Article: Recent advances in infectious disease research using cryo-electron tomography.
Frontiers in molecular biosciences
2024 Volume 10, Page(s) 1296941
Abstract: With the increasing spread of infectious diseases worldwide, there is an urgent need for novel strategies to combat them. Cryogenic sample electron microscopy (cryo-EM) techniques, particularly electron tomography (cryo-ET), have revolutionized the field ...
| Abstract | With the increasing spread of infectious diseases worldwide, there is an urgent need for novel strategies to combat them. Cryogenic sample electron microscopy (cryo-EM) techniques, particularly electron tomography (cryo-ET), have revolutionized the field of infectious disease research by enabling multiscale observation of biological structures in a near-native state. This review highlights the recent advances in infectious disease research using cryo-ET and discusses the potential of this structural biology technique to help discover mechanisms of infection in native environments and guiding in the right direction for future drug discovery. |
|---|---|
| Language | English |
| Publishing date | 2024-01-15 |
| Publishing country | Switzerland |
| Document type | Journal Article ; Review |
| ZDB-ID | 2814330-9 |
| ISSN | 2296-889X |
| ISSN | 2296-889X |
| DOI | 10.3389/fmolb.2023.1296941 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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