Artikel ; Online: Endovascular treatment of 346 middle cerebral artery aneurysms: results of a 16-year single-center experience.
2015 Band 76, Heft 1, Seite(n) 54–60; discussion 60–1
Abstract: Background: The endovascular treatment of middle cerebral artery (MCA) aneurysms has been controversial because of the frequency of complex anatomy and the relative ease of surgical clipping in this location.: Objective: To present a large single- ... ...
Abstract | Background: The endovascular treatment of middle cerebral artery (MCA) aneurysms has been controversial because of the frequency of complex anatomy and the relative ease of surgical clipping in this location. Objective: To present a large single-center experience with the endovascular treatment of MCA aneurysms. Methods: The neurointerventional database at our institution was reviewed for all endovascular treatments of MCA aneurysms. Demographics, aneurysm characteristics, treatment modality, intraprocedural hemorrhagic and thromboembolic events, 30-day neurological events, and follow-up angiographic studies were recorded. Results: From December 1996 to April 2013, 292 patients underwent endovascular treatment of 346 MCA aneurysms. Of these, 341 (98.6%) were successfully completed. Balloon neck remodeling was used in 230 procedures (66.5%). Ninety-five procedures (27.4%) were for ruptured aneurysms. The rate of intraprocedural hemorrhage was 2.6% (9 of 346). The overall rate of intraprocedural thromboembolic events was 13.6% (47 of 346), significantly more common in patients with acute subarachnoid hemorrhage (27.4%; P < .001). The 30-day major (modified Rankin Scale score > 2) neurological event rate was 2.9% (10 of 346), significantly more common in patients with subarachnoid hemorrhage (8.4%) compared with those without (0.8%; P < .001). The rate of complete or near-complete aneurysm occlusion at was 90.6% ≥ 6 months and 91.8% at ≥ 2 years, with an average of 24 months of follow-up available for 247 procedures. Conclusion: Endovascular treatment of MCA aneurysms can be safe and effective. However, it is associated with a high asymptomatic thromboembolic event rate that is more frequent in the setting of acute subarachnoid hemorrhage. |
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Mesh-Begriff(e) | Aneurysm, Ruptured/complications ; Aneurysm, Ruptured/therapy ; Embolization, Therapeutic/adverse effects ; Endovascular Procedures/adverse effects ; Female ; Follow-Up Studies ; Humans ; Intracranial Aneurysm/complications ; Intracranial Aneurysm/therapy ; Male ; Middle Aged ; Retrospective Studies ; Stents ; Subarachnoid Hemorrhage/epidemiology ; Subarachnoid Hemorrhage/therapy ; Thromboembolism/epidemiology ; Thromboembolism/therapy ; Treatment Outcome | ||||||||||
Schlagwörter | covid19 | ||||||||||
Sprache | Englisch | ||||||||||
Erscheinungsdatum | 2015-01 | ||||||||||
Erscheinungsland | United States | ||||||||||
Dokumenttyp | Journal Article | ||||||||||
ZDB-ID | 135446-2 | ||||||||||
ISSN | 1524-4040 ; 0148-396X | ||||||||||
ISSN (online) | 1524-4040 | ||||||||||
ISSN | 0148-396X | ||||||||||
DOI | 10.1227/NEU.0000000000000562 | ||||||||||
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Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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