Artikel: The effect of omalizumab treatment on severe allergic asthma and allergic comorbidities: real-life experience from the Czech Anti-IgE Registry.
Postepy dermatologii i alergologii
2018 Band 35, Heft 5, Seite(n) 510–515
Abstract: Introduction: Omalizumab is indicated for the treatment of severe allergic asthma (SAA) and chronic spontaneous urticaria, although a number of studies have confirmed the effectiveness of this therapy also for other IgE-mediated diseases.: Aim: To ... ...
Abstract | Introduction: Omalizumab is indicated for the treatment of severe allergic asthma (SAA) and chronic spontaneous urticaria, although a number of studies have confirmed the effectiveness of this therapy also for other IgE-mediated diseases. Aim: To assess the impact of anti-IgE therapy on SAA and comorbid IgE-mediated allergic diseases in patients treated with omalizumab for SAA enrolled in the CAR (Czech Anti-IgE Registry). Material and methods: Three hundred and ten patients with SAA treated with omalizumab were enrolled in the CAR. Two hundred and twenty-nine individuals were evaluated after 12 months of omalizumab treatment for asthma control test (ACT), examination of fractional exhaled nitric oxide (FENO), forced expiratory volume in 1 s (FEV Results: After 12 months of treatment with omalizumab, patients experienced a significant improvement of ACT and FEV Conclusions: In the CAR registry, patients with SAA treated with omalizumab showed a significant positive effect of anti-IgE therapy not only on the asthma control, but also on allergic comorbidities. |
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Sprache | Englisch |
Erscheinungsdatum | 2018-07-19 |
Erscheinungsland | Poland |
Dokumenttyp | Journal Article |
ZDB-ID | 2596142-1 |
ISSN | 1642-395X |
ISSN | 1642-395X |
DOI | 10.5114/ada.2018.77243 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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