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  1. Artikel ; Online: Hypohydration attenuates increases in creatinine clearance to oral protein loading and the renal hemodynamic response to exercise pressor reflex.

    Chapman, Christopher L / Holt, Sadie M / O'Connell, Cameron T / Brazelton, Shaun C / Medved, Hannah N / Howells, William A B / Reed, Emma L / Needham, Karen Wiedenfeld / Halliwill, John R / Minson, Christopher T

    Journal of applied physiology (Bethesda, Md. : 1985)

    2024  Band 136, Heft 3, Seite(n) 492–508

    Abstract: Insufficient hydration is prevalent among free living adults. This study investigated whether hypohydration ... ...

    Abstract Insufficient hydration is prevalent among free living adults. This study investigated whether hypohydration alters
    Mesh-Begriff(e) Female ; Male ; Young Adult ; Humans ; Creatinine ; Hand Strength ; Reflex ; Hemodynamics ; Water
    Chemische Substanzen Creatinine (AYI8EX34EU) ; Water (059QF0KO0R)
    Sprache Englisch
    Erscheinungsdatum 2024-01-11
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 219139-8
    ISSN 1522-1601 ; 0021-8987 ; 0161-7567 ; 8750-7587
    ISSN (online) 1522-1601
    ISSN 0021-8987 ; 0161-7567 ; 8750-7587
    DOI 10.1152/japplphysiol.00728.2023
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Acute kidney injury biomarkers and hydration assessments following prolonged mild hypohydration in healthy young adults.

    Chapman, Christopher L / Holt, Sadie M / O'Connell, Cameron T / Brazelton, Shaun C / Howells, William A B / Medved, Hannah N / Reed, Emma L / Needham, Karen Wiedenfeld / Halliwill, John R / Minson, Christopher T

    American journal of physiology. Renal physiology

    2023  Band 325, Heft 2, Seite(n) F199–F213

    Abstract: The high prevalence of inadequate hydration (e.g., hypohydration and underhydration) is concerning given that extreme heat increases excess hospitalizations for fluid/electrolyte disorders and acute kidney injury (AKI). Inadequate hydration may also be ... ...

    Abstract The high prevalence of inadequate hydration (e.g., hypohydration and underhydration) is concerning given that extreme heat increases excess hospitalizations for fluid/electrolyte disorders and acute kidney injury (AKI). Inadequate hydration may also be related to renal and cardiometabolic disease development. This study tested the hypothesis that prolonged mild hypohydration increases the urinary AKI biomarker product of insulin-like growth factor-binding protein 7 and tissue inhibitor of metalloproteinase-2 ([IGFBP7·TIMP-2]) compared with euhydration. In addition, we determined the diagnostic accuracy and optimal cutoffs of hydration assessments for discriminating positive AKI risk ([IGFBP·TIMP-2] >0.3 (ng/mL)
    Mesh-Begriff(e) Male ; Female ; Humans ; Young Adult ; Tissue Inhibitor of Metalloproteinase-2 ; Biomarkers ; Acute Kidney Injury/diagnosis ; Kidney ; Insulin-Like Growth Factor Binding Proteins ; Somatomedins
    Chemische Substanzen Tissue Inhibitor of Metalloproteinase-2 (127497-59-0) ; Biomarkers ; Insulin-Like Growth Factor Binding Proteins ; Somatomedins
    Sprache Englisch
    Erscheinungsdatum 2023-06-15
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 603837-2
    ISSN 1522-1466 ; 0363-6127
    ISSN (online) 1522-1466
    ISSN 0363-6127
    DOI 10.1152/ajprenal.00086.2023
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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