Artikel ; Online: Serum BDNF Levels Among Patients with Alcohol Dependence, Depression and Alcohol Dependence with Comorbid Depression - A Comparative Study.
2023 Band 56, Heft 2, Seite(n) 225–233
Abstract: The study aimed to assess and compare the serum brain derived neurotrophic factor (BDNF) levels in patients with alcohol dependence, depression and alcohol dependence with comorbid depression. Three groups each of 30 alcohol-dependent, depressive and ... ...
Abstract | The study aimed to assess and compare the serum brain derived neurotrophic factor (BDNF) levels in patients with alcohol dependence, depression and alcohol dependence with comorbid depression. Three groups each of 30 alcohol-dependent, depressive and alcohol-dependent with comorbid depressive patients seeking treatment were included. BDNF levels were estimated, and scales were administered to assess severity of alcohol dependence (using severity of alcohol dependence questionnaire, SADQ) and depressive symptoms (using Hamilton depression rating scale, HDRS). The mean BDNF value in ADS, depression and ADS with comorbid depression group was 16.4 ng/mL, 14.4 ng/mL and 12.29 ng/mL respectively, and the differences were statistically significant. In ADS group and ADS with comorbid depression groups significant negative association existed between BDNF and SADQ scores ( |
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Mesh-Begriff(e) | Humans ; Brain-Derived Neurotrophic Factor/blood ; Alcoholism/epidemiology ; Alcoholism/blood ; Male ; Female ; Adult ; Middle Aged ; Comorbidity ; Depression/epidemiology ; Depression/blood ; Severity of Illness Index ; Psychiatric Status Rating Scales ; Depressive Disorder/epidemiology ; Depressive Disorder/blood | |||||
Chemische Substanzen | BDNF protein, human | |||||
Sprache | Englisch | |||||
Erscheinungsdatum | 2023-03-27 | |||||
Erscheinungsland | United States | |||||
Dokumenttyp | Journal Article ; Comparative Study | |||||
ZDB-ID | 392405-1 | |||||
ISSN | 2159-9777 ; 0279-1072 | |||||
ISSN (online) | 2159-9777 | |||||
ISSN | 0279-1072 | |||||
DOI | 10.1080/02791072.2023.2192985 | |||||
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Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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