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  1. Artikel: International Conventions & One Health.

    Basu, Atanu / Sandhu, Harpreet

    The Indian journal of medical research

    2021  Band 153, Heft 3, Seite(n) 253–255

    Mesh-Begriff(e) Global Health ; Humans ; International Cooperation ; One Health
    Sprache Englisch
    Erscheinungsdatum 2021-05-19
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.IJMR_644_21
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Transmission electron microscopy imaging of SARS-CoV-2.

    Prasad, Sharda / Potdar, Varsha / Cherian, Sarah / Abraham, Priya / Basu, Atanu

    The Indian journal of medical research

    2020  Band 151, Heft 2 & 3, Seite(n) 241–243

    Mesh-Begriff(e) Betacoronavirus/ultrastructure ; COVID-19 ; Coronavirus Infections ; Humans ; Microscopy, Electron, Transmission ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-05-12
    Erscheinungsland India
    Dokumenttyp Letter
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.IJMR_577_20
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Human herpesvirus 6

    Basu Atanu

    Indian Journal of Human Genetics, Vol 9, Iss 1, Pp 29-

    Catalyst of genomic lesion in dysfunctional hematopoiesis ?

    2003  Band 30

    Schlagwörter Genetics ; QH426-470 ; Biology (General) ; QH301-705.5 ; Science ; Q ; DOAJ:Genetics ; DOAJ:Biology ; DOAJ:Biology and Life Sciences
    Sprache Englisch
    Erscheinungsdatum 2003-01-01T00:00:00Z
    Verlag Medknow Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel: Perspectives for repurposing drugs for the coronavirus disease 2019.

    Cherian, Sarah S / Agrawal, Megha / Basu, Atanu / Abraham, Priya / Gangakhedkar, Raman R / Bhargava, Balram

    The Indian journal of medical research

    2020  Band 151, Heft 2 & 3, Seite(n) 160–171

    Abstract: The newly emerged 2019 novel coronavirus (CoV), named as severe acute respiratory syndrome CoV-2 (SARS-CoV-2), like SARS-CoV (now, SARS-CoV-1) and Middle East respiratory syndrome CoV (MERS-CoV), has been associated with high infection rates with over 36, ...

    Abstract The newly emerged 2019 novel coronavirus (CoV), named as severe acute respiratory syndrome CoV-2 (SARS-CoV-2), like SARS-CoV (now, SARS-CoV-1) and Middle East respiratory syndrome CoV (MERS-CoV), has been associated with high infection rates with over 36,405 deaths. In the absence of approved marketed drugs against coronaviruses, the treatment and management of this novel CoV disease (COVID-19) worldwide is a challenge. Drug repurposing that has emerged as an effective drug discovery approach from earlier approved drugs could reduce the time and cost compared to de novo drug discovery. Direct virus-targeted antiviral agents target specific nucleic acid or proteins of the virus while host-based antivirals target either the host innate immune responses or the cellular machineries that are crucial for viral infection. Both the approaches necessarily interfere with viral pathogenesis. Here we summarize the present status of both virus-based and host-based drug repurposing perspectives for coronaviruses in general and the SARS-CoV-2 in particular.
    Mesh-Begriff(e) Antiviral Agents/therapeutic use ; Betacoronavirus ; Coronavirus Infections/drug therapy ; Drug Discovery ; Drug Repositioning ; Humans ; Molecular Docking Simulation ; Pandemics ; Pneumonia, Viral/drug therapy ; Protease Inhibitors/therapeutic use ; Viral Proteins/antagonists & inhibitors
    Chemische Substanzen Antiviral Agents ; Protease Inhibitors ; Viral Proteins
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-04-21
    Erscheinungsland India
    Dokumenttyp Journal Article ; Review
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.IJMR_585_20
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Transmission electron microscopy imaging of SARS-CoV-2

    Basu, Atanu / Prasad, Sharda / Potdar, Varsha / Cherian, Sarah / Abraham, Priya

    Indian Journal of Medical Research

    2020  

    Schlagwörter General Biochemistry, Genetics and Molecular Biology ; General Medicine ; covid19
    Sprache Englisch
    Verlag Medknow
    Erscheinungsland in
    Dokumenttyp Artikel ; Online
    ZDB-ID 390883-5
    ISSN 0019-5340 ; 0971-5916
    ISSN 0019-5340 ; 0971-5916
    DOI 10.4103/ijmr.ijmr_577_20
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel: Dengue Virus NS1 Exposure Affects von Willebrand Factor Profile and Platelet Adhesion Properties of Cultured Vascular Endothelial Cells.

    Tadkalkar, Nitali / Prasad, Sharda / Gangodkar, Shobha / Ghosh, Kanjaksha / Basu, Atanu

    Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion

    2018  Band 35, Heft 3, Seite(n) 502–506

    Abstract: Hematological abnormalities and altered vascular permeability are frequently encountered in Dengue virus infected patients, but the mechanisms that alter platelet-endothelium interactions remain incompletely understood. The DENV NS1 protein has been ... ...

    Abstract Hematological abnormalities and altered vascular permeability are frequently encountered in Dengue virus infected patients, but the mechanisms that alter platelet-endothelium interactions remain incompletely understood. The DENV NS1 protein has been implicated in adverse disease outcomes. In the present study the role of NS1 protein in affecting the expression of vWF and platelet adhesion properties of endothelial cells was studied in vitro. The results suggest that vWF is down regulated in cultured endothelial cells 6 and 24 h after exposure with increase in vWF levels in culture supernatants at corresponding time points. Ultrastructural studies showed distinct evidence of endothelial cell activation morphology and degranulation of Weibel-Palade bodies in NS1 exposed cells that also showed increased platelet activation physiology. The findings suggest that changes in vWF production and secretion may be induced in endothelial cells exposed to DENV NS1 protein; and play a role in bleeding complications of severe DENV disease.
    Sprache Englisch
    Erscheinungsdatum 2018-12-06
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2422370-0
    ISSN 0974-0449 ; 0971-4502
    ISSN (online) 0974-0449
    ISSN 0971-4502
    DOI 10.1007/s12288-018-1058-2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Electron microscopy imaging of SARS-CoV-2 at different temperatures.

    Prasad, Sharda / Meena, Virendra Kumar / Yadav, Pragya D / Sarkale, Prasad / Baradkar, Shreekant / Cherian, Sarah / Abraham, Priya / Basu, Atanu

    The Indian journal of medical research

    2021  Band 153, Heft 5&6, Seite(n) 692–695

    Mesh-Begriff(e) COVID-19 ; Humans ; Microscopy, Electron ; Microscopy, Electron, Transmission ; SARS-CoV-2 ; Temperature
    Sprache Englisch
    Erscheinungsdatum 2021-06-18
    Erscheinungsland India
    Dokumenttyp Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.IJMR_4264_20
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Development of

    Choudhary, Manohar Lal / Vipat, Veena / Jadhav, Sheetal / Basu, Atanu / Cherian, Sarah / Abraham, Priya / Potdar, Varsha A

    The Indian journal of medical research

    2020  Band 151, Heft 2 & 3, Seite(n) 251–254

    Mesh-Begriff(e) Betacoronavirus ; COVID-19 ; Clinical Laboratory Techniques ; Coronavirus ; Coronavirus Infections ; India ; Pandemics ; Pneumonia, Viral ; RNA ; Reverse Transcriptase Polymerase Chain Reaction ; SARS Virus/genetics ; SARS-CoV-2
    Chemische Substanzen RNA (63231-63-0)
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-04-03
    Erscheinungsland India
    Dokumenttyp Letter ; Comment
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    DOI 10.4103/ijmr.IJMR_671_20
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Perspectives for repurposing drugs for the coronavirus disease 2019

    Cherian, Sarah S / Agrawal, Megha / Basu, Atanu / Abraham, Priya / Gangakhedkar, Raman R / Bhargava, Balram

    Indian J Med Res

    Abstract: The newly emerged 2019 novel coronavirus (CoV), named as severe acute respiratory syndrome CoV-2 (SARS-CoV-2), like SARS-CoV (now, SARS-CoV-1) and Middle East respiratory syndrome CoV (MERS-CoV), has been associated with high infection rates with over 36, ...

    Abstract The newly emerged 2019 novel coronavirus (CoV), named as severe acute respiratory syndrome CoV-2 (SARS-CoV-2), like SARS-CoV (now, SARS-CoV-1) and Middle East respiratory syndrome CoV (MERS-CoV), has been associated with high infection rates with over 36,405 deaths. In the absence of approved marketed drugs against coronaviruses, the treatment and management of this novel CoV disease (COVID-19) worldwide is a challenge. Drug repurposing that has emerged as an effective drug discovery approach from earlier approved drugs could reduce the time and cost compared to de novo drug discovery. Direct virus-targeted antiviral agents target specific nucleic acid or proteins of the virus while host-based antivirals target either the host innate immune responses or the cellular machineries that are crucial for viral infection. Both the approaches necessarily interfere with viral pathogenesis. Here we summarize the present status of both virus-based and host-based drug repurposing perspectives for coronaviruses in general and the SARS-CoV-2 in particular.
    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #32317408
    Datenquelle COVID19

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