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  1. Buch ; Online ; E-Book: Current thoughts on dementia

    Ashraf, Ghulam Md / Sahab Uddin, Md

    from risk factors to therapeutic interventions

    2022  

    Verfasserangabe Ghulam Md Ashraf, Md. Sahab Uddin, editors
    Schlagwörter Dementia/Treatment ; Diseases/Risk factors ; Demència ; Terapèutica
    Thema/Rubrik (Code) 616.83
    Sprache Englisch
    Umfang 1 online resource (621 pages)
    Verlag Springer
    Erscheinungsort Gateway East, Singapore
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-16-7606-2 ; 9789811676055 ; 978-981-16-7606-2 ; 9811676054
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

    Kategorien

  2. Buch ; Online: Advances in Dementia Research

    Ashraf, Ghulam Md

    2019  

    Schlagwörter Physiological & neuro-psychology, biopsychology ; biomarkers, alzheimer's disease, neurodegeneration, metabolic syndrome, memory, enzymes
    Sprache Englisch
    Umfang 1 electronic resource (64 pages)
    Verlag IntechOpen
    Dokumenttyp Buch ; Online
    Anmerkung English
    HBZ-ID HT030645901
    ISBN 9781839621284 ; 1839621281
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

    Zusatzmaterialien

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  3. Buch ; Online ; E-Book: Biological, diagnostic and therapeutic advances in Alzheimer's disease

    Ashraf, Ghulam Md / Alexiou, Athanasios

    non-pharmacological therapies for Alzheimer's disease

    2019  

    Verfasserangabe Ghulam Md Ashraf, Athanasios Alexiou editors
    Schlagwörter Neurosciences ; Neurobiology ; Rehabilitation medicine ; Human genetics
    Thema/Rubrik (Code) 612.8
    Sprache Englisch
    Umfang 1 Online-Ressource (xi, 293 Seiten), Illustrationen
    Verlag Springer
    Erscheinungsort Singapore
    Erscheinungsland Singapur
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020329234
    ISBN 978-981-13-9636-6 ; 9789811396359 ; 981-13-9636-1 ; 9811396353
    DOI 10.1007/978-981-13-9636-6
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

    Kategorien

  4. Buch ; Online ; E-Book: Quality control of cellular protein in neurodegenerative disorders

    Uddin, Sahab / Ashraf, Ghulam Md

    2020  

    Verfasserangabe Md. Sahab Uddin, Ghulam Md. Ashraf
    Schlagwörter Electronic books
    Sprache Englisch
    Umfang 1 Online-Ressource (xx, 515 Seiten), Illustrationen
    Verlag IGI Global
    Erscheinungsort Hershey
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020437997
    ISBN 978-1-79981-318-7 ; 9781799813170 ; 1-79981-318-5 ; 1799813177
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

    Kategorien

  5. Artikel ; Online: Mitochondrial Medicine for Neurological Disorders.

    Sahab Uddin, Md / Alghamdi, Badrah S / Ashraf, Ghulam Md

    Current neuropharmacology

    2023  Band 21, Heft 5, Seite(n) 1024–1025

    Mesh-Begriff(e) Humans ; Mitochondria/genetics ; Nervous System Diseases/therapy ; Mitochondrial Diseases/therapy ; DNA, Mitochondrial
    Chemische Substanzen DNA, Mitochondrial
    Sprache Englisch
    Erscheinungsdatum 2023-05-18
    Erscheinungsland United Arab Emirates
    Dokumenttyp Editorial
    ZDB-ID 2192352-8
    ISSN 1875-6190 ; 1570-159X
    ISSN (online) 1875-6190
    ISSN 1570-159X
    DOI 10.2174/1570159X2105230320095644
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

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  6. Artikel ; Online: New Emerging Trends in Protein and Peptide Based Therapeutic Approaches - Part I.

    Ashraf, Ghulam Md

    Current protein & peptide science

    2018  Band 19, Heft 9, Seite(n) 840

    Mesh-Begriff(e) Humans ; Peptides/therapeutic use ; Proteins/therapeutic use
    Chemische Substanzen Peptides ; Proteins
    Sprache Englisch
    Erscheinungsdatum 2018-08-23
    Erscheinungsland United Arab Emirates
    Dokumenttyp Editorial ; Introductory Journal Article
    ZDB-ID 2045662-1
    ISSN 1875-5550 ; 1389-2037
    ISSN (online) 1875-5550
    ISSN 1389-2037
    DOI 10.2174/138920371909180717093011
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: New Emerging Trends in Protein and Peptide Based Therapeutic Approaches - Part II.

    Ashraf, Ghulam Md

    Current protein & peptide science

    2018  Band 19, Heft 10, Seite(n) 936

    Mesh-Begriff(e) Humans ; Peptides/therapeutic use ; Proteins/therapeutic use
    Chemische Substanzen Peptides ; Proteins
    Sprache Englisch
    Erscheinungsdatum 2018-08-13
    Erscheinungsland United Arab Emirates
    Dokumenttyp Editorial ; Introductory Journal Article
    ZDB-ID 2045662-1
    ISSN 1875-5550 ; 1389-2037
    ISSN (online) 1875-5550
    ISSN 1389-2037
    DOI 10.2174/138920371910180719094236
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Dysregulation of Neuronal Iron in Alzheimer's Disease.

    Uddin, Md Sahab / Ashraf, Ghulam Md

    Current neuropharmacology

    2021  Band 21, Heft 11, Seite(n) 2247–2250

    Mesh-Begriff(e) Humans ; Alzheimer Disease ; Iron ; Neurons
    Chemische Substanzen Iron (E1UOL152H7)
    Sprache Englisch
    Erscheinungsdatum 2021-12-30
    Erscheinungsland United Arab Emirates
    Dokumenttyp Journal Article
    ZDB-ID 2192352-8
    ISSN 1875-6190 ; 1570-159X
    ISSN (online) 1875-6190
    ISSN 1570-159X
    DOI 10.2174/1570159X20666211231163544
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

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  9. Artikel ; Online: Gene Therapy for Neuroprotection and Neurorestoration-Part III.

    Ashraf, Ghulam Md / Uddin, Md Sahab

    Current gene therapy

    2021  Band 21, Heft 1, Seite(n) 2

    Mesh-Begriff(e) Genetic Therapy ; Humans ; Nervous System Diseases/genetics ; Nervous System Diseases/therapy ; Neuroprotection
    Sprache Englisch
    Erscheinungsdatum 2021-02-13
    Erscheinungsland United Arab Emirates
    Dokumenttyp Editorial ; Introductory Journal Article
    ZDB-ID 2146187-9
    ISSN 1875-5631 ; 1566-5232
    ISSN (online) 1875-5631
    ISSN 1566-5232
    DOI 10.2174/156652322101210209103113
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Navigating the Maze of Alzheimer's disease by exploring BACE1: Discovery, current scenario, and future prospects.

    Iram, Faiza / Shahid, Mohammad / Ansari, Jaoud / Ashraf, Ghulam Md / Hassan, Md Imtaiyaz / Islam, Asimul

    Ageing research reviews

    2024  Band 98, Seite(n) 102342

    Abstract: Alzheimer's disease (AD) is a chronic neurological condition that has become a leading cause of cognitive decline in elder individuals. Hardly any effective medication has been developed to halt the progression of AD due to the disease's complexity. ... ...

    Abstract Alzheimer's disease (AD) is a chronic neurological condition that has become a leading cause of cognitive decline in elder individuals. Hardly any effective medication has been developed to halt the progression of AD due to the disease's complexity. Several theories have been put forward to clarify the mechanisms underlying AD etiology. The identification of amyloid plaques as a hallmark of AD has sparked the development of numerous drugs targeting the players involved in the amyloidogenic pathway, such as the β-site of amyloid precursor protein cleavage enzyme 1 (BACE1) blockers. Over the last ten years, preclinical and early experimental research has led several pharmaceutical companies to prioritize producing BACE1 inhibitors. Despite all these efforts, earlier discovered inhibitors were discontinued in consideration of another second-generation small molecules and recent BACE1 antagonists failed in the final stages of clinical trials because of the complications associated either with toxicity or effectiveness. In addition to discussing the difficulties associated with development of BACE1 inhibitors, this review aims to provide an overview of BACE1 and offer perspectives on the causes behind the failure of five recent BACE1 inhibitors, that would be beneficial for choosing effective treatment approaches in the future.
    Sprache Englisch
    Erscheinungsdatum 2024-05-16
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2075672-0
    ISSN 1872-9649 ; 1568-1637
    ISSN (online) 1872-9649
    ISSN 1568-1637
    DOI 10.1016/j.arr.2024.102342
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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