Artikel: A synergistic blend of
2023 Band 67
Abstract: Background: A proprietary combination of : Objective: This study assessed the underlying mechanisms of the ergogenic potential of LI80020F4 in : Methods: The individual extracts and their combination (LI80020F4) were assessed for nitrite ... ...
Abstract | Background: A proprietary combination of Objective: This study assessed the underlying mechanisms of the ergogenic potential of LI80020F4 in Methods: The individual extracts and their combination (LI80020F4) were assessed for nitrite production in EAhy926 human endothelial cells. Subsequent experiments evaluated the effect of LI80020F4 in myotube formation in C2C12 mouse myoblasts, expression of mammalian target of rapamycin (mTOR) signaling proteins, myogenic factors, and mitochondrial functions in L6 rat myoblasts.Moreover, adult male ICR mice were randomly assigned ( Results: LI80020F4 increased nitrite production in EAhy926 cells in a dose-dependent manner. LI80020F4 induced C2C12 myotube formation, increased mitochondrial biogenesis, upregulated the expressions of activated mTOR and other mitochondria and myogenic proteins, and mitigated H Conclusion: LI80020F4 increases nitric oxide production in the endothelial cells, mitochondrial biogenesis and function, upregulates skeletal muscle growth-related protein expressions and reduces oxidative stress; together, it explains the basis of the ergogenic potential of LI80020F4. |
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Sprache | Englisch |
Erscheinungsdatum | 2023-10-30 |
Erscheinungsland | Sweden |
Dokumenttyp | Journal Article |
ZDB-ID | 2418338-6 |
ISSN | 1654-661X |
ISSN | 1654-661X |
DOI | 10.29219/fnr.v67.9750 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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