LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Suchergebnis

Treffer 1 - 10 von insgesamt 67

Suchoptionen

  1. Buch ; Dissertation / Habilitation: Einfluss der Mannheimer Referenztafel auf die Reliabilität des SES-CD

    Weiss, Tobias / Belle, Sebastian

    2021  

    Körperschaft Universität Heidelberg
    Verfasserangabe vorgelegt von Tobias Weiss ; Referent: Priv.-Doz. med. Belle
    Sprache Deutsch
    Umfang 65 Seiten, Diagramme, Illustrationen, 30 cm
    Erscheinungsort Heidelberg
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Dissertation, Ruprecht-Karls-Universität Heidelberg, 2021
    HBZ-ID HT021221577
    Datenquelle Katalog ZB MED Medizin, Gesundheit

    Zusatzmaterialien

    Kategorien

  2. Buch ; Dissertation / Habilitation: Die Behandlung von benignen Gallengangstenosen mittels Stenting

    Greiner, Lisa / Belle, Sebastian

    eine retrospektive Datenanalyse

    2021  

    Körperschaft Universität Heidelberg
    Verfasserangabe vorgelegt von Lisa Greiner ; Referent: Priv.-Doz. Dr. med. Sebastian Belle
    Sprache Deutsch
    Umfang 90 Blätter, Diagramme, Illustrationen, 30 cm
    Erscheinungsort Heidelberg
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Dissertation, Ruprecht-Karls-Universität Heidelberg, 2021
    HBZ-ID HT021229103
    Datenquelle Katalog ZB MED Medizin, Gesundheit

    Zusatzmaterialien

    Kategorien

  3. Buch ; Dissertation / Habilitation: Endoskopische Resektion flacher und sessiler Läsionen des Kolorektums

    Hauf, Corinna / Belle, Sebastian

    Rezidivauftreten - synchrone Läsionen - Nachsorgeverhalten : eine multiperspektivische Betrachtung

    2019  

    Körperschaft Universität Heidelberg
    Verfasserangabe vorgelegt von Corinna Stefanie Hauf, Referent: PD Dr. med. Sebastian Belle
    Sprache Deutsch
    Umfang 94 Blätter, Diagramme, 30 cm
    Erscheinungsort Heidelberg
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Dissertation, Ruprecht-Karls-Universität zu Heidelberg, 2020
    HBZ-ID HT020893650
    Datenquelle Katalog ZB MED Medizin, Gesundheit

    Zusatzmaterialien

    Kategorien

  4. Artikel: Endoscopic Decompression in Colonic Distension.

    Belle, Sebastian

    Visceral medicine

    2021  Band 37, Heft 2, Seite(n) 142–148

    Abstract: Background: Acute colonic distension is a medical emergency with high morbidity and mortality. Clinically important causes of colonic distension are acute colonic pseudo-obstruction, colonic volvulus, and malignant obstruction. Endoscopic decompression ... ...

    Abstract Background: Acute colonic distension is a medical emergency with high morbidity and mortality. Clinically important causes of colonic distension are acute colonic pseudo-obstruction, colonic volvulus, and malignant obstruction. Endoscopic decompression is one established therapeutic strategy.
    Summary: This therapeutic review will give an overview of possible therapeutic strategies based on the recently published literature, focusing on endoscopic decompression and summarizing the other therapeutic possibilities. The review discusses separately the therapeutic options of acute colonic pseudo-obstruction, colonic volvulus, and malignant obstruction, providing an evidence-based orientation for clinical use.
    Key messages: Endoscopic decompression of colonic distension is an established therapy with high clinical success. The technique and its position in the therapy sequence differ depending on the medical condition, the trigger of the colonic distension, and the local expertise.
    Sprache Englisch
    Erscheinungsdatum 2021-02-11
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2850733-2
    ISSN 2297-475X ; 2297-4725
    ISSN (online) 2297-475X
    ISSN 2297-4725
    DOI 10.1159/000514799
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  5. Buch ; Dissertation / Habilitation: Identifikation von immunogenen T-Zellepitopen aus der schweren Kette der Immunglobuline beim Multiplen Myelom

    Belle, Sebastian

    2007  

    Verfasserangabe vorgelegt von Sebastian Belle
    Sprache Deutsch
    Umfang 117 Bl. : graph. Darst.
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Heidelberg, Univ., Diss., 2008
    HBZ-ID HT015534605
    Datenquelle Katalog ZB MED Medizin, Gesundheit

    Zusatzmaterialien

    Kategorien

  6. Artikel ; Online: Refuting Marine Aquaculture Myths, Unfounded Criticisms, and Assumptions

    Zajicek, Paul / Corbin, John / Belle, Sebastian / Rheault, Robert

    Reviews in Fisheries Science & Aquaculture. 2023 Jan. 2, v. 31, no. 1 p.1-28

    2023  

    Abstract: Sustainable domestic aquaculture development is a critical component to achieving greater U.S. seafood security in the future, yet detrimental allegations have corrupted public support. A variety of longstanding and inaccurate myths and assumptions ... ...

    Abstract Sustainable domestic aquaculture development is a critical component to achieving greater U.S. seafood security in the future, yet detrimental allegations have corrupted public support. A variety of longstanding and inaccurate myths and assumptions directed at offshore aquaculture farming and its regulation have been foisted on the public. This paper refutes the most prevalent critiques by reviewing current policies, regulations, research and industry production practices. These criticisms include: inadequate regulatory oversight; portrayal of farms as being high density factories unconcerned by food waste, untreated discharge, use of antibiotic and antifungal treatments; entanglement of marine mammals; impacts on wild stocks and habitats; use of feed additives to pigment fish flesh; unsustainable use of fish meal in feed formulations; potential market disruption by producing cheap, low quality products; and commercial farms and commercial fishers cannot coexist as for-profit businesses. Marine aquaculture is not risk-free in terms of potential environmental, economic, social, and cultural impacts and challenges remain to achieve a sustainable industry. These challenges are well known and addressable by the U.S. and global research community. Current offshore farming realities bode well for the future: 1) there is a clear global imperative to sustainably produce more seafood to meet growing demand and the U.S. has the marine resources to become a major exporter, if U.S. law can be amended to grant offshore farmers a property right or security of tenure for sites in federal waters; 2) U.S. ocean farmers work within a very complex and effective legal, regulatory, science-driven environment to anticipate and mitigate potential impacts; 3) farm level management decisions and federal and state regulatory frameworks have worked together to bring about environmentally friendly siting, operational, and production outcomes, and 4) the farming community and its advocates in government, universities, and industry recognize it is essential to reach out to decision-makers and the interested public, as well as critics, with the latest research and empirical results to present an accurate picture of risks and rewards to development.
    Schlagwörter antibiotics ; fish ; fish meal ; food waste ; industry ; mariculture ; markets ; seafoods ; Aquaculture ; science ; regulation ; policy ; production practice
    Sprache Englisch
    Erscheinungsverlauf 2023-0102
    Umfang p. 1-28.
    Erscheinungsort Taylor & Francis
    Dokumenttyp Artikel ; Online
    ZDB-ID 2772853-5
    ISSN 2330-8257 ; 2330-8249
    ISSN (online) 2330-8257
    ISSN 2330-8249
    DOI 10.1080/23308249.2021.1980767
    Datenquelle NAL Katalog (AGRICOLA)

    Zusatzmaterialien

    Kategorien

  7. Artikel ; Online: Auswirkungsanalyse einer neuen, sektorenübergreifenden Erbringung bisher stationärer endoskopischer gastroenterologischer Leistungen entsprechend §115f SGB V (Hybrid-DRG): Zuordnungsmatrix und Kostenanalyse.

    Rathmayer, Markus / Belle, Sebastian / Heinlein, Wolfgang / Dollhopf, Markus / Braun, Martin / Albert, Jörg G

    Zeitschrift fur Gastroenterologie

    2024  Band 62, Heft 5, Seite(n) 705–722

    Abstract: Background: With the introduction of §115f SGB V, the prerequisites for "sector-equal remuneration" ('Hybrid DRG') have been created. In an impact analysis, we assigned inpatient gastroenterological endoscopic (GAEN) cases in a matrix of future hybrid ... ...

    Titelübersetzung Impact Analysis of a new, Cross-sector Service Provision of Gastroenterologic Endoscopic Services in Accordance with 115f SGB V (Hybrid-DRG): Allocation Matrix and Cost Analysis.
    Abstract Background: With the introduction of §115f SGB V, the prerequisites for "sector-equal remuneration" ('Hybrid DRG') have been created. In an impact analysis, we assigned inpatient gastroenterological endoscopic (GAEN) cases in a matrix of future hybrid DRG versus outpatient surgery (AOP) or inpatient treatment.
    Methods: In selected DRGs (G47B, G67A, G67B, G67C, G71Z, H41D, H41E) an allocation matrix of GAEN cases was created on medical grounds. For this purpose, service groups from the DGVS service catalog ('Leistungskatalog') were assigned to the groups: 'Hybrid-DRG', 'AOP' and 'Inpatient' by a group of experts based on the DGVS position paper. Cost data from the DGVS-DRG project for the 2022 data year from 36 InEK calculation hospitals with a total of 232,476 GAEN cases were evaluated.
    Results: 26 service groups from the DGVS service catalog were assigned to a "Hybrid-DRG", 24 to the "inpatient" group, and 12 to the "AOP" group. 7 performance groups were splitted "depending on the OPS code" and classified at this level. Cases with additional fees were excluded from a hybrid DRG because these cannot be agreed there.The cost analysis shows that services that are already in the AOP have a similar cost level to services that have been classified as 'Hybrid-DRG'. With the cost calculation, a cost level could be presented for the hybrid DRGs formed.
    Conclusion: Based on clearly defined structural, procedural and personnel requirements, services from suitable DRGs can be transferred to a hybrid DRG. Assigning services without the involvement of clinical experts seems extremely difficult. Case assignment based on arbitrary contextual factors increases complexity without demonstrably increasing the quality of the assignment and needs to be further developed. A cost analysis can be derived from the known inpatient costs and must serve as the basis for the 2025 Hybrid DRG catalog.
    Mesh-Begriff(e) Diagnosis-Related Groups/economics ; Germany ; Humans ; Endoscopy, Gastrointestinal/economics ; Health Care Costs/statistics & numerical data ; Costs and Cost Analysis ; Gastroenterology/economics ; National Health Programs/economics
    Sprache Deutsch
    Erscheinungsdatum 2024-04-15
    Erscheinungsland Germany
    Dokumenttyp English Abstract ; Journal Article
    ZDB-ID 201387-3
    ISSN 1439-7803 ; 0172-8504 ; 0044-2771
    ISSN (online) 1439-7803
    ISSN 0172-8504 ; 0044-2771
    DOI 10.1055/a-2292-9766
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  8. Artikel ; Online: The role of the multidisciplinary tumor board after endoscopic resection of malignant tumors: is it worth it?

    Kouladouros, Konstantinos / Centner, Maximilian / Reissfelder, Christoph / Belle, Sebastian / Kähler, Georg

    Surgical endoscopy

    2023  Band 38, Heft 2, Seite(n) 607–613

    Abstract: Objectives: The value of multidisciplinary tumor boards (MTBs) in the treatment of gastrointestinal cancer patients is well known. Most of the current evidence focuses on advanced cancer cases, whereas little is known about the effect of MTBs on early ... ...

    Abstract Objectives: The value of multidisciplinary tumor boards (MTBs) in the treatment of gastrointestinal cancer patients is well known. Most of the current evidence focuses on advanced cancer cases, whereas little is known about the effect of MTBs on early tumors, especially after endoscopic resection. The aim of our study is to evaluate the value of the MTB after endoscopic resection of malignant tumors of the gastrointestinal tract.
    Methods: We retrospectively analyzed all endoscopically resected malignant tumors in our department between 2011 and 2019, focusing on the existence of an MDT recommendation after endoscopic resection, the MDT adherence to the current guidelines, and the implementation of the recommendation by the patients.
    Results: We identified 198 patients fulfilling our inclusion criteria, of whom 168 (85%) were discussed in the MDT after endoscopic resection. In total, 155 of the recommendations (92%) were in accordance with the current guidelines, and 147 (88%) of them were implemented by the patients. The MDT discussion itself did not influence the overall survival, whereas the implementation of the MTB recommendation was associated with a significantly better prognosis. Deviations of the MDT recommendation from the guidelines had no effect on the overall survival.
    Conclusions: The discussion of endoscopically resected malignant tumors in the MTB is crucial for the treatment of patients with this type of cancer, since the implementation of the MTB recommendation, even if it deviates from the current guidelines, improves the prognosis.
    Mesh-Begriff(e) Humans ; Retrospective Studies ; Endoscopy ; Gastrointestinal Neoplasms/surgery ; Dissection ; Endoscopic Mucosal Resection ; Treatment Outcome ; Stomach Neoplasms/surgery
    Sprache Englisch
    Erscheinungsdatum 2023-11-22
    Erscheinungsland Germany
    Dokumenttyp Journal Article
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-023-10555-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

  9. Artikel ; Online: Deep Learning by Domain Transfer for Early Tumor Detection in the Urinary Bladder

    Eixelberger Thomas / Maisch Philip / Kruck Stephan / Belle Sebastian / Kriegmair Maximilian / Bolenz Christian / Wittenberg Thomas

    Current Directions in Biomedical Engineering, Vol 9, Iss 1, Pp 53-

    2023  Band 56

    Abstract: Background: Bladder cancer (BCa) is the second most common genitourinary malignancy and has a mortality of 165,000 deaths p.a. The diagnosis of BCa is mostly carried out using cystoscopy - the visual examination of the urinary bladder with an endoscope. ... ...

    Abstract Background: Bladder cancer (BCa) is the second most common genitourinary malignancy and has a mortality of 165,000 deaths p.a. The diagnosis of BCa is mostly carried out using cystoscopy - the visual examination of the urinary bladder with an endoscope. White light cystoscopy is currently considered as gold standard for the diagnosis. Nevertheless, especially flat, small or weakly textured lesions, are very difficult to detect and diagnose. Objective: With the advent of deep learning and already commercially available systems for the detection of adenomas in colonoscopy, it is investigated how such a system - for colonoscopy - performs if retrained and tested with cystoscopy images. Methods: A deep neural network with a YOLOv7-tiny architecture was pre-trained on 35,699 colonoscopy images (partially from Mannheim), yielding a precision = 0.92, sensitivity = 0.90, F1 = 0.91 on public colonoscopy data collections. Results: Testing this adenomadetection network with cystoscopy images from three sources (Ulm, Erlangen, Pforzheim), F1 scores in the range of 0.67 to 0.74 could be achieved. The network was then retrained with 12,066 cystoscopy images (from Mannheim), yielding improved F1 scores in the range of 0.78 to 0.85. Conclusion: It could be shown that a deep learning network for adenoma detection in colonoscopy is ad-hoc able to detect approximately 75% of the lesions in the urinary bladder in cystoscopy images, suggesting that these lesions have a similar appearance. After retraining the network with additional cystoscopy data, the performance for urinary lesion detection could be improved, indicating that a domain-shift with adequate additional data is feasible.
    Schlagwörter yolo networks ; deep learning ; domain transfer ; urinary bladder cancer ; early detection ; Medicine ; R
    Thema/Rubrik (Code) 006
    Sprache Englisch
    Erscheinungsdatum 2023-09-01T00:00:00Z
    Verlag De Gruyter
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Zusatzmaterialien

    Kategorien

  10. Artikel ; Online: Endoskopisches Komplikationsmanagment nach bariatrischen Operationen mit dem Fokus auf die aktuellen endoskopischen Therapien.

    Belle, Sebastian / Kouladouros, Konstantinos / Kähler, Georg

    Zentralblatt fur Chirurgie

    2022  Band 147, Heft 6, Seite(n) 539–546

    Abstract: In bariatric surgery, complications are rare. Most of the complications can be managed by endoscopy. Rare complications impose a challenge in everyday clinical work. To optimally treat the complications and to minimise the harm to the patient it is ... ...

    Titelübersetzung Management of Endoscopic Complications after Bariatric Surgery: Focus on Current Endoscopic Therapy.
    Abstract In bariatric surgery, complications are rare. Most of the complications can be managed by endoscopy. Rare complications impose a challenge in everyday clinical work. To optimally treat the complications and to minimise the harm to the patient it is important to implement complication management. This review gives an overview of relevant bariatric complications and endoscopic therapy strategies, focusing on published literature of the last five years. This manuscript could be a starting point for complication management in the clinic.
    Mesh-Begriff(e) Humans ; Bariatric Surgery/adverse effects
    Sprache Deutsch
    Erscheinungsdatum 2022-12-07
    Erscheinungsland Germany
    Dokumenttyp Review ; English Abstract ; Journal Article
    ZDB-ID 200935-3
    ISSN 1438-9592 ; 0044-409X
    ISSN (online) 1438-9592
    ISSN 0044-409X
    DOI 10.1055/a-1962-6910
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

Zum Seitenanfang