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Artikel ; Online: The genome sequence of taurine cattle: a window to ruminant biology and evolution.

Elsik, Christine G / Tellam, Ross L / Worley, Kim C / Gibbs, Richard A / Muzny, Donna M / Weinstock, George M / Adelson, David L / Eichler, Evan E / Elnitski, Laura / Guigó, Roderic / Hamernik, Debora L / Kappes, Steve M / Lewin, Harris A / Lynn, David J / Nicholas, Frank W / Reymond, Alexandre / Rijnkels, Monique / Skow, Loren C / Zdobnov, Evgeny M /
Schook, Lawrence / Womack, James / Alioto, Tyler / Antonarakis, Stylianos E / Astashyn, Alex / Chapple, Charles E / Chen, Hsiu-Chuan / Chrast, Jacqueline / Câmara, Francisco / Ermolaeva, Olga / Henrichsen, Charlotte N / Hlavina, Wratko / Kapustin, Yuri / Kiryutin, Boris / Kitts, Paul / Kokocinski, Felix / Landrum, Melissa / Maglott, Donna / Pruitt, Kim / Sapojnikov, Victor / Searle, Stephen M / Solovyev, Victor / Souvorov, Alexandre / Ucla, Catherine / Wyss, Carine / Anzola, Juan M / Gerlach, Daniel / Elhaik, Eran / Graur, Dan / Reese, Justin T / Edgar, Robert C / McEwan, John C / Payne, Gemma M / Raison, Joy M / Junier, Thomas / Kriventseva, Evgenia V / Eyras, Eduardo / Plass, Mireya / Donthu, Ravikiran / Larkin, Denis M / Reecy, James / Yang, Mary Q / Chen, Lin / Cheng, Ze / Chitko-McKown, Carol G / Liu, George E / Matukumalli, Lakshmi K / Song, Jiuzhou / Zhu, Bin / Bradley, Daniel G / Brinkman, Fiona S L / Lau, Lilian P L / Whiteside, Matthew D / Walker, Angela / Wheeler, Thomas T / Casey, Theresa / German, J Bruce / Lemay, Danielle G / Maqbool, Nauman J / Molenaar, Adrian J / Seo, Seongwon / Stothard, Paul / Baldwin, Cynthia L / Baxter, Rebecca / Brinkmeyer-Langford, Candice L / Brown, Wendy C / Childers, Christopher P / Connelley, Timothy / Ellis, Shirley A / Fritz, Krista / Glass, Elizabeth J / Herzig, Carolyn T A / Iivanainen, Antti / Lahmers, Kevin K / Bennett, Anna K / Dickens, C Michael / Gilbert, James G R / Hagen, Darren E / Salih, Hanni / Aerts, Jan / Caetano, Alexandre R / Dalrymple, Brian / Garcia, Jose Fernando / Gill, Clare A / Hiendleder, Stefan G / Memili, Erdogan / Spurlock, Diane / Williams, John L / Alexander, Lee / Brownstein, Michael J / Guan, Leluo / Holt, Robert A / Jones, Steven J M / Marra, Marco A / Moore, Richard / Moore, Stephen S / Roberts, Andy / Taniguchi, Masaaki / Waterman, Richard C / Chacko, Joseph / Chandrabose, Mimi M / Cree, Andy / Dao, Marvin Diep / Dinh, Huyen H / Gabisi, Ramatu Ayiesha / Hines, Sandra / Hume, Jennifer / Jhangiani, Shalini N / Joshi, Vandita / Kovar, Christie L / Lewis, Lora R / Liu, Yih-Shin / Lopez, John / Morgan, Margaret B / Nguyen, Ngoc Bich / Okwuonu, Geoffrey O / Ruiz, San Juana / Santibanez, Jireh / Wright, Rita A / Buhay, Christian / Ding, Yan / Dugan-Rocha, Shannon / Herdandez, Judith / Holder, Michael / Sabo, Aniko / Egan, Amy / Goodell, Jason / Wilczek-Boney, Katarzyna / Fowler, Gerald R / Hitchens, Matthew Edward / Lozado, Ryan J / Moen, Charles / Steffen, David / Warren, James T / Zhang, Jingkun / Chiu, Readman / Schein, Jacqueline E / Durbin, K James / Havlak, Paul / Jiang, Huaiyang / Liu, Yue / Qin, Xiang / Ren, Yanru / Shen, Yufeng / Song, Henry / Bell, Stephanie Nicole / Davis, Clay / Johnson, Angela Jolivet / Lee, Sandra / Nazareth, Lynne V / Patel, Bella Mayurkumar / Pu, Ling-Ling / Vattathil, Selina / Williams, Rex Lee / Curry, Stacey / Hamilton, Cerissa / Sodergren, Erica / Wheeler, David A / Barris, Wes / Bennett, Gary L / Eggen, André / Green, Ronnie D / Harhay, Gregory P / Hobbs, Matthew / Jann, Oliver / Keele, John W / Kent, Matthew P / Lien, Sigbjørn / McKay, Stephanie D / McWilliam, Sean / Ratnakumar, Abhirami / Schnabel, Robert D / Smith, Timothy / Snelling, Warren M / Sonstegard, Tad S / Stone, Roger T / Sugimoto, Yoshikazu / Takasuga, Akiko / Taylor, Jeremy F / Van Tassell, Curtis P / Macneil, Michael D / Abatepaulo, Antonio R R / Abbey, Colette A / Ahola, Virpi / Almeida, Iassudara G / Amadio, Ariel F / Anatriello, Elen / Bahadue, Suria M / Biase, Fernando H / Boldt, Clayton R / Carroll, Jeffery A / Carvalho, Wanessa A / Cervelatti, Eliane P / Chacko, Elsa / Chapin, Jennifer E / Cheng, Ye / Choi, Jungwoo / Colley, Adam J / de Campos, Tatiana A / De Donato, Marcos / Santos, Isabel K F de Miranda / de Oliveira, Carlo J F / Deobald, Heather / Devinoy, Eve / Donohue, Kaitlin E / Dovc, Peter / Eberlein, Annett / Fitzsimmons, Carolyn J / Franzin, Alessandra M / Garcia, Gustavo R / Genini, Sem / Gladney, Cody J / Grant, Jason R / Greaser, Marion L / Green, Jonathan A / Hadsell, Darryl L / Hakimov, Hatam A / Halgren, Rob / Harrow, Jennifer L / Hart, Elizabeth A / Hastings, Nicola / Hernandez, Marta / Hu, Zhi-Liang / Ingham, Aaron / Iso-Touru, Terhi / Jamis, Catherine / Jensen, Kirsty / Kapetis, Dimos / Kerr, Tovah / Khalil, Sari S / Khatib, Hasan / Kolbehdari, Davood / Kumar, Charu G / Kumar, Dinesh / Leach, Richard / Lee, Justin C-M / Li, Changxi / Logan, Krystin M / Malinverni, Roberto / Marques, Elisa / Martin, William F / Martins, Natalia F / Maruyama, Sandra R / Mazza, Raffaele / McLean, Kim L / Medrano, Juan F / Moreno, Barbara T / Moré, Daniela D / Muntean, Carl T / Nandakumar, Hari P / Nogueira, Marcelo F G / Olsaker, Ingrid / Pant, Sameer D / Panzitta, Francesca / Pastor, Rosemeire C P / Poli, Mario A / Poslusny, Nathan / Rachagani, Satyanarayana / Ranganathan, Shoba / Razpet, Andrej / Riggs, Penny K / Rincon, Gonzalo / Rodriguez-Osorio, Nelida / Rodriguez-Zas, Sandra L / Romero, Natasha E / Rosenwald, Anne / Sando, Lillian / Schmutz, Sheila M / Shen, Libing / Sherman, Laura / Southey, Bruce R / Lutzow, Ylva Strandberg / Sweedler, Jonathan V / Tammen, Imke / Telugu, Bhanu Prakash V L / Urbanski, Jennifer M / Utsunomiya, Yuri T / Verschoor, Chris P / Waardenberg, Ashley J / Wang, Zhiquan / Ward, Robert / Weikard, Rosemarie / Welsh, Thomas H / White, Stephen N / Wilming, Laurens G / Wunderlich, Kris R / Yang, Jianqi / Zhao, Feng-Qi

Science (New York, N.Y.)

2009  Band 324, Heft 5926, Seite(n) 522–528

Abstract: To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which ... ...

Abstract To understand the biology and evolution of ruminants, the cattle genome was sequenced to about sevenfold coverage. The cattle genome contains a minimum of 22,000 genes, with a core set of 14,345 orthologs shared among seven mammalian species of which 1217 are absent or undetected in noneutherian (marsupial or monotreme) genomes. Cattle-specific evolutionary breakpoint regions in chromosomes have a higher density of segmental duplications, enrichment of repetitive elements, and species-specific variations in genes associated with lactation and immune responsiveness. Genes involved in metabolism are generally highly conserved, although five metabolic genes are deleted or extensively diverged from their human orthologs. The cattle genome sequence thus provides a resource for understanding mammalian evolution and accelerating livestock genetic improvement for milk and meat production.
Mesh-Begriff(e) Alternative Splicing ; Animals ; Animals, Domestic ; Biological Evolution ; Cattle ; Evolution, Molecular ; Female ; Genetic Variation ; Genome ; Humans ; Male ; MicroRNAs/genetics ; Molecular Sequence Data ; Proteins/genetics ; Sequence Analysis, DNA ; Species Specificity ; Synteny
Chemische Substanzen MicroRNAs ; Proteins
Sprache Englisch
Erscheinungsdatum 2009-04-26
Erscheinungsland United States
Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID 128410-1
ISSN 1095-9203 ; 0036-8075
ISSN (online) 1095-9203
ISSN 0036-8075
DOI 10.1126/science.1169588
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