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Artikel ; Online: Increased glycine contributes to synaptic dysfunction and early mortality in Nprl2 seizure model.

Dentel, Brianne / Angeles-Perez, Lidiette / Ren, Chongyu / Jakkamsetti, Vikram / Holley, Andrew J / Caballero, Daniel / Oh, Emily / Gibson, Jay / Pascual, Juan M / Huber, Kimberly M / Tu, Benjamin P / Tsai, Peter T

iScience

2022  Band 25, Heft 5, Seite(n) 104334

Abstract: Targeted therapies for epilepsies associated with the mTORC1 signaling negative regulator GATOR1 are lacking. NPRL2 is a subunit of the GATOR1 complex and mutations in GATOR1 subunits, ... ...

Abstract Targeted therapies for epilepsies associated with the mTORC1 signaling negative regulator GATOR1 are lacking. NPRL2 is a subunit of the GATOR1 complex and mutations in GATOR1 subunits, including
Sprache Englisch
Erscheinungsdatum 2022-04-29
Erscheinungsland United States
Dokumenttyp Journal Article
ISSN 2589-0042
ISSN (online) 2589-0042
DOI 10.1016/j.isci.2022.104334
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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