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Artikel ; Online: From gut to brain: understanding the role of microbiota in inflammatory bowel disease.

Wang, Siyu / Zhou, Shuwei / Han, Zhongyu / Yu, Bin / Xu, Yin / Lin, Yumeng / Chen, Yutong / Jin, Zi / Li, Yalong / Cao, Qinhan / Xu, Yunying / Zhang, Qiang / Wang, Yuan-Cheng

Frontiers in immunology

2024  Band 15, Seite(n) 1384270

Abstract: With the proposal of the "biological-psychological-social" model, clinical decision-makers and researchers have paid more attention to the bidirectional interactive effects between psychological factors and diseases. The brain-gut-microbiota axis, as an ... ...

Abstract With the proposal of the "biological-psychological-social" model, clinical decision-makers and researchers have paid more attention to the bidirectional interactive effects between psychological factors and diseases. The brain-gut-microbiota axis, as an important pathway for communication between the brain and the gut, plays an important role in the occurrence and development of inflammatory bowel disease. This article reviews the mechanism by which psychological disorders mediate inflammatory bowel disease by affecting the brain-gut-microbiota axis. Research progress on inflammatory bowel disease causing "comorbidities of mind and body" through the microbiota-gut-brain axis is also described. In addition, to meet the needs of individualized treatment, this article describes some nontraditional and easily overlooked treatment strategies that have led to new ideas for "psychosomatic treatment".
Mesh-Begriff(e) Humans ; Gastrointestinal Microbiome ; Brain/metabolism ; Inflammatory Bowel Diseases/etiology ; Inflammatory Bowel Diseases/therapy ; Inflammatory Bowel Diseases/metabolism ; Microbiota ; Mental Disorders/metabolism
Sprache Englisch
Erscheinungsdatum 2024-03-21
Erscheinungsland Switzerland
Dokumenttyp Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID 2606827-8
ISSN 1664-3224 ; 1664-3224
ISSN (online) 1664-3224
ISSN 1664-3224
DOI 10.3389/fimmu.2024.1384270
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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