTIOUS DISEASE SPECIALIST

    2020  

    Schlagwörter Gastroenterology ; covid19
    Sprache Englisch
    Verlag Elsevier BV
    Erscheinungsland us
    Dokumenttyp Artikel ; Online
    DOI 10.1053/j.gastro.2020.05.082
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel: Inflammatory bowel disease and immune-mediated inflammatory diseases: looking at the less frequent associations.

    Bezzio, Cristina / Della Corte, Cristina / Vernero, Marta / Di Luna, Imma / Manes, Gianpiero / Saibeni, Simone

    Therapeutic advances in gastroenterology

    2022  Band 15, Seite(n) 17562848221115312

    Abstract: Patients with inflammatory bowel disease (IBD) often have other immune-mediated inflammatory diseases (IMIDs), and the prevalence of any IMID is higher in IBD patients than in the general population. IBD and other IMIDs involve alterations in innate and ... ...

    Abstract Patients with inflammatory bowel disease (IBD) often have other immune-mediated inflammatory diseases (IMIDs), and the prevalence of any IMID is higher in IBD patients than in the general population. IBD and other IMIDs involve alterations in innate and adaptive immune responses. Their co-occurrence depends on shared immune and inflammatory processes, pathogenic mechanisms, and genetic and environmental risk factors, including drugs, especially tumor necrosis factor inhibitors. The more common IMIDs associated with IBD have been widely described, so this review focuses on the less frequent associations. The IMIDs discussed here are skin disorders (psoriasis, atopic dermatitis, vitiligo, epidermolysis bullosa acquisita, cutaneous polyarteritis nodosa, and hidradenitis suppurativa), hepato-pancreatic diseases (autoimmune hepatitis, granulomatous hepatitis, and autoimmune pancreatitis), endocrine diseases (autoimmune thyroid diseases, and type 1 diabetes mellitus), multiple sclerosis, and respiratory diseases (asthma, bronchiectasis, and interstitial pneumonia). The early detection of IMIDs in IBD patients is important to prevent their deleterious clinical course and limit their psychological impact. Care for IBD patients with IMIDs should be multispecialist, with a single therapeutic strategy instead of treating each disease separately.
    Sprache Englisch
    Erscheinungsdatum 2022-07-28
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2440710-0
    ISSN 1756-2848 ; 1756-283X
    ISSN (online) 1756-2848
    ISSN 1756-283X
    DOI 10.1177/17562848221115312
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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