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  1. Buch ; Online ; E-Book: The neurology of HIV infection

    Brew, Bruce James

    (Handbook of clinical neurology ; 152)

    2018  

    Verfasserangabe volume editor Bruce James Brew
    Serientitel Handbook of clinical neurology ; 152
    Überordnung
    Schlagwörter HIV infections ; Neurology
    Thema/Rubrik (Code) 616.979207
    Sprache Englisch
    Umfang 1 Online-Ressource (xvi, 297 Seiten), Illustrationen
    Verlag Elsevier
    Erscheinungsort Amsterdam
    Erscheinungsland Niederlande
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019667685
    ISBN 978-0-444-63850-2 ; 9780444638496 ; 0-444-63850-4 ; 0444638490
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

    Kategorien

  2. Artikel ; Online: Plasma neurofilament light chain protein predicts greater brain-age gap, cognition, and cardiovascular risk in people with HIV.

    Vance, David E / Brew, Bruce James

    AIDS (London, England)

    2024  Band 38, Heft 7, Seite(n) 1081–1083

    Mesh-Begriff(e) Humans ; HIV Infections/complications ; Cardiovascular Diseases/blood ; Neurofilament Proteins/blood ; Male ; Middle Aged ; Female ; Adult ; Plasma/chemistry ; Cognition ; Brain ; Aged
    Chemische Substanzen neurofilament protein L ; Neurofilament Proteins
    Sprache Englisch
    Erscheinungsdatum 2024-05-01
    Erscheinungsland England
    Dokumenttyp Letter ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Journal Article
    ZDB-ID 639076-6
    ISSN 1473-5571 ; 0269-9370 ; 1350-2840
    ISSN (online) 1473-5571
    ISSN 0269-9370 ; 1350-2840
    DOI 10.1097/QAD.0000000000003880
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

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  3. Artikel ; Online: Is HIV Brain Disease Preventable?

    Brew, Bruce J

    Neurology(R) neuroimmunology & neuroinflammation

    2022  Band 9, Heft 2

    Mesh-Begriff(e) Brain Diseases ; HIV Infections/diagnosis ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; Humans
    Sprache Englisch
    Erscheinungsdatum 2022-02-09
    Erscheinungsland United States
    Dokumenttyp Editorial ; Comment
    ZDB-ID 2767740-0
    ISSN 2332-7812 ; 2332-7812
    ISSN (online) 2332-7812
    ISSN 2332-7812
    DOI 10.1212/NXI.0000000000001145
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Antiretroviral therapy intensification for HIV-associated neurocognitive disorder?

    Brew, Bruce J / Clifford, David B

    AIDS (London, England)

    2023  Band 37, Heft 13, Seite(n) 2095–2096

    Mesh-Begriff(e) Humans ; HIV Infections/complications ; HIV Infections/drug therapy ; AIDS Dementia Complex/drug therapy ; Anti-HIV Agents/therapeutic use ; Neurocognitive Disorders/drug therapy ; Antiretroviral Therapy, Highly Active ; Neuropsychological Tests
    Chemische Substanzen Anti-HIV Agents
    Sprache Englisch
    Erscheinungsdatum 2023-09-28
    Erscheinungsland England
    Dokumenttyp Journal Article ; Comment
    ZDB-ID 639076-6
    ISSN 1473-5571 ; 0269-9370 ; 1350-2840
    ISSN (online) 1473-5571
    ISSN 0269-9370 ; 1350-2840
    DOI 10.1097/QAD.0000000000003694
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Is neurocognitive ageing accelerated in virally suppressed people with HIV and multimorbidity?

    Cysique, Lucette A / Brew, Bruce J

    Brain : a journal of neurology

    2023  Band 146, Heft 3, Seite(n) 801–802

    Mesh-Begriff(e) Humans ; Multimorbidity ; Aging ; HIV Infections/complications ; Comorbidity
    Sprache Englisch
    Erscheinungsdatum 2023-01-21
    Erscheinungsland England
    Dokumenttyp Editorial ; Comment
    ZDB-ID 80072-7
    ISSN 1460-2156 ; 0006-8950
    ISSN (online) 1460-2156
    ISSN 0006-8950
    DOI 10.1093/brain/awad035
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Extracellular vesicle small noncoding RNAs: a window into pathogenesis and diagnosis.

    Hu, Guoku / Brew, Bruce J

    AIDS (London, England)

    2023  Band 37, Heft 5, Seite(n) 849–850

    Mesh-Begriff(e) Humans ; RNA, Small Untranslated/genetics ; HIV Infections ; MicroRNAs/genetics ; Extracellular Vesicles
    Chemische Substanzen RNA, Small Untranslated ; MicroRNAs
    Sprache Englisch
    Erscheinungsdatum 2023-03-02
    Erscheinungsland England
    Dokumenttyp Editorial ; Comment
    ZDB-ID 639076-6
    ISSN 1473-5571 ; 0269-9370 ; 1350-2840
    ISSN (online) 1473-5571
    ISSN 0269-9370 ; 1350-2840
    DOI 10.1097/QAD.0000000000003517
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

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  7. Buch: HIV neurology

    Brew, Bruce James

    (Contemporary neurology series ; 61)

    2001  

    Verfasserangabe Bruce James Brew
    Serientitel Contemporary neurology series ; 61
    Überordnung
    Schlagwörter HIV Infections / complications ; Aids-Related Oppurtunistic Infection ; Brain Diseases / etiology ; Muscular Diseases / etiology ; Neurologic Manifestations ; Peripheral Nervous System Diseases / etiology ; Spinal Cord Diseases / etiology
    Sprache Englisch
    Umfang XVI, 252 S. : Ill., graph. Darst.
    Verlag Oxford Univ. Press
    Erscheinungsort Oxford
    Erscheinungsland Vereinigte Staaten
    Dokumenttyp Buch
    HBZ-ID HT013126208
    ISBN 0-19-513363-3 ; 978-0-19-513363-9
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  8. Artikel ; Online: Reversible large-scale network disruption correlates with neurocognitive improvement in HIV-associated minor neurocognitive disorder with combined anti-retroviral therapy intensification: a prospective longitudinal resting-state functional magnetic resonance imaging study.

    Chaganti, Joga / Gates, Thomas M / Brew, Bruce J

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2023  Band 44, Heft 9, Seite(n) 3261–3269

    Abstract: Objective: HIV-associated neurocognitive disorder (HAND) affects multiple cognitive domains and currently, the neuropsychological testing is the gold standard to identify these deficits. The aim of this longitudinal 12-month pilot study is to determine ... ...

    Abstract Objective: HIV-associated neurocognitive disorder (HAND) affects multiple cognitive domains and currently, the neuropsychological testing is the gold standard to identify these deficits. The aim of this longitudinal 12-month pilot study is to determine the effect of intensified combination antiretroviral therapy (cART) on rs-fMRI in virally suppressed (both in CSF and blood) patients with active HAND (those who have progressive neurocognitive impairment) and correlated with neurocognitive function tests.
    Methods: In this pilot study, we have evaluated sixteen patients with active HAND with viral suppression in both blood and CSF to study the effect of cART on functional connectivity. Participants underwent rs-fMRI at the baseline (time point-1 (TP-1) and 12-month visits (time point-2 (TP-2)). Connectivity in the five major networks was measured at TP-1 and TP-2 using the seed-based approach. All the participants underwent a five-domain neuropsychological battery at TP-1 and TP-2. Neurocognitive scores (NC) as well as blood and CSF markers were correlated with functional connectivity (FC).
    Results: There was a significant increase in the FC between the two time points within the executive, salience, default mode, dorsal attention, and visual networks at voxel level threshold of p < 0.001 and cluster level threshold of p < 0.05 and corrected for false detection rate (FDR). The neurocognitive scores were positively correlated with all the networks at similar cluster and voxel level thresholds.
    Conclusions: These results indicate that rs-fMRI can be potentially used as one of the biomarkers for treatment efficacy in HAND.
    Mesh-Begriff(e) Humans ; HIV ; Prospective Studies ; Pilot Projects ; HIV Infections/complications ; HIV Infections/diagnostic imaging ; HIV Infections/drug therapy ; Neurocognitive Disorders/complications ; Neurocognitive Disorders/pathology ; Magnetic Resonance Imaging ; Brain ; Brain Mapping
    Sprache Englisch
    Erscheinungsdatum 2023-04-13
    Erscheinungsland Italy
    Dokumenttyp Journal Article
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-023-06783-z
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: Preface.

    Brew, Bruce J

    Handbook of clinical neurology

    2018  Band 152, Seite(n) xi

    Mesh-Begriff(e) Guidelines as Topic ; HIV/pathogenicity ; Humans ; Knowledge
    Sprache Englisch
    Erscheinungsdatum 2018-03-06
    Erscheinungsland Netherlands
    Dokumenttyp Editorial
    ISSN 0072-9752
    ISSN 0072-9752
    DOI 10.1016/B978-0-444-63849-6.09988-6
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Introduction to HIV infection and HIV neurology.

    Brew, Bruce James

    Handbook of clinical neurology

    2018  Band 152, Seite(n) 1–2

    Abstract: In this introductory chapter the impact of combination antiretriviral therapy is discussed. Three different "types" of HIV infection are described according to medication adherence and efficacy. Next, general principles of HIV related neurologic ... ...

    Abstract In this introductory chapter the impact of combination antiretriviral therapy is discussed. Three different "types" of HIV infection are described according to medication adherence and efficacy. Next, general principles of HIV related neurologic complications are defined. Last, a clinical approach to the HIV infected patient with a neurologic complication is then detailed.
    Mesh-Begriff(e) Antiretroviral Therapy, Highly Active/methods ; Antiretroviral Therapy, Highly Active/trends ; HIV Infections/diagnosis ; HIV Infections/epidemiology ; HIV Infections/therapy ; Humans ; Nervous System Diseases/diagnosis ; Nervous System Diseases/epidemiology ; Nervous System Diseases/therapy
    Sprache Englisch
    Erscheinungsdatum 2018-05-07
    Erscheinungsland Netherlands
    Dokumenttyp Introductory Journal Article
    ISSN 0072-9752
    ISSN 0072-9752
    DOI 10.1016/B978-0-444-63849-6.00001-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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