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Artikel ; Online: Iron control of erythroid microtubule cytoskeleton as a potential target in treatment of iron-restricted anemia

Adam N. Goldfarb / Katie C. Freeman / Ranjit K. Sahu / Kamaleldin E. Elagib / Maja Holy / Abhinav Arneja / Renata Polanowska-Grabowska / Alejandro A. Gru / Zollie White / Shadi Khalil / Michael J. Kerins / Aikseng Ooi / Norbert Leitinger / Chance John Luckey / Lorrie L. Delehanty

Nature Communications, Vol 12, Iss 1, Pp 1-

2021  Band 14

Abstract: Debilitating anemias in chronic diseases can result from deficient iron delivery to red cell precursors. Here, the authors show how this deficiency damages the cytoskeletal framework of progenitor cells and identify a targeted strategy for cytoskeletal ... ...

Abstract Debilitating anemias in chronic diseases can result from deficient iron delivery to red cell precursors. Here, the authors show how this deficiency damages the cytoskeletal framework of progenitor cells and identify a targeted strategy for cytoskeletal repair, leading to anemia correction.
Schlagwörter Science ; Q
Sprache Englisch
Erscheinungsdatum 2021-03-01T00:00:00Z
Verlag Nature Portfolio
Dokumenttyp Artikel ; Online
Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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