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  1. Artikel ; Online: Protocol for Evaluating Remote Patient Blood Pressure Monitoring Adapted to Black Women and Birthing Persons.

    Patchen, Loral / McCullers, Asli / Budd, Serenity G / Blumenthal, H Joseph / Evans, W Douglas

    International journal of environmental research and public health

    2024  Band 21, Heft 5

    Abstract: Cardiovascular disease is the leading cause of maternal death among Black women in the United States. A large, urban hospital adopted remote patient blood pressure monitoring (RBPM) to increase blood pressure monitoring and improve the management of ... ...

    Abstract Cardiovascular disease is the leading cause of maternal death among Black women in the United States. A large, urban hospital adopted remote patient blood pressure monitoring (RBPM) to increase blood pressure monitoring and improve the management of hypertensive disorders of pregnancy (HDP) by reducing the time to diagnosis of HDP. The digital platform integrates with the electronic health record (EHR), automatically inputting RBPM readings to the patients' chart; communicating elevated blood pressure values to the healthcare team; and offers a partial offset of the cost through insurance plans. It also allows for customization of the blood pressure values that prompt follow-up to the patient's risk category. This paper describes a protocol for evaluating its impact. Objective 1 is to measure the effect of the digitally supported RBPM on the time to diagnosis of HDP. Objective 2 is to test the effect of cultural tailoring to Black participants. The ability to tailor digital content provides the opportunity to test the added value of promoting social identification with the intervention, which may help achieve equity in severe maternal morbidity events related to HDP. Evaluation of this intervention will contribute to the growing literature on digital health interventions to improve maternity care in the United States.
    Mesh-Begriff(e) Humans ; Female ; Pregnancy ; Black or African American ; Hypertension, Pregnancy-Induced/diagnosis ; Blood Pressure Determination/methods ; Adult ; Telemedicine
    Sprache Englisch
    Erscheinungsdatum 2024-05-08
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph21050603
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Interactive effects of protonated nicotine concentration and device power on ENDS nicotine delivery, puff topography, and subjective effects.

    Eversole, Alisha / Budd, Serenity / Karaoghlanian, Nareg / Lipato, Thokozeni / Eissenberg, Thomas / Breland, Alison B

    Experimental and clinical psychopharmacology

    2022  Band 31, Heft 2, Seite(n) 443–454

    Abstract: Electronic nicotine delivery systems (ENDSs) produce an aerosol by heating a liquid that often contains nicotine. The nicotine can be protonated that may make the aerosol easier to inhale than freebase nicotine. This study's purpose is to determine, in ... ...

    Abstract Electronic nicotine delivery systems (ENDSs) produce an aerosol by heating a liquid that often contains nicotine. The nicotine can be protonated that may make the aerosol easier to inhale than freebase nicotine. This study's purpose is to determine, in cigarette smokers and ENDS users, the effects of three concentrations of protonated nicotine aerosolized at two different power settings. Forty-five participants (22 cigarette smokers and 23 ENDS users) completed some or all of six sessions that varied by liquid nicotine concentration (10, 15, or 30 mg/ml protonated nicotine) and device power (15 or 30 W). Participants took 10 puffs from each product and then used each product for 90 min
    Mesh-Begriff(e) Humans ; Nicotine ; Smoking ; Smokers ; Electronic Nicotine Delivery Systems ; Tobacco Products
    Chemische Substanzen Nicotine (6M3C89ZY6R)
    Sprache Englisch
    Erscheinungsdatum 2022-06-13
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1209960-0
    ISSN 1936-2293 ; 1064-1297
    ISSN (online) 1936-2293
    ISSN 1064-1297
    DOI 10.1037/pha0000576
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: The baseline risk of multiple febrile seizures in the same febrile illness: a meta-analysis.

    Henry, Christopher / Cockburn, Chelsea / Simpson, Mary Helen / Budd, Serenity / Wang, Chen / Dinov, Darina

    European journal of pediatrics

    2022  Band 181, Heft 6, Seite(n) 2201–2213

    Abstract: The baseline risk for multiple febrile seizures within the same febrile illness is largely unknown. Estimates range from 5 to 30%. Imprecise estimates can lead to incorrectly powering studies investigating the management of febrile seizures. To estimate ... ...

    Abstract The baseline risk for multiple febrile seizures within the same febrile illness is largely unknown. Estimates range from 5 to 30%. Imprecise estimates can lead to incorrectly powering studies investigating the management of febrile seizures. To estimate the risk of multiple febrile seizures in the same febrile illness, we systematically reviewed and conducted a meta-analysis of studies from January 2000 to December 2021 that contained data for the number of children for both simple and complex febrile seizures in the same febrile illness. We searched MEDLINE, EMBASE, and Web of Science for randomized, quasi-randomized, prospective, and retrospective trials that involved children with febrile seizures. A total of 23,131 febrile illnesses with febrile seizures met the inclusion criteria. The estimated baseline risk of multiple febrile seizures in the same febrile illness was 17% (95% CI, 16-19%). However, the 30 cohorts that included both admitted and non-admitted patients had a lower percentage of multiple FSs within the same illness (14%; 95% CI, 12-15%) than the 30 cohorts that enrolled only admitted patients (20%; 95% CI, 16-25%).
    Conclusion: Researchers can use estimates in this paper to design future studies. Taking into the account the substantial heterogeneity between countries and studies, clinicians could cautiously use our estimates in their clinical assessment and be better able to set parental expectations about a child's chances of having another febrile seizure during the current illness.
    Trial registration: PROSPERO CRD42020191784. Registered July 18, 2020.
    What is known: • There is renewed interest in the diagnostic workup and prophylactic treatment of febrile seizures to prevent repeat seizures in the same febrile illness. • There is a lack of accurate estimates of the baseline risk for multiple febrile seizures in the same illness to properly design studies investigating management.
    What is new: • This study provides the most robust estimates for the baseline risk for multiple febrile seizures in the same illness.
    Mesh-Begriff(e) Child ; Hospitalization ; Humans ; Prospective Studies ; Retrospective Studies ; Seizures, Febrile/diagnosis ; Seizures, Febrile/epidemiology ; Seizures, Febrile/etiology
    Sprache Englisch
    Erscheinungsdatum 2022-03-16
    Erscheinungsland Germany
    Dokumenttyp Journal Article ; Meta-Analysis
    ZDB-ID 194196-3
    ISSN 1432-1076 ; 0340-6199 ; 0943-9676
    ISSN (online) 1432-1076
    ISSN 0340-6199 ; 0943-9676
    DOI 10.1007/s00431-022-04431-w
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Quality of life and safety impact of COVID-19 associated smell and taste disturbances.

    Coelho, Daniel H / Reiter, Evan R / Budd, Serenity G / Shin, Yongyun / Kons, Zachary A / Costanzo, Richard M

    American journal of otolaryngology

    2021  Band 42, Heft 4, Seite(n) 103001

    Abstract: Objective: The association between COVID-19 and chemosensory loss has garnered substantial attention, however to date little is known about the real-life consequences of impairment in this unique patient population. The aim of this study is to evaluate ... ...

    Abstract Objective: The association between COVID-19 and chemosensory loss has garnered substantial attention, however to date little is known about the real-life consequences of impairment in this unique patient population. The aim of this study is to evaluate the quality of life (QOL) and personal safety deficits experienced by patients with COVID-19 infection.
    Study design: Prospective, longitudinal questionnaires.
    Setting: National survey.
    Methods: A longitudinal web-based nationwide survey of adults with COVID-19 and/or a sudden change in smell and taste was launched April 10, 2020. Previously published questions on chemosensory-related QOL and safety events were asked at the 6-month follow-up survey.
    Results: As of February 10, 2021, 480 eligible respondents took the 6-month questionnaire, of whom 322 were COVID-19 positive. Impact on QOL was substantial with 96% of subjects reporting at least one of the defined deficits, and over 75% reporting at least 3 of these. "Reduced enjoyment of food" was the most common complaint (87%), while 43% of subjects self-reported depression. The prevalence of safety-related issues was common in this population, with over 57% reporting at least one, and 36% reporting 2 or more events. Of the events asked, the inability to smell smoke that others could perceive was the most common at 45%.
    Conclusions: COVID-19 associated chemosensory losses have a real and substantial impact on both quality of life and safety, beyond mere inconvenience. The high prevalence of these issues despite a relatively short period of olfactory deficit should alert clinicians to the serious risks to an already vulnerable patient population.
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; COVID-19/complications ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Olfaction Disorders/complications ; Olfaction Disorders/psychology ; Olfaction Disorders/virology ; Prospective Studies ; Quality of Life ; Risk ; Surveys and Questionnaires ; Taste Disorders/complications ; Taste Disorders/psychology ; Taste Disorders/virology ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2021-03-22
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2021.103001
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Predictors of smell recovery in a nationwide prospective cohort of patients with COVID-19.

    Coelho, Daniel H / Reiter, Evan R / Budd, Serenity G / Shin, Yongyun / Kons, Zachary A / Costanzo, Richard M

    American journal of otolaryngology

    2021  Band 43, Heft 1, Seite(n) 103239

    Abstract: Objective: To determine which factors (demographic, symptoms, comorbidities, and treatments) are associated with recovery of smell in patients with COVID-19 associated olfactory loss.: Study design: Prospective, longitudinal questionnaires.: ... ...

    Abstract Objective: To determine which factors (demographic, symptoms, comorbidities, and treatments) are associated with recovery of smell in patients with COVID-19 associated olfactory loss.
    Study design: Prospective, longitudinal questionnaires.
    Setting: National survey.
    Methods: A longitudinal web-based nationwide survey of adults with COVID-19 associated smell and taste loss was launched April 10, 2020. After completing an initial entry survey, participants received detailed follow-up questionnaires 14 days, and 1, 3 and 6 months later.
    Results: As of June 25, 2021, 798 participants met study inclusion criteria and completed 6-month questionnaires. Of demographic characteristics only age <40 years was positively associated with smell recovery (p < .003). Of symptoms, difficulty breathing was negatively associated with smell recovery (p < .004), and nasal congestion positively associated with smell recovery (p < .03). Of pre-existing comorbidities only previous head injury (p < .017) was negatively associated with smell recovery. None of the queried medications used to treat COVID were associated with better rates of smell recovery.
    Conclusions: Age <40 and presence of nasal congestion at time of COVID-19 infection were predictive of improved rates of smell recovery, while difficulty breathing at time of COVID-19 infection, and prior head trauma predicted worsened rates of recovery. Further study will be required to identify potential mechanisms for the other observed associations. Such information can be used by clinicians to counsel patients suffering COVID-19 associated smell loss as to prognosis for recovery.
    Mesh-Begriff(e) Adult ; COVID-19/complications ; Female ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Olfaction Disorders/physiopathology ; Olfaction Disorders/virology ; Predictive Value of Tests ; Prospective Studies ; Recovery of Function ; SARS-CoV-2 ; Surveys and Questionnaires
    Sprache Englisch
    Erscheinungsdatum 2021-09-16
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2021.103239
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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