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  1. Artikel: Cardioprotective properties of Artemisia herba alba nanoparticles against heart attack in rats: A study of the antioxidant and hypolipidemic activities.

    Alshehri, Mohammed Ali

    Saudi journal of biological sciences

    2021  Band 29, Heft 4, Seite(n) 2336–2347

    Abstract: Recently, pharmaceutical scientists' interest has increased to find novel pharmaceutical natural substances with potent antioxidant capacity and very low side effects to be used safely in preventive medicine. One of the most common types of diseases with ...

    Abstract Recently, pharmaceutical scientists' interest has increased to find novel pharmaceutical natural substances with potent antioxidant capacity and very low side effects to be used safely in preventive medicine. One of the most common types of diseases with a large spread globally is cardiovascular diseases, which cause a high rate of deaths annually. The present study evaluated the use of
    Sprache Englisch
    Erscheinungsdatum 2021-12-13
    Erscheinungsland Saudi Arabia
    Dokumenttyp Journal Article
    ZDB-ID 2515206-3
    ISSN 2213-7106 ; 1319-562X
    ISSN (online) 2213-7106
    ISSN 1319-562X
    DOI 10.1016/j.sjbs.2021.12.009
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  2. Artikel: Evaluation of

    Asiri, Saeed Ahmed / Shabnam, Madeeha / Zafar, Rehman / Alshehri, Osama M / Alshehri, Mohammed Ali / Sadiq, Abdul / Mahnashi, Mater H / Jan, Muhammad Saeed

    Frontiers in chemistry

    2024  Band 12, Seite(n) 1351827

    Abstract: Habenaria ... ...

    Abstract Habenaria aitchisonii
    Sprache Englisch
    Erscheinungsdatum 2024-03-19
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2711776-5
    ISSN 2296-2646
    ISSN 2296-2646
    DOI 10.3389/fchem.2024.1351827
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  3. Artikel ; Online: Insights into the Biological Activities and Substituent Effects of Pyrrole Derivatives: The Chemistry-Biology Connection.

    Manya, B S / Kumar M R, Pradeep / Rajagopal, Kalirajan / Hassan, Md Abul / Rab, Safia Obaidur / Alshehri, Mohammed Ali / Emran, Talha Bin

    Chemistry & biodiversity

    2024  , Seite(n) e202400534

    Abstract: Pyrrole, with its versatile heterocyclic ring structure, serves as a valuable template for generating a diverse range of lead compounds with various pharmacophores. Researchers and scientists globally are intrigued by pyrrole and its analogues for their ... ...

    Abstract Pyrrole, with its versatile heterocyclic ring structure, serves as a valuable template for generating a diverse range of lead compounds with various pharmacophores. Researchers and scientists globally are intrigued by pyrrole and its analogues for their broad pharmacological potential, prompting thorough investigations aimed at advancing human welfare. This comprehensive review delves into the diverse activities exhibited by pyrrole compounds, encompassing their synthesis, reactions, and pharmacological properties alongside their derivatives. In addition to detailing the characteristics of pyrrole and its derivatives within the context of green chemistry, the review also examines microwave-assisted reactions. It provides insights into their chemical structures, natural occurrences, and potential applications across various domains. Furthermore, the article investigates structural alterations of pyrrole compounds and their implications on their functionality, highlighting their versatility as foundational elements for both functional materials and bioactive compounds. Ultimately, the review underscores the imperative for continued research and development in the realm of pyrrole compounds to unearth novel activities and advantages.
    Sprache Englisch
    Erscheinungsdatum 2024-05-21
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2139001-0
    ISSN 1612-1880 ; 1612-1872
    ISSN (online) 1612-1880
    ISSN 1612-1872
    DOI 10.1002/cbdv.202400534
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  4. Artikel ; Online: Larvicidal potential of Cipadessa baccifera leaf extract-synthesized zinc nanoparticles against three major mosquito vectors

    Ramkumar Govindaraju / Shivakumar Muthugoundar Subramanian / Alshehri Mohammed Ali / Panneerselvam Chellasamy / Sayed Samy

    Green Processing and Synthesis, Vol 11, Iss 1, Pp 757-

    2022  Band 765

    Abstract: Mosquitoes are important vectors, which transmit many communicable diseases throughout the world. Synthetic insecticides, such as organophosphate and pyrethroids, are commonly used for their control in the vector control program. Insecticidal compounds ... ...

    Abstract Mosquitoes are important vectors, which transmit many communicable diseases throughout the world. Synthetic insecticides, such as organophosphate and pyrethroids, are commonly used for their control in the vector control program. Insecticidal compounds from natural sources, notably from plants and synthesized nanoparticles (NPs) are promising tools for managing such vectors. Hence, the study aimed to analyze the insecticidal potentiality of leaf extract of Cipadessa baccifera and synthesized ZnNPs against three major mosquito vectors. The results recorded from UV-Vis spectroscopy show the peak absorption spectrum at 420 nm. In FTIR, the maximum peak value is 562.85 cm−1 assigned to the N–H group (amide group). The EDAX analysis shows a peak around 63.29, which confirms the binding intensity of selenium. In the scanning electron microscopy analysis, the synthesized ZnNPs sizes were ranging from 49.21 to 65.43 nm. The synthesized ZnNPs produced high mortality against Culex quinquefasciatus LC50 = 0.049653 mg·mL−1; LC90 = 0.9842 mg·mL−1), Anopheles stephensi (LC50 = 0.053421 mg·mL−1 and LC90 = 0.027761 mg·mL−1), and Aedes aegypti LC50 = 0.55214 mg·mL−1 and LC90 = 0.7456 mg·mL−1). These results suggest that the C. baccifera leaf extract-mediated biosynthesis of ZnNPs has the potential to be used as an ideal eco-friendly approach toward the control of mosquito vectors at early stages.
    Schlagwörter botanical extracts ; bionanopesticides ; cipadessa baccifera ; vector control ; Chemistry ; QD1-999
    Thema/Rubrik (Code) 540
    Sprache Englisch
    Erscheinungsdatum 2022-08-01T00:00:00Z
    Verlag De Gruyter
    Dokumenttyp Artikel ; Online
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  5. Artikel ; Online: Efficacy of chitosan silver nanoparticles from shrimp-shell wastes against major mosquito vectors of public health importance

    Alshehri Mohammed Ali / Aziz Al Thabiani / Trivedi Subrata / Panneerselvam Chellasamy

    Green Processing and Synthesis, Vol 9, Iss 1, Pp 675-

    2020  Band 684

    Abstract: Mosquito-borne diseases are causing serious damage to public health worldwide, and control of these deadly mosquito vectors is a major thrust area for epidemiologists and public health workers. Therefore, the present research reports an eco-friendly ... ...

    Abstract Mosquito-borne diseases are causing serious damage to public health worldwide, and control of these deadly mosquito vectors is a major thrust area for epidemiologists and public health workers. Therefore, the present research reports an eco-friendly solution with multipotency of silver nanoparticle fabricated from shrimp shell biowaste in controlling mosquitoes and bacterial pathogens. The biofabricated chitosan silver nanoparticles (Cs-AgNPs) were confirmed by UV-visible spectroscopy, transmission electron microscopy (TEM), Fourier transform infrared spectroscopy, energy dispersive X-ray spectroscopy, X-ray powder diffraction and zeta potential analysis. The TEM studies showed that the obtained Cs-AgNPs were mostly spherical in shape. Low doses of chitosan and Cs-AgNPs showed high mosquitocidal properties against both larvae and adult of Anopheles stephensi, Aedes aegypti, and Culex quinquefasciatus. The LC50 (lethal concentration 50%) of Cs-AgNPs was 10.240 ppm (fourth instar larvae) and 9.671 ppm (adult) for An. stephensi; 11.349 ppm (fourth instar) and 12.015 ppm (adult) for Ae. aegypti and 12.426 ppm (fourth instar) and 12.965 ppm (adult) for Cx. quinquefasciatus. The concerning part of antibacterial studies showed that Cs-AgNP had significant inhibition on tested bacterial pathogens. Overall, this study shows that chitosan extracted from the shrimp shell wastes can be used as a potential source for controlling major mosquito vectors.
    Schlagwörter shrimp shells ; larvicidal ; adulticidal ; green synthesis ; antibacterial activity ; Chemistry ; QD1-999
    Sprache Englisch
    Erscheinungsdatum 2020-11-01T00:00:00Z
    Verlag De Gruyter
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel: An unusual case of gastric angiolipoma presenting with upper gastrointestinal bleeding.

    Alghamdi, Saeed Abdulrahman / Alshammery, Sahar Matter / Alamari, Mahammad Saeed / Alshehri, Mohammed Ali / Alshahrani, Amer Saeed

    Oxford medical case reports

    2022  Band 2022, Heft 11, Seite(n) omac119

    Abstract: Gastric angiolipomas (GA) are rare benign tumors that can present with gastrointestinal bleeding and anemia. We describe a 73-year-old woman who presented with a 3-day history of fatiguability, epigastric pain and melena. A computed tomography scan ... ...

    Abstract Gastric angiolipomas (GA) are rare benign tumors that can present with gastrointestinal bleeding and anemia. We describe a 73-year-old woman who presented with a 3-day history of fatiguability, epigastric pain and melena. A computed tomography scan revealed a hypodense lesion, measuring 6 × 6 × 5 cm, along the upper part of the stomach. An upper endoscopy revealed a large polypoid lesion, measuring 8 × 6 cm, between the cardia and body of the stomach. Multiple biopsy specimens were taken, and a histopathological examination showed an acute erosive helicobacter-associated reactive gastritis but no definitive atypia. A linear endoscopic ultrasound revealed a large, homogenous, hyperechoic lesion, consistent with a lipoma, in the body of the stomach. A fine needle aspiration was negative for malignancy. A laparoscopy was offered, and a wedge resection was performed. A histopathological examination revealed a well-circumscribed, encapsulated lipomatous tumor in the gastric submucosa with focal mucosal ulceration. The patient had an uneventful postoperative recovery and her hemoglobin level subsequently returned to normal. Overall, clinicians may be unfamiliar with GA because patients may present with signs and symptoms that can be confused with other gastrointestinal conditions. Physicians should be aware of the characteristic histopathological features to distinguish GA from other diseases of the gastrointestinal tract that may share similar clinical or radiologic features.
    Sprache Englisch
    Erscheinungsdatum 2022-11-24
    Erscheinungsland England
    Dokumenttyp Case Reports
    ZDB-ID 2766251-2
    ISSN 2053-8855
    ISSN 2053-8855
    DOI 10.1093/omcr/omac119
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  7. Artikel ; Online: Green synthesis of ZnO-NPs using endophytic fungal extract of

    Nehru, Lavanya / Kandasamy, Gayathri Devi / Sekar, Vanaraj / Alshehri, Mohammed Ali / Panneerselvam, Chellasamy / Alasmari, Abdulrahman / Kathirvel, Preethi

    Artificial cells, nanomedicine, and biotechnology

    2023  Band 51, Heft 1, Seite(n) 318–333

    Abstract: The biogenic manufacture of nanoparticles utilising endophytic fungus is an eco-friendly, cost-effective, and secure alternative to constructing chemical methods. The prime focus of the study was to fabricate ZnONPs using the biomass filtrate of ... ...

    Abstract The biogenic manufacture of nanoparticles utilising endophytic fungus is an eco-friendly, cost-effective, and secure alternative to constructing chemical methods. The prime focus of the study was to fabricate ZnONPs using the biomass filtrate of endophytic
    Mesh-Begriff(e) Zinc Oxide/pharmacology ; Antioxidants ; Ascomycota ; Asteraceae ; Plant Extracts/pharmacology
    Chemische Substanzen Zinc Oxide (SOI2LOH54Z) ; Antioxidants ; Plant Extracts
    Sprache Englisch
    Erscheinungsdatum 2023-07-01
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2723095-8
    ISSN 2169-141X ; 2169-1401
    ISSN (online) 2169-141X
    ISSN 2169-1401
    DOI 10.1080/21691401.2023.2232654
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  8. Artikel ; Online: TiO

    Subramanian, Rajaduraipandian / Ponnanikajamideen, Mohemedibrahim / Samuel Rajendran, Rapael / Alshehri, Mohammed Ali / Alasmari, Abdulrahman / Panneerselvam, Chellasamy / Periyasamy, Selvendiran

    Drug and chemical toxicology

    2023  Band 47, Heft 1, Seite(n) 90–100

    Abstract: The present study was designed to green synthesize titanium dioxide nanoparticles (G- ... ...

    Abstract The present study was designed to green synthesize titanium dioxide nanoparticles (G-TiO
    Mesh-Begriff(e) Animals ; Zebrafish ; Metal Nanoparticles/toxicity ; Nanoparticles ; Anti-Infective Agents ; Anti-Bacterial Agents/toxicity ; Titanium/toxicity ; Hypoglycemic Agents ; Anti-Inflammatory Agents
    Chemische Substanzen Anti-Infective Agents ; Anti-Bacterial Agents ; Titanium (D1JT611TNE) ; Hypoglycemic Agents ; Anti-Inflammatory Agents
    Sprache Englisch
    Erscheinungsdatum 2023-06-14
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 548368-2
    ISSN 1525-6014 ; 0148-0545
    ISSN (online) 1525-6014
    ISSN 0148-0545
    DOI 10.1080/01480545.2023.2217697
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  9. Artikel ; Online: Ameliorated antimicrobial, antioxidant, and anticancer properties by Plectranthus vettiveroides root extract-mediated green synthesis of chitosan nanoparticles

    Venkatesan Kamalesh Balakumar / Alamelu Saravanan / Priya Sivamathi Rathna / Jayaseelan Nivedha / Kamaraj Sathish-Kumar / Srinivasan Manoj Kumar / Alshehri Mohammed Ali / Panneerselvam Chellasamy / Saif Ahmed / Periyasamy Selvendiran

    Green Processing and Synthesis, Vol 12, Iss 1, Pp 61-

    2023  Band 9

    Schlagwörter antibacterial ; anticancer ; antioxidant ; chitosan nanoparticles ; plectranthus vettiveroides ; Chemistry ; QD1-999
    Sprache Englisch
    Erscheinungsdatum 2023-10-01T00:00:00Z
    Verlag De Gruyter
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  10. Artikel ; Online: Anticancer, anti-proliferative activity of

    Albinhassan, Tahani H / Saleh, Kamel A / Barhoumi, Zouhaier / Alshehri, Mohammed Ali / Al-Ghazzawi, Adel M

    Journal of cancer research and therapeutics

    2021  Band 17, Heft 4, Seite(n) 879–886

    Abstract: Purpose: Medical halophytes plants are potent sources of bioactive secondary metabolite components used against different diseases. Avicenniamarina one of the typical halophytes plant species used in folk medicine to treat smallpox, rheumatism, and ... ...

    Abstract Purpose: Medical halophytes plants are potent sources of bioactive secondary metabolite components used against different diseases. Avicenniamarina one of the typical halophytes plant species used in folk medicine to treat smallpox, rheumatism, and ulcer. Despite the richness of A.marina with polyphenolic, flavonoids, terpenoid, and terpene, contents remain poorly investigated against cancer types. Consequently, to explore the function-composition relationship of A.marina hexane leaves crude extract, the current study designed to investigate the cytotoxicity, apoptotic and antiproliferative impacts on the colon (HCT-116), liver (HepG2), and breast (MCF-7) cancer cell lines.
    Materials and methods: Therefore, the cytotoxicity impact screening carried out by Sulforhodamine-B assay. While, the initiation of the apoptosis evaluated by chromatin condensing, early apoptosis, late apoptosis and the formation and appearance of apoptotic bodies. On the other hand, the flow cytometry used to identify the phase of inhibition where the determined IC
    Results: Revealed that hexane extract showed a weak induction of apoptosis despite the formation of apoptotic bodies and the high cell inhibitory effect on all tested cell lines with IC
    Conclusion: In the light of these results, the current study suggests that A.marina leaves hexane extract may be considered as a candidate for further anticancer drug development investigations.
    Mesh-Begriff(e) Apoptosis ; Avicennia/chemistry ; Cell Cycle ; Cell Proliferation ; HCT116 Cells ; Hep G2 Cells ; Humans ; MCF-7 Cells ; Neoplasms/drug therapy ; Neoplasms/pathology ; Plant Extracts/pharmacology ; Plant Leaves/chemistry
    Chemische Substanzen Plant Extracts
    Sprache Englisch
    Erscheinungsdatum 2021-09-08
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2187633-2
    ISSN 1998-4138 ; 0973-1482
    ISSN (online) 1998-4138
    ISSN 0973-1482
    DOI 10.4103/jcrt.JCRT_659_19
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