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  1. Artikel: Healthcare-Associated Bloodstream Infections Due to Multidrug-Resistant

    Dobrović, Karolina / Škrobo, Tea / Selec, Katarina / Jelić, Marko / Čivljak, Rok / Peršec, Jasminka / Sakan, Sanja / Bušić, Nikolina / Mihelčić, Antonija / Hleb, Sonja / Andrašević, Arjana Tambić

    Microorganisms

    2023  Band 11, Heft 3

    Abstract: Healthcare-associated infections are an emerging cause of morbidity and mortality in COVID-19 intensive care units (ICUs) worldwide, especially those caused by multidrug-resistant (MDR) pathogens. The objectives of this study were to assess the incidence ...

    Abstract Healthcare-associated infections are an emerging cause of morbidity and mortality in COVID-19 intensive care units (ICUs) worldwide, especially those caused by multidrug-resistant (MDR) pathogens. The objectives of this study were to assess the incidence of bloodstream infections (BSIs) among critically ill COVID-19 patients and to analyze the characteristics of healthcare-associated BSIs due to MDR
    Sprache Englisch
    Erscheinungsdatum 2023-03-17
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11030774
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: In vitro activity of tigecycline and comparators against Gram-negative pathogens isolated from blood in Europe (2004-2009).

    Andrasevic, Arjana Tambic / Dowzicky, Michael J

    International journal of antimicrobial agents

    2012  Band 39, Heft 2, Seite(n) 115–123

    Abstract: Here we report on the antimicrobial resistance amongst Gram-negative isolates (excluding Acinetobacter spp.) collected from blood culture sources at European study sites as part of the global Tigecycline Evaluation and Surveillance Trial (T.E.S.T.) from ... ...

    Abstract Here we report on the antimicrobial resistance amongst Gram-negative isolates (excluding Acinetobacter spp.) collected from blood culture sources at European study sites as part of the global Tigecycline Evaluation and Surveillance Trial (T.E.S.T.) from the study start in 2004 until August 2009. All isolates were collected and tested for minimum inhibitory concentrations using Clinical and Laboratory Standards Institute methodology. Over the collection period, extended-spectrum β-lactamase (ESBL) production was recorded in 21.1% of Klebsiella pneumoniae, 2.6% of Klebsiella oxytoca and 11.3% of Escherichia coli, primarily in Croatia, Greece, Hungary, Italy, Poland, Romania and the Slovak Republic. ESBL rates stabilised amongst K. pneumoniae over 2006-2009, but doubled amongst E. coli in 2008-2009. The patterns of antimicrobial resistance changed accordingly for both organisms. Generally, Greece had the highest antimicrobial resistance for K. pneumoniae, Italy for E. coli, Serratia marcescens and Enterobacter spp., and Croatia for Pseudomonas aeruginosa. High resistance rates amongst K. pneumoniae were also seen in Croatia and Italy. Imipenem resistance amongst K. pneumoniae was reported exclusively in Greece (13.8%); amongst other Enterobacteriaceae, imipenem resistance was absent or low. Similarly, meropenem resistance was low amongst the Enterobacteriaceae except K. pneumoniae from Greece (42.6%). Across Europe, the most active antimicrobial agents against the Enterobacteriaceae were tigecycline, amikacin and the carbapenems, each with <10% resistance each year. Against the other antimicrobials, significant increases in non-susceptibility were reported for K. pneumoniae and E. coli, both important causative pathogens of bacteraemia.
    Mesh-Begriff(e) Anti-Bacterial Agents/pharmacology ; Bacteremia/microbiology ; Blood/microbiology ; Europe ; Gram-Negative Bacteria/drug effects ; Gram-Negative Bacteria/isolation & purification ; Gram-Negative Bacterial Infections/microbiology ; Humans ; Microbial Sensitivity Tests ; Minocycline/analogs & derivatives ; Minocycline/pharmacology ; beta-Lactamases/secretion
    Chemische Substanzen Anti-Bacterial Agents ; tigecycline (70JE2N95KR) ; beta-Lactamases (EC 3.5.2.6) ; Minocycline (FYY3R43WGO)
    Sprache Englisch
    Erscheinungsdatum 2012-02
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1093977-5
    ISSN 1872-7913 ; 0924-8579
    ISSN (online) 1872-7913
    ISSN 0924-8579
    DOI 10.1016/j.ijantimicag.2011.10.010
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Successful containment of the first KPC-producing Klebsiella pneumoniae outbreak in Croatia.

    Brkic, Dijana Varda / Pristas, Irina / Cipris, Ivan / Jelic, Marko / Butic, Iva / Andrasevic, Arjana Tambic

    Future microbiology

    2017  Band 12, Seite(n) 967–974

    Abstract: Aim: We report the first outbreak caused by Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae sequence type 258 (ST 258) clone that occurred in Croatia from May to December 2012.: Materials & methods: 23 carbapenem-resistant K. ... ...

    Abstract Aim: We report the first outbreak caused by Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae sequence type 258 (ST 258) clone that occurred in Croatia from May to December 2012.
    Materials & methods: 23 carbapenem-resistant K. pneumoniae isolates were recovered from clinical and screening specimens of 12 patients hospitalized in a regional hospital. The first isolates from the 12 patients were typed using pulsed-field gel electrophoresis and multilocus sequence typing.
    Results: PCR detection showed that all isolates harbored the bla
    Conclusion: The rapid detection of KPC-producing K. pneumoniae and vigorous implementation of infection control measures were necessary to successfully control the outbreak.
    Mesh-Begriff(e) Bacterial Proteins/genetics ; Bacterial Proteins/isolation & purification ; Bacterial Typing Techniques ; Carbapenems/pharmacology ; Croatia/epidemiology ; DNA, Bacterial ; Disease Outbreaks ; Drug Resistance, Bacterial ; Electrophoresis, Gel, Pulsed-Field ; Genes, Bacterial/genetics ; Hospitals ; Humans ; Klebsiella Infections/diagnosis ; Klebsiella Infections/epidemiology ; Klebsiella pneumoniae/enzymology ; Klebsiella pneumoniae/genetics ; Klebsiella pneumoniae/isolation & purification ; Klebsiella pneumoniae/pathogenicity ; Microbial Sensitivity Tests ; Molecular Epidemiology ; Multilocus Sequence Typing ; Polymerase Chain Reaction ; beta-Lactam Resistance/genetics ; beta-Lactamases/genetics ; beta-Lactamases/isolation & purification
    Chemische Substanzen Bacterial Proteins ; Carbapenems ; DNA, Bacterial ; beta-lactamase SHV-11 (EC 3.5.2.-) ; beta-Lactamases (EC 3.5.2.6) ; beta-lactamase TEM-116, Pseudomonas aeruginosa (EC 3.5.2.6) ; carbapenemase (EC 3.5.2.6) ; carbapenemase-2, Klebsiella pneumoniae (EC 3.5.2.6)
    Sprache Englisch
    Erscheinungsdatum 2017
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 1746-0921
    ISSN (online) 1746-0921
    DOI 10.2217/fmb-2016-0143
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: In vitro activity of tigecycline and comparators against Gram-negative pathogens isolated from blood in Europe (2004–2009)

    Andrasevic, Arjana Tambic / Dowzicky, Michael J

    International journal of antimicrobial agents. 2012 Feb., v. 39, no. 2

    2012  

    Abstract: Here we report on the antimicrobial resistance amongst Gram-negative isolates (excluding Acinetobacter spp.) collected from blood culture sources at European study sites as part of the global Tigecycline Evaluation and Surveillance Trial (T.E.S.T.) from ... ...

    Abstract Here we report on the antimicrobial resistance amongst Gram-negative isolates (excluding Acinetobacter spp.) collected from blood culture sources at European study sites as part of the global Tigecycline Evaluation and Surveillance Trial (T.E.S.T.) from the study start in 2004 until August 2009. All isolates were collected and tested for minimum inhibitory concentrations using Clinical and Laboratory Standards Institute methodology. Over the collection period, extended-spectrum β-lactamase (ESBL) production was recorded in 21.1% of Klebsiella pneumoniae, 2.6% of Klebsiella oxytoca and 11.3% of Escherichia coli, primarily in Croatia, Greece, Hungary, Italy, Poland, Romania and the Slovak Republic. ESBL rates stabilised amongst K. pneumoniae over 2006–2009, but doubled amongst E. coli in 2008–2009. The patterns of antimicrobial resistance changed accordingly for both organisms. Generally, Greece had the highest antimicrobial resistance for K. pneumoniae, Italy for E. coli, Serratia marcescens and Enterobacter spp., and Croatia for Pseudomonas aeruginosa. High resistance rates amongst K. pneumoniae were also seen in Croatia and Italy. Imipenem resistance amongst K. pneumoniae was reported exclusively in Greece (13.8%); amongst other Enterobacteriaceae, imipenem resistance was absent or low. Similarly, meropenem resistance was low amongst the Enterobacteriaceae except K. pneumoniae from Greece (42.6%). Across Europe, the most active antimicrobial agents against the Enterobacteriaceae were tigecycline, amikacin and the carbapenems, each with <10% resistance each year. Against the other antimicrobials, significant increases in non-susceptibility were reported for K. pneumoniae and E. coli, both important causative pathogens of bacteraemia.
    Schlagwörter Acinetobacter ; Enterobacter ; Escherichia coli ; Klebsiella oxytoca ; Klebsiella pneumoniae ; Pseudomonas aeruginosa ; Serratia marcescens ; amikacin ; antibiotic resistance ; bacteremia ; beta-lactamase ; blood ; imipenem ; minimum inhibitory concentration ; monitoring ; pathogens ; tigecycline ; Croatia ; Greece ; Hungary ; Italy ; Poland ; Romania ; Slovakia
    Sprache Englisch
    Erscheinungsverlauf 2012-02
    Umfang p. 115-123.
    Erscheinungsort Elsevier B.V.
    Dokumenttyp Artikel
    ZDB-ID 1093977-5
    ISSN 0924-8579
    ISSN 0924-8579
    DOI 10.1016/j.ijantimicag.2011.10.010
    Datenquelle NAL Katalog (AGRICOLA)

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  5. Artikel: MRSA surveillance programmes worldwide: moving towards a harmonised international approach

    Baede, Valérie O. / David, Michael Z. / Andrasevic, Arjana Tambic / Blanc, Dominique S. / Borg, Michael / Brennan, Grainne / Catry, Boudewijn / Chabaud, Aurélie / Empel, Joanna / Enger, Hege / Hallin, Marie / Ivanova, Marina / Kronenberg, Andreas / Kuntaman, Kuntaman / Larsen, Anders Rhod / Latour, Katrien / Lindsay, Jodi A. / Pichon, Bruno / Santosaningsih, Dewi /
    Schouls, Leo M. / Vandenesch, François / Werner, Guido / Żabicka, Dorota / Žemličková, Helena / Seifert, Harald / Vos, Margreet C.

    International journal of antimicrobial agents. 2022 Mar., v. 59, no. 3

    2022  

    Abstract: Multinational surveillance programmes for methicillin-resistant Staphylococcus aureus (MRSA) are dependent on national structures for data collection. This study aimed to capture the diversity of national MRSA surveillance programmes and to propose a ... ...

    Körperschaft MRSA Surveillance Worldwide Study Group (ISAC), the ESCMID Study Group for Nosocomial Infections (ESGNI), the ESCMID Study Group for Staphylococci and Staphylococcal Diseases (ESGS)
    Abstract Multinational surveillance programmes for methicillin-resistant Staphylococcus aureus (MRSA) are dependent on national structures for data collection. This study aimed to capture the diversity of national MRSA surveillance programmes and to propose a framework for harmonisation of MRSA surveillance. The International Society of Antimicrobial Chemotherapy (ISAC) MRSA Working Group conducted a structured survey on MRSA surveillance programmes and organised a webinar to discuss the programmes’ strengths and challenges as well as guidelines for harmonisation. Completed surveys represented 24 MRSA surveillance programmes in 16 countries. Several countries reported separate epidemiological and microbiological surveillance. Informing clinicians and national policy-makers were the most common purposes of surveillance. Surveillance of bloodstream infections (BSIs) was present in all programmes. Other invasive infections were often included. Three countries reported active surveillance of MRSA carriage. Methodology and reporting of antimicrobial susceptibility, virulence factors, molecular genotyping and epidemiological metadata varied greatly. Current MRSA surveillance programmes rely upon heterogeneous data collection systems, which hampers international epidemiological monitoring and research. To harmonise MRSA surveillance, we suggest improving the integration of microbiological and epidemiological data, implementation of central biobanks for MRSA isolate collection, and inclusion of a representative sample of skin and soft-tissue infection cases in addition to all BSI cases.
    Schlagwörter antibiotic resistance ; blood flow ; data collection ; drug therapy ; genotyping ; metadata ; methicillin-resistant Staphylococcus aureus ; monitoring ; surveys ; virulence
    Sprache Englisch
    Erscheinungsverlauf 2022-03
    Erscheinungsort Elsevier Ltd
    Dokumenttyp Artikel
    ZDB-ID 1093977-5
    ISSN 1872-7913 ; 0924-8579
    ISSN (online) 1872-7913
    ISSN 0924-8579
    DOI 10.1016/j.ijantimicag.2022.106538
    Datenquelle NAL Katalog (AGRICOLA)

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  6. Artikel ; Online: Characterization of macrolide resistance in bacteria isolated from macrolide-polluted and unpolluted river sediments and clinical sources in Croatia.

    Milaković, Milena / Križanović, Stela / Petrić, Ines / Šimatović, Ana / González-Plaza, Juan J / Gužvinec, Marija / Andrašević, Arjana Tambić / Pole, Lucia / Fuka, Mirna Mrkonjić / Udiković-Kolić, Nikolina

    The Science of the total environment

    2020  Band 749, Seite(n) 142357

    Abstract: Environments polluted with excessively high levels of antibiotics released from manufacturing sites can act as a source of transferable antibiotic resistance (AR) genes to human commensal and pathogenic bacteria. The aim of this study was to evaluate AR ... ...

    Abstract Environments polluted with excessively high levels of antibiotics released from manufacturing sites can act as a source of transferable antibiotic resistance (AR) genes to human commensal and pathogenic bacteria. The aim of this study was to evaluate AR of bacteria isolated from the Sava river sediments (Croatia) at the discharge site of effluents from azithromycin production compared to those from the upstream site and isolates collected in Croatian hospitals. A total of 228 environmental strains of azithromycin-resistant bacteria were isolated and identified, with 124 from the discharge site and 104 from the upstream site. In addition, a total of 90 clinical, azithromycin-resistant streptococcal and staphylococcal isolates obtained from the Croatian Reference Center for Antibiotic Resistance Surveillance were analyzed. PCR screening of isolates on 11 relevant macrolide-resistance genes (MRGs) showed that discharge isolates had greater detection frequencies for 4 gene targets (ermB, msrE, mphE and ermF) compared to upstream isolates. Among clinical isolates, the most frequently detected gene was ermB, followed by msrD, mefE and mefC. The discharge site demonstrated a greater abundance of isolates with co-occurrence of two different MRGs (predominantly msrE-mphE) than the upstream site, but a lower abundance than the clinical sources (most commonly msrD-mefE). The simultaneous presence of three or even four MRGs was specific for the discharge and clinical isolates, but not for the upstream isolates. When MRG results were sorted by gene mechanism, the ribosomal methylation (erm) and protection genes (msr) were the most frequently detected among both the discharge and the clinical isolates. Following sequencing, high nucleotide sequence similarity was observed between ermB in the discharge isolates and the clinical streptococcal isolates, suggesting a possible transfer of the ermB gene between bacteria of clinical and environmental origin. Our study highlights the importance of environmental bacterial populations as reservoirs for clinically relevant macrolide-resistance genes.
    Mesh-Begriff(e) Anti-Bacterial Agents/pharmacology ; Bacteria ; Croatia ; Drug Resistance, Bacterial/genetics ; Humans ; Macrolides ; Microbial Sensitivity Tests ; Rivers
    Chemische Substanzen Anti-Bacterial Agents ; Macrolides
    Sprache Englisch
    Erscheinungsdatum 2020-09-14
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2020.142357
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  7. Artikel ; Online: Staphylococcus aureus

    Gagliotti, Carlo / Högberg, Liselotte Diaz / Billström, Hanna / Eckmanns, Tim / Giske, Christian G / Heuer, Ole E / Jarlier, Vincent / Kahlmeter, Gunnar / Lo Fo Wong, Danilo / Monen, Jos / Murchan, Stephen / Simonsen, Gunnar Skov / Šubelj, Maja / Andrašević, Arjana Tambić / Żabicka, Dorota / Žemličková, Helena / Monnet, Dominique L

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

    2021  Band 26, Heft 46

    Abstract: BackgroundInvasive infections caused ... ...

    Abstract BackgroundInvasive infections caused by
    Mesh-Begriff(e) European Union ; Humans ; Methicillin/pharmacology ; Methicillin-Resistant Staphylococcus aureus ; Sepsis ; Staphylococcal Infections/diagnosis ; Staphylococcal Infections/drug therapy ; Staphylococcal Infections/epidemiology ; Staphylococcus aureus
    Chemische Substanzen Methicillin (Q91FH1328A)
    Sprache Englisch
    Erscheinungsdatum 2021-10-18
    Erscheinungsland Sweden
    Dokumenttyp Journal Article
    ZDB-ID 1338803-4
    ISSN 1560-7917 ; 1025-496X
    ISSN (online) 1560-7917
    ISSN 1025-496X
    DOI 10.2807/1560-7917.ES.2021.26.46.2002094
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: MRSA surveillance programmes worldwide: moving towards a harmonised international approach.

    Baede, Valérie O / David, Michael Z / Andrasevic, Arjana Tambic / Blanc, Dominique S / Borg, Michael / Brennan, Grainne / Catry, Boudewijn / Chabaud, Aurélie / Empel, Joanna / Enger, Hege / Hallin, Marie / Ivanova, Marina / Kronenberg, Andreas / Kuntaman, Kuntaman / Larsen, Anders Rhod / Latour, Katrien / Lindsay, Jodi A / Pichon, Bruno / Santosaningsih, Dewi /
    Schouls, Leo M / Vandenesch, François / Werner, Guido / Żabicka, Dorota / Žemličková, Helena / Seifert, Harald / Vos, Margreet C

    International journal of antimicrobial agents

    2022  Band 59, Heft 3, Seite(n) 106538

    Abstract: Multinational surveillance programmes for methicillin-resistant Staphylococcus aureus (MRSA) are dependent on national structures for data collection. This study aimed to capture the diversity of national MRSA surveillance programmes and to propose a ... ...

    Abstract Multinational surveillance programmes for methicillin-resistant Staphylococcus aureus (MRSA) are dependent on national structures for data collection. This study aimed to capture the diversity of national MRSA surveillance programmes and to propose a framework for harmonisation of MRSA surveillance. The International Society of Antimicrobial Chemotherapy (ISAC) MRSA Working Group conducted a structured survey on MRSA surveillance programmes and organised a webinar to discuss the programmes' strengths and challenges as well as guidelines for harmonisation. Completed surveys represented 24 MRSA surveillance programmes in 16 countries. Several countries reported separate epidemiological and microbiological surveillance. Informing clinicians and national policy-makers were the most common purposes of surveillance. Surveillance of bloodstream infections (BSIs) was present in all programmes. Other invasive infections were often included. Three countries reported active surveillance of MRSA carriage. Methodology and reporting of antimicrobial susceptibility, virulence factors, molecular genotyping and epidemiological metadata varied greatly. Current MRSA surveillance programmes rely upon heterogeneous data collection systems, which hampers international epidemiological monitoring and research. To harmonise MRSA surveillance, we suggest improving the integration of microbiological and epidemiological data, implementation of central biobanks for MRSA isolate collection, and inclusion of a representative sample of skin and soft-tissue infection cases in addition to all BSI cases.
    Mesh-Begriff(e) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Epidemiological Monitoring ; Humans ; Methicillin-Resistant Staphylococcus aureus ; Soft Tissue Infections/drug therapy ; Staphylococcal Infections/drug therapy
    Chemische Substanzen Anti-Bacterial Agents
    Sprache Englisch
    Erscheinungsdatum 2022-01-26
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 1093977-5
    ISSN 1872-7913 ; 0924-8579
    ISSN (online) 1872-7913
    ISSN 0924-8579
    DOI 10.1016/j.ijantimicag.2022.106538
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: RATIONAL THERAPY OF URINARY TRACT INFECTIONS IN CHILDREN IN CROATIA.

    Milošević, Danko / Batinić, Danica / Trkulja, Vladimir / Andrašević, Arjana Tambić / Grčić, Borislav Filipović / Vrljičak, Kristina / Nogalo, Boro / Turudić, Daniel / Spajić, Marija

    Acta clinica Croatica

    2016  Band 55, Heft 3, Seite(n) 428–439

    Mesh-Begriff(e) Anti-Bacterial Agents/therapeutic use ; Anti-Infective Agents, Urinary/therapeutic use ; Antibiotic Prophylaxis/statistics & numerical data ; Child ; Child Welfare/statistics & numerical data ; Child, Preschool ; Critical Pathways ; Croatia ; Drug Resistance, Microbial ; Humans ; Infant ; Practice Guidelines as Topic ; Urinary Tract Infections/drug therapy ; Urinary Tract Infections/epidemiology
    Chemische Substanzen Anti-Bacterial Agents ; Anti-Infective Agents, Urinary
    Sprache Englisch
    Erscheinungsdatum 2016
    Erscheinungsland Croatia
    Dokumenttyp Journal Article
    ZDB-ID 1478635-7
    ISSN 0353-9466
    ISSN 0353-9466
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Antibiotic prescription rate for upper respiratory tract infections and risks for unnecessary prescription in Croatia.

    Botica, Marija Vrca / Botica, Iva / Stamenić, Valerija / Andrasević, Arjana Tambić / Kern, Josipa / Spehar, Stanislava Stojanović

    Collegium antropologicum

    2013  Band 37, Heft 2, Seite(n) 449–454

    Abstract: Overprescribing of antibiotics in primary care has been recognized as public health problem. We investigated visits prescription rate of antibiotics to patients with upper respiratory tract infections (URTI) and unnecessary prescription for ... ...

    Abstract Overprescribing of antibiotics in primary care has been recognized as public health problem. We investigated visits prescription rate of antibiotics to patients with upper respiratory tract infections (URTI) and unnecessary prescription for tonsillopharyngitis, in Croatia. In prospective observational study in November 2007. 25 GPs in Croatia recorded all patients' visits with URTI episode according ICPC-2. Clinical status of patients with tonsillopharyngitis were categorized according to Centor Criteria. 689 visits were analysed, 82% of visits were initial. Antibiotics were prescribed in 44.7% visits with URTI. There were no significant differences in antibiotic prescription rates regarding non-clinical factors. Antibiotics were prescribed to patients with tonsillopharyngitis in 62.2% visits. Unnecessary antibiotics were prescribed (Centor 1,2) in 49.6% visits with tonsillopharyngitis. Logistic regression analysis showed significant differences in unnecessary antibiotic prescription rates only with respect to the workday--Wednesday, CI (1.117-2.671), p = 0.0139. Leading antibiotic was amoxicillin + clavulonic acid, second was amoxicillin, the third were macrolides, the fourth was narrow spectrum penicillin and fifth were cephalosporins. This study shows over prescription for URTI. Unnecessary prescription for tonsillopharyngitis depend on non clinical factor--day of the week. This should be further explored and help to improved prescribe antibiotics.
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; Anti-Bacterial Agents/therapeutic use ; Child ; Croatia/epidemiology ; Drug Prescriptions/statistics & numerical data ; Female ; General Practice/statistics & numerical data ; Humans ; Male ; Middle Aged ; Practice Patterns, Physicians'/statistics & numerical data ; Respiratory Tract Infections/drug therapy ; Respiratory Tract Infections/epidemiology ; Risk Factors ; Unnecessary Procedures/statistics & numerical data ; Young Adult
    Chemische Substanzen Anti-Bacterial Agents
    Sprache Englisch
    Erscheinungsdatum 2013-06
    Erscheinungsland Croatia
    Dokumenttyp Journal Article
    ZDB-ID 233430-6
    ISSN 0350-6134 ; 0353-3735
    ISSN 0350-6134 ; 0353-3735
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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