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  1. Artikel ; Online: Endogenous opiates and behavior: 2021.

    Bodnar, Richard J

    Peptides

    2023  Band 164, Seite(n) 171004

    Abstract: This paper is the forty-fourth consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2021 that studied the behavioral effects of molecular, pharmacological and ...

    Abstract This paper is the forty-fourth consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2021 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides and receptors as well as effects of opioid/opiate agonizts and antagonists. The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors (1), the roles of these opioid peptides and receptors in pain and analgesia in animals (2) and humans (3), opioid-sensitive and opioid-insensitive effects of nonopioid analgesics (4), opioid peptide and receptor involvement in tolerance and dependence (5), stress and social status (6), learning and memory (7), eating and drinking (8), drug abuse and alcohol (9), sexual activity and hormones, pregnancy, development and endocrinology (10), mental illness and mood (11), seizures and neurologic disorders (12), electrical-related activity and neurophysiology (13), general activity and locomotion (14), gastrointestinal, renal and hepatic functions (15), cardiovascular responses (16), respiration and thermoregulation (17), and immunological responses (18).
    Mesh-Begriff(e) Animals ; Humans ; Opioid Peptides/pharmacology ; Receptors, Opioid/physiology ; Analgesics, Opioid/pharmacology ; Learning/physiology ; Pain/drug therapy
    Chemische Substanzen Opioid Peptides ; Receptors, Opioid ; Analgesics, Opioid
    Sprache Englisch
    Erscheinungsdatum 2023-03-27
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 769028-9
    ISSN 1873-5169 ; 0196-9781
    ISSN (online) 1873-5169
    ISSN 0196-9781
    DOI 10.1016/j.peptides.2023.171004
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Endogenous opiates and behavior: 2022.

    Bodnar, Richard J

    Peptides

    2023  Band 169, Seite(n) 171095

    Abstract: This paper is the forty-fifth consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2022 that studied the behavioral effects of molecular, pharmacological and ... ...

    Abstract This paper is the forty-fifth consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2022 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides and receptors as well as effects of opioid/opiate agonists and antagonists. The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors (1), the roles of these opioid peptides and receptors in pain and analgesia in animals (2) and humans (3), opioid-sensitive and opioid-insensitive effects of nonopioid analgesics (4), opioid peptide and receptor involvement in tolerance and dependence (5), stress and social status (6), learning and memory (7), eating and drinking (8), drug abuse and alcohol (9), sexual activity and hormones, pregnancy, development and endocrinology (10), mental illness and mood (11), seizures and neurologic disorders (12), electrical-related activity and neurophysiology (13), general activity and locomotion (14), gastrointestinal, renal and hepatic functions (15), cardiovascular responses (16), respiration and thermoregulation (17), and immunological responses (18).
    Mesh-Begriff(e) Animals ; Humans ; Female ; Pregnancy ; Opioid Peptides/pharmacology ; Analgesics, Opioid ; Analgesia ; Analgesics, Non-Narcotic ; Drug Tolerance
    Chemische Substanzen Opioid Peptides ; Analgesics, Opioid ; Analgesics, Non-Narcotic
    Sprache Englisch
    Erscheinungsdatum 2023-09-12
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 769028-9
    ISSN 1873-5169 ; 0196-9781
    ISSN (online) 1873-5169
    ISSN 0196-9781
    DOI 10.1016/j.peptides.2023.171095
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Endogenous opiates and behavior: 2020.

    Bodnar, Richard J

    Peptides

    2022  Band 151, Seite(n) 170752

    Abstract: This paper is the forty-third consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2020 that studied the behavioral effects of molecular, pharmacological and ... ...

    Abstract This paper is the forty-third consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2020 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides and receptors as well as effects of opioid/opiate agonists and antagonists. The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors (1), the roles of these opioid peptides and receptors in pain and analgesia in animals (2) and humans (3), opioid-sensitive and opioid-insensitive effects of nonopioid analgesics (4), opioid peptide and receptor involvement in tolerance and dependence (5), stress and social status (6), learning and memory (7), eating and drinking (8), drug abuse and alcohol (9), sexual activity and hormones, pregnancy, development and endocrinology (10), mental illness and mood (11), seizures and neurologic disorders (12), electrical-related activity and neurophysiology (13), general activity and locomotion (14), gastrointestinal, renal and hepatic functions (15), cardiovascular responses (16), respiration and thermoregulation (17), and immunological responses (18).
    Mesh-Begriff(e) Analgesics, Opioid/pharmacology ; Animals ; Female ; Learning/physiology ; Opioid Peptides/pharmacology ; Pain/drug therapy ; Pregnancy ; Receptors, Opioid/agonists
    Chemische Substanzen Analgesics, Opioid ; Opioid Peptides ; Receptors, Opioid
    Sprache Englisch
    Erscheinungsdatum 2022-01-31
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 769028-9
    ISSN 1873-5169 ; 0196-9781
    ISSN (online) 1873-5169
    ISSN 0196-9781
    DOI 10.1016/j.peptides.2022.170752
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Endogenous opiates and behavior: 2019.

    Bodnar, Richard J

    Peptides

    2021  Band 141, Seite(n) 170547

    Abstract: This paper is the forty-second consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2019 that studied the behavioral effects of molecular, pharmacological and ...

    Abstract This paper is the forty-second consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2019 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides and receptors as well as effects of opioid/opiate agonists and antagonists. The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors (1), the roles of these opioid peptides and receptors in pain and analgesia in animals (2) and humans (3), opioid-sensitive and opioid-insensitive effects of nonopioid analgesics (4), opioid peptide and receptor involvement in tolerance and dependence (5), stress and social status (6), learning and memory (7), eating and drinking (8), drug abuse and alcohol (9), sexual activity and hormones, pregnancy, development and endocrinology (10), mental illness and mood (11), seizures and neurologic disorders (12), electrical-related activity and neurophysiology (13), general activity and locomotion (14), gastrointestinal, renal and hepatic functions (15), cardiovascular responses (16), respiration and thermoregulation (17), and immunological responses (18).
    Mesh-Begriff(e) Analgesics, Opioid/pharmacology ; Animals ; Cancer Pain/drug therapy ; Cancer Pain/genetics ; Chronic Pain/drug therapy ; Ethanol/pharmacology ; Female ; Humans ; Memory/drug effects ; Memory/physiology ; Opioid Peptides/pharmacology ; Opioid Peptides/physiology ; Pain, Postoperative/drug therapy ; Pregnancy ; Receptors, Opioid/agonists ; Receptors, Opioid/physiology ; Sexual Behavior/physiology ; Social Status ; Stress, Psychological/physiopathology ; Substance-Related Disorders/etiology ; Substance-Related Disorders/genetics
    Chemische Substanzen Analgesics, Opioid ; Opioid Peptides ; Receptors, Opioid ; Ethanol (3K9958V90M)
    Sprache Englisch
    Erscheinungsdatum 2021-04-05
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 769028-9
    ISSN 1873-5169 ; 0196-9781
    ISSN (online) 1873-5169
    ISSN 0196-9781
    DOI 10.1016/j.peptides.2021.170547
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

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  5. Artikel: Endogenous opiates and behavior: 2020

    Bodnar, Richard J.

    Peptides. 2022 May, v. 151

    2022  

    Abstract: This paper is the forty-third consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2020 that studied the behavioral effects of molecular, pharmacological and ... ...

    Abstract This paper is the forty-third consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2020 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides and receptors as well as effects of opioid/opiate agonists and antagonists. The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors (1), the roles of these opioid peptides and receptors in pain and analgesia in animals (2) and humans (3), opioid-sensitive and opioid-insensitive effects of nonopioid analgesics (4), opioid peptide and receptor involvement in tolerance and dependence (5), stress and social status (6), learning and memory (7), eating and drinking (8), drug abuse and alcohol (9), sexual activity and hormones, pregnancy, development and endocrinology (10), mental illness and mood (11), seizures and neurologic disorders (12), electrical-related activity and neurophysiology (13), general activity and locomotion (14), gastrointestinal, renal and hepatic functions (15), cardiovascular responses (16), respiration and thermoregulation (17), and immunological responses (18).
    Schlagwörter alcohols ; analgesia ; analgesics ; behavior disorders ; drug abuse ; emotions ; gastrointestinal system ; genetic engineering ; locomotion ; memory ; narcotics ; opioid peptides ; pain ; pregnancy ; socioeconomic status ; thermoregulation
    Sprache Englisch
    Erscheinungsverlauf 2022-05
    Erscheinungsort Elsevier Inc.
    Dokumenttyp Artikel
    ZDB-ID 769028-9
    ISSN 1873-5169 ; 0196-9781
    ISSN (online) 1873-5169
    ISSN 0196-9781
    DOI 10.1016/j.peptides.2022.170752
    Datenquelle NAL Katalog (AGRICOLA)

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  6. Artikel ; Online: Endogenous Opiates and Behavior: 2018.

    Bodnar, Richard J

    Peptides

    2020  Band 132, Seite(n) 170348

    Abstract: This paper is the forty-first consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2018 that studied the behavioral effects of molecular, pharmacological and ... ...

    Abstract This paper is the forty-first consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2018 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides and receptors as well as effects of opioid/opiate agonists and antagonists. The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors (2), the roles of these opioid peptides and receptors in pain and analgesia in animals (3) and humans (4), opioid-sensitive and opioid-insensitive effects of nonopioid analgesics (5), opioid peptide and receptor involvement in tolerance and dependence (6), stress and social status (7), learning and memory (8), eating and drinking (9), drug abuse and alcohol (10), sexual activity and hormones, pregnancy, development and endocrinology (11), mental illness and mood (12), seizures and neurologic disorders (13), electrical-related activity and neurophysiology (14), general activity and locomotion (15), gastrointestinal, renal and hepatic functions (16), cardiovascular responses (17), respiration and thermoregulation (18), and immunological responses (19).
    Mesh-Begriff(e) Analgesics, Opioid/pharmacology ; Animals ; Behavior/drug effects ; Humans ; Learning/physiology ; Mental Disorders/drug therapy ; Mental Disorders/metabolism ; Narcotic Antagonists/pharmacology ; Opioid Peptides/agonists ; Opioid Peptides/antagonists & inhibitors ; Opioid Peptides/metabolism ; Opioid Peptides/pharmacology ; Pain/drug therapy ; Pain/metabolism ; Receptors, Opioid/agonists
    Chemische Substanzen Analgesics, Opioid ; Narcotic Antagonists ; Opioid Peptides ; Receptors, Opioid
    Sprache Englisch
    Erscheinungsdatum 2020-06-20
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 769028-9
    ISSN 1873-5169 ; 0196-9781
    ISSN (online) 1873-5169
    ISSN 0196-9781
    DOI 10.1016/j.peptides.2020.170348
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: 2018 Gayle A. Olson And Richard D. Olson Prize Vladimir A. Kashkin.

    Bodnar, Richard J

    Peptides

    2020  Band 126, Seite(n) 170252

    Mesh-Begriff(e) Analgesics/history ; Analgesics/therapeutic use ; Awards and Prizes ; History, 21st Century ; Humans ; Morphine Dependence/prevention & control ; Peptide Fragments/history ; Peptide Fragments/therapeutic use
    Chemische Substanzen Analgesics ; Peptide Fragments
    Sprache Englisch
    Erscheinungsdatum 2020-01-10
    Erscheinungsland United States
    Dokumenttyp Biography ; Editorial ; Historical Article
    ZDB-ID 769028-9
    ISSN 1873-5169 ; 0196-9781
    ISSN (online) 1873-5169
    ISSN 0196-9781
    DOI 10.1016/j.peptides.2020.170252
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel: Endogenous opiates and behavior: 2019

    Bodnar, Richard J

    Peptides. 2021 July, v. 141

    2021  

    Abstract: This paper is the forty-second consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2019 that studied the behavioral effects of molecular, pharmacological and ...

    Abstract This paper is the forty-second consecutive installment of the annual anthological review of research concerning the endogenous opioid system, summarizing articles published during 2019 that studied the behavioral effects of molecular, pharmacological and genetic manipulation of opioid peptides and receptors as well as effects of opioid/opiate agonists and antagonists. The review is subdivided into the following specific topics: molecular-biochemical effects and neurochemical localization studies of endogenous opioids and their receptors (1), the roles of these opioid peptides and receptors in pain and analgesia in animals (2) and humans (3), opioid-sensitive and opioid-insensitive effects of nonopioid analgesics (4), opioid peptide and receptor involvement in tolerance and dependence (5), stress and social status (6), learning and memory (7), eating and drinking (8), drug abuse and alcohol (9), sexual activity and hormones, pregnancy, development and endocrinology (10), mental illness and mood (11), seizures and neurologic disorders (12), electrical-related activity and neurophysiology (13), general activity and locomotion (14), gastrointestinal, renal and hepatic functions (15), cardiovascular responses (16), respiration and thermoregulation (17), and immunological responses (18).
    Schlagwörter alcohols ; analgesia ; analgesics ; behavior disorders ; drug abuse ; emotions ; gastrointestinal system ; genetic engineering ; locomotion ; memory ; narcotics ; opioid peptides ; pain ; pregnancy ; socioeconomic status ; thermoregulation
    Sprache Englisch
    Erscheinungsverlauf 2021-07
    Erscheinungsort Elsevier Inc.
    Dokumenttyp Artikel
    Anmerkung NAL-AP-2-clean
    ZDB-ID 769028-9
    ISSN 1873-5169 ; 0196-9781
    ISSN (online) 1873-5169
    ISSN 0196-9781
    DOI 10.1016/j.peptides.2021.170547
    Datenquelle NAL Katalog (AGRICOLA)

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  9. Artikel ; Online: Opioid addiction.

    Bodnar, Richard J

    Peptides

    2019  Band 116, Seite(n) 68–70

    Mesh-Begriff(e) Analgesics, Opioid/therapeutic use ; Humans ; Opioid-Related Disorders/drug therapy ; Opioid-Related Disorders/physiopathology
    Chemische Substanzen Analgesics, Opioid
    Sprache Englisch
    Erscheinungsdatum 2019-05-11
    Erscheinungsland United States
    Dokumenttyp Editorial
    ZDB-ID 769028-9
    ISSN 1873-5169 ; 0196-9781
    ISSN (online) 1873-5169
    ISSN 0196-9781
    DOI 10.1016/j.peptides.2019.04.010
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Endogenous opioid modulation of food intake and body weight: Implications for opioid influences upon motivation and addiction.

    Bodnar, Richard J

    Peptides

    2019  Band 116, Seite(n) 42–62

    Abstract: This review is part of a special issue dedicated to Opioid addiction, and examines the influential role of opioid peptides, opioid receptors and opiate drugs in mediating food intake and body weight control in rodents. This review postulates that opioid ... ...

    Abstract This review is part of a special issue dedicated to Opioid addiction, and examines the influential role of opioid peptides, opioid receptors and opiate drugs in mediating food intake and body weight control in rodents. This review postulates that opioid mediation of food intake was an example of "positive addictive" properties that provide motivational drives to maintain opioid-seeking behavior and that are not subject to the "negative addictive" properties associated with tolerance, dependence and withdrawal. Data demonstrate that opiate and opioid peptide agonists stimulate food intake through homeostatic activation of sensory, metabolic and energy-related In contrast, general, and particularly mu-selective, opioid receptor antagonists typically block these homeostatically-driven ingestive behaviors. Intake of palatable and hedonic food stimuli is inhibited by general, and particularly mu-selective, opioid receptor antagonists. The selectivity of specific opioid agonists to elicit food intake was confirmed through the use of opioid receptor antagonists and molecular knockdown (antisense) techniques incapacitating specific exons of opioid receptor genes. Further extensive evidence demonstrated that homeostatic and hedonic ingestive situations correspondingly altered the levels and expression of opioid peptides and opioid receptors. Opioid mediation of food intake was controlled by a distributed brain network intimately related to both the appetitive-consummatory sites implicated in food intake as well as sites intimately involved in reward and reinforcement. This emergent system appears to sustain the "positive addictive" properties providing motivational drives to maintain opioid-seeking behavior.
    Mesh-Begriff(e) Animals ; Body Weight/genetics ; Brain/metabolism ; Eating/genetics ; Feeding Behavior/drug effects ; Humans ; Motivation/genetics ; Narcotic Antagonists/therapeutic use ; Opioid Peptides/genetics ; Receptors, Opioid/genetics
    Chemische Substanzen Narcotic Antagonists ; Opioid Peptides ; Receptors, Opioid
    Sprache Englisch
    Erscheinungsdatum 2019-04-30
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 769028-9
    ISSN 1873-5169 ; 0196-9781
    ISSN (online) 1873-5169
    ISSN 0196-9781
    DOI 10.1016/j.peptides.2019.04.008
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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