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  1. Artikel ; Online: Dr. Yang Zhong: An explorer on the road forever.

    Chen, Fan / Lu, Bao-Rong / Crabbe, James C / Zhao, Jia-Yuan / Zhong, Bo-Jian / Geng, Yu-Peng / Zheng, Yu-Fang / Wang, Hong-Yan

    Protein & cell

    2017  Band 9, Heft 2, Seite(n) 141–144

    Mesh-Begriff(e) Botany/history ; China ; History, 20th Century ; History, 21st Century
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2017-12-11
    Erscheinungsland Germany
    Dokumenttyp Biography ; Historical Article ; Journal Article ; Portrait
    ZDB-ID 2543451-2
    ISSN 1674-8018 ; 1674-800X
    ISSN (online) 1674-8018
    ISSN 1674-800X
    DOI 10.1007/s13238-017-0496-1
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Buch: Zhong yao

    Zheng, Jinsheng

    (Tu shuo Zhong yi)

    2011  

    Verfasserangabe Zheng Jinsheng zhu
    Serientitel Tu shuo Zhong yi
    Mesh-Begriff(e) Materia Medica/history ; Medicine, Chinese Traditional/history
    Schlagwörter China
    Sprache Chinesisch
    Umfang 145 p. :, ill.
    Ausgabenhinweis Di 1 ban.
    Verlag Ren min wei sheng chu ban she
    Erscheinungsort Beijing
    Dokumenttyp Buch
    ISBN 9787117144834 ; 7117144831
    Datenquelle Katalog der US National Library of Medicine (NLM)

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  3. Artikel ; Online: Herbal medicine teng-long-bu-zhong-tang inhibits the growth of human RKO colorectal cancer by regulating apoptosis, senescence, and angiogenesis

    Meng-Meng Wei / Shuang-Shuang Wang / Jia-Lu Zheng / Lei Chen / Xiao Peng / Jin-Fang Chen / Hong-Mei An / Bing Hu

    World Journal of Traditional Chinese Medicine, Vol 8, Iss 1, Pp 110-

    2022  Band 114

    Abstract: Background: Teng-Long-Bu-Zhong-Tang (TLBZT) is a traditional Chinese herbal medicine used to treat ...

    Abstract Background: Teng-Long-Bu-Zhong-Tang (TLBZT) is a traditional Chinese herbal medicine used to treat colorectal cancer (CRC). In the present study, we observed the anti-cancer effects of TLBZT on human RKO CRC. Materials and Methods: Mice were subcutaneously transplanted with RKO cells, divided into control, 5-Fu-administered, TLBZT-administered, and TLBZT and 5-Fu combination-administered groups, and treated with 5-Fluorouracil (5-Fu) and/or TLBZT. Apoptosis was detected by TdT-mediated dUTP nick-end labeling assay. The activity of caspase-3,-8, and-9 was detected using specific commercial kits. Cell senescence was assessed using senescence β-galactosidase staining. Protein expression was evaluated by immunohistochemistry. Results: TLBZT inhibited RKO CRC tumor growth, enhanced the anti-cancer effects of 5-Fu, induced apoptosis, and activated caspase-3,-8, and-9. TLBZT induced cell senescence accompanied by the downregulation of cyclin E1 and cyclin-dependent kinase 2 expressions. TLBZT also inhibited angiogenesis and the expression of hypoxia-inducible factor 1 subunit alpha and vascular endothelial growth factor-A. Conclusions: TLBZT inhibited RKO CRC tumor growth and enhanced the anti-cancer effects of 5-Fu, and it could be associated with apoptosis and cell senescence induction, and angiogenesis inhibition.
    Schlagwörter angiogenesis ; apoptosis ; cell senescence ; chinese herbal medicine ; colorectal cancer ; Medicine (General) ; R5-920
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2022-01-01T00:00:00Z
    Verlag Wolters Kluwer Medknow Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Du-Zhong (Eucommia ulmoides Oliv.) Cortex Extract Alleviates Lead Acetate-Induced Bone Loss in Rats.

    Qi, Shanshan / Zheng, Hongxing / Chen, Chen / Jiang, Hai

    Biological trace element research

    2018  Band 187, Heft 1, Seite(n) 172–180

    Abstract: The purpose of this study was to evaluate the protective effect of Du-Zhong cortex extract (DZCE ... however, this decrease was inhibited by the intake of Du-Zhong cortex extract (P < 0.05, vs. PbAc group; P > 0.05, vs ... The results above indicate that the Du-Zhong cortex extract has protective effects on both stimulation ...

    Abstract The purpose of this study was to evaluate the protective effect of Du-Zhong cortex extract (DZCE) on lead acetate-induced bone loss in rats. Forty female Sprague-Dawley rats were randomly divided into four groups: group I (control) was provided with distilled water. Group II (PbAc) received 500 ppm lead acetate in drinking water for 60 days. Group III (PbAc+DZCE) received 500 ppm lead acetate in drinking water, and given intragastric DZCE (100 mg/kg body weight) for 60 days. Group IV (DZCE) was given intragastric DZCE (100 mg/kg body weight) for 60 days. The bone mineral density, serum biochemical markers, bone histomorphology, and bone marrow adipocyte parameters were analyzed using dual-energy X-ray absorptiometry, biochemistry, histomorphometry, and histopathology, respectively. The results showed that the lumbar spine and femur bone mineral density was significantly decreased in PbAc group compared with the control (P < 0.05); however, this decrease was inhibited by the intake of Du-Zhong cortex extract (P < 0.05, vs. PbAc group; P > 0.05, vs. control and DZCE group). Serum calcium and serum phosphorus in the PbAc+DZCE group were greater than that in the PbAc group (P < 0.05). The PbAc group had higher ALP, osteocalcin, and RANKL than the control group (P < 0.01), and they were significantly lower in the PbAc+DZCE group compared with the PbAc group. There were no significant differences of ALP, osteocalcin, and RANKL among the PbAc+DZCE, control, and DZCE groups (P > 0.05). Serum OPG and OPG/RANKL ration were significantly higher in the PbAc+DZCE group than that in the PbAc group (P < 0.05). The bone histomorphometric analyses showed that bone volume and trabecular thickness in the femoral trabecular bone were significantly lower in the PbAc group than that in the control group, but those were restored in the PbAc+DZCE groups. The bone marrow adipocyte number, percent adipocyte volume per tissue volume (AV/TV), and mean adipocyte diameter were significantly increased in the PbAc group compared to the control (P < 0.01), and those were restored in the PbAc+DZCE group. The differences of those parameters between PbAc+DZCE, DZCE, and the control group were not significant. The results above indicate that the Du-Zhong cortex extract has protective effects on both stimulation of bone formation and suppression of bone resorption in lead-exposed rats, therefore, Du-Zhong cortex extract has the potential to prevent or treat osteoporosis resulting from lead expose.
    Mesh-Begriff(e) Adipocytes/drug effects ; Adipocytes/pathology ; Animals ; Bone Density/drug effects ; Bone Marrow/drug effects ; Bone Marrow/pathology ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/isolation & purification ; Drugs, Chinese Herbal/pharmacology ; Eucommiaceae/chemistry ; Female ; Medicine, Chinese Traditional ; Organometallic Compounds/administration & dosage ; Organometallic Compounds/pharmacology ; Osteogenesis/drug effects ; Osteoporosis/chemically induced ; Osteoporosis/drug therapy ; Plant Extracts/chemistry ; Plant Extracts/isolation & purification ; Plant Extracts/pharmacology ; Rats ; Rats, Sprague-Dawley
    Chemische Substanzen Drugs, Chinese Herbal ; Organometallic Compounds ; Plant Extracts ; lead acetate (RX077P88RY)
    Sprache Englisch
    Erscheinungsdatum 2018-05-09
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 445336-0
    ISSN 1559-0720 ; 0163-4984
    ISSN (online) 1559-0720
    ISSN 0163-4984
    DOI 10.1007/s12011-018-1362-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Buch: Yue du zhong wen

    Zhu, Ziyi / Zheng, Rui

    = Reading Chinese This Way

    2010  

    Verfasserangabe Zhu Ziyi; Zheng Rui bian
    Sprache Chinesisch
    Umfang iv, 152 S.
    Ausgabenhinweis 2. Druck
    Verlag Gao deng jiao yu chu ban she
    Erscheinungsort Beijing
    Dokumenttyp Buch
    Begleitmaterial 1 CD
    ISBN 9787040276886 ; 7040276887
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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  6. Buch: Yue du zhong wen

    Zhu, Ziyi / Zheng, Rui

    = Reading Chinese This Way

    2010  

    Verfasserangabe Zhu Ziyi; Zheng Rui bian
    Sprache Chinesisch
    Umfang iii, 139 S.
    Ausgabenhinweis 2. Druck
    Verlag Gao deng jiao yu chu ban she
    Erscheinungsort Beijing
    Dokumenttyp Buch
    Begleitmaterial 1 CD
    ISBN 9787040250985 ; 7040250985
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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  7. Buch: Yue du zhong wen

    Zhu, Ziyi / Zheng, Rui

    = Reading Chinese This Way

    2010  

    Verfasserangabe Zhu Ziyi; Zheng Rui bian
    Sprache Chinesisch
    Umfang iv, 143 S.
    Ausgabenhinweis 2. Druck
    Verlag Gao deng jiao yu chu ban she
    Erscheinungsort Beijing
    Dokumenttyp Buch
    Begleitmaterial 1 CD
    ISBN 9787040276893 ; 7040276895
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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  8. Buch: Yue du zhong wen

    Zhu, Ziyi / Zheng, Rui

    = Reading Chinese This Way

    2010  

    Verfasserangabe Zhu Ziyi; Zheng Rui bian
    Sprache Chinesisch
    Umfang iii, 113 S.
    Ausgabenhinweis 2. Druck
    Verlag Gao deng jiao yu chu ban she
    Erscheinungsort Beijing
    Dokumenttyp Buch
    Begleitmaterial 1 CD
    ISBN 9787040247732 ; 7040247739
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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  9. Buch: Yue du zhong wen

    Zhu, Ziyi / Zheng, Rui

    = Reading Chinese This Way

    2010  

    Verfasserangabe Zhu Ziyi; Zheng Rui bian
    Sprache Chinesisch
    Umfang iv, 170 S.
    Ausgabenhinweis 2. Druck
    Verlag Gao deng jiao yu chu ban she
    Erscheinungsort Beijing
    Dokumenttyp Buch
    Begleitmaterial 1 CD
    ISBN 9787040266139 ; 704026613X
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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  10. Buch: Yue du zhong wen

    Zhu, Ziyi / Zheng, Rui

    Reading Chinese This Way

    2010  

    Verfasserangabe Zhu Ziyi; Zheng Rui bian
    Sprache Chinesisch
    Ausgabenhinweis 2. Druck
    Verlag Gao deng jiao yu chu ban she
    Erscheinungsort Beijing
    Dokumenttyp Buch
    Datenquelle Ehemaliges Sondersammelgebiet Küsten- und Hochseefischerei

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