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  1. Artikel: Editorial: Application of data mining in pharmaceutical research.

    Bu, Qingting / Lyu, Jun / Zhao, Limei / Cao, Shiyi / Jia, Deyong / Pan, Zhenyu

    Frontiers in pharmacology

    2024  Band 15, Seite(n) 1388738

    Sprache Englisch
    Erscheinungsdatum 2024-03-01
    Erscheinungsland Switzerland
    Dokumenttyp Editorial
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1388738
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Association of changes in plant-based diet consumption with all-cause mortality among older adults in China: a prospective study from 2008 to 2019.

    Huang, Shen / Lou, Yiling / Wang, Shiqi / You, Qiqi / Jiang, Qingqing / Cao, Shiyi

    The journal of nutrition, health & aging

    2024  Band 28, Heft 2, Seite(n) 100027

    Abstract: Objectives: To examine the association of changes in plant-based diet consumption with all-cause mortality among older adults in China.: Design: Cohort study.: Setting: This cohort study of 11 years used data from the Chinese Longitudinal Healthy ... ...

    Abstract Objectives: To examine the association of changes in plant-based diet consumption with all-cause mortality among older adults in China.
    Design: Cohort study.
    Setting: This cohort study of 11 years used data from the Chinese Longitudinal Healthy Longevity Survey (CLHLS), a long-term, nationwide survey covering 23 provinces in China.
    Participants: A total of 7843 older participants aged ≥60 years were included in this study.
    Measurements: Changes in plant-based diets consumption (2008-2011) were assessed by 3 graded plant-based diet indices, including an overall plant-based diet index (PDI), a healthful plant-based diet index (hPDI), and an unhealthful plant-based diet index (uPDI). The main outcome was all-cause mortality. Multivariable-adjusted Cox proportional-hazards models were fitted to estimate hazard ratios (HRs) and 95% confidence intervals (95% CIs) of mortality for changes in PDI, hPDI, and uPDI.
    Results: A total of 7843 participants (mean [SD] age, 82.2 [10.9] years; 3588 [45.7%] men) were included in this study. During a median (IQR) of 9 (5-10) years of follow-up, 3749 deaths were documented. Compared with older adults whose plant-based diet indices were relatively stable, older adults with the greatest decrease (quintile 1) in PDI, hPDI, and uPDI had respectively 32% (95% CI, 19%-47%) higher, 21% (95% CI, 9%-33%) higher, and 10% (95% CI, 4%-21%) lower risk of death. Compared with older adults whose diet indices were relatively stable, older adults with the greatest increase (quintile 5) in uPDI had a 13% higher risk of death (95% CI, 1%-21%), while no significant associations of the increased PDI and hPDI with all-cause mortality were observed.
    Conclusion: Maintaining the consumption of overall and healthful plant-based diets, and decreasing the consumption of an unhealthful plant-based diet can be beneficial in preventing or delaying premature death among Chinese older adults.
    Mesh-Begriff(e) Male ; Humans ; Aged ; Aged, 80 and over ; Female ; Prospective Studies ; Cohort Studies ; Diet, Plant-Based ; China/epidemiology ; Diet, Healthy ; Diet
    Sprache Englisch
    Erscheinungsdatum 2024-01-01
    Erscheinungsland France
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2081921-3
    ISSN 1760-4788 ; 1279-7707
    ISSN (online) 1760-4788
    ISSN 1279-7707
    DOI 10.1016/j.jnha.2023.100027
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Association of social isolation and loneliness with the risk of hypertension in middle aged and older adults: Findings from a national representative longitudinal survey.

    Wang, Shiqi / Zhang, Hao / Lou, Yiling / You, Qiqi / Jiang, Qingqing / Cao, Shiyi

    Journal of affective disorders

    2024  Band 349, Seite(n) 577–582

    Abstract: Background: Social isolation and loneliness have been proved to be associated with many adverse health outcomes, but their influence on hypertension remains unclear. This study aimed to assess the relationship of social isolation and loneliness with ... ...

    Abstract Background: Social isolation and loneliness have been proved to be associated with many adverse health outcomes, but their influence on hypertension remains unclear. This study aimed to assess the relationship of social isolation and loneliness with hypertension risk among middle-aged and older adults in China.
    Methods: We used data from the 2011 and 2015 waves of the China Health and Retirement Longitudinal Study. Participants were assessed for social isolation and loneliness at baseline, and hypertension was identified by self-report and blood pressure measurement at follow-up in 2015. Binary logistic regression analyses were conducted to assess the association of social isolation and loneliness with the risk of hypertension.
    Results: A total of 3711 residents were included. 13.7 % of the participants had high level of social isolation and 18.1 % felt lonely. During the four-year follow up period, 651 participants developed hypertension. People with high level of social isolation had an increased risk of hypertension (odds ratio [OR]: 1.40, 95 % confidence interval [CI]: 1.09-1.79). Similar results were found between social isolation score and hypertension risk (OR: 1.14, 95 % CI: 1.04-1.26). No significant association between loneliness and hypertension or any interaction effect of social isolation and loneliness on hypertension were observed.
    Limitations: Limited by the structure of questionnaire, some of the information was derived by self-report, which may lead to recalling bias.
    Conclusion: Social isolation, rather than loneliness was associated with hypertension for middle aged and older adults. Social support needs to be strengthened for hypertension prevention in community.
    Mesh-Begriff(e) Humans ; Middle Aged ; Aged ; Loneliness ; Longitudinal Studies ; Social Isolation ; Social Support ; Hypertension/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2024-01-08
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2024.01.008
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Response to Letter by Dr. Ajay Malhotra.

    Yu, Xinyu / Cao, Shiyi

    Journal of stroke

    2020  Band 22, Heft 3, Seite(n) 421

    Sprache Englisch
    Erscheinungsdatum 2020-09-29
    Erscheinungsland Korea (South)
    Dokumenttyp Journal Article ; Comment
    ZDB-ID 2814366-8
    ISSN 2287-6405 ; 2287-6391
    ISSN (online) 2287-6405
    ISSN 2287-6391
    DOI 10.5853/jos.2020.02859
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Chitosan/silk fibroin composite bilayer PCL nanofibrous mats for bone regeneration with enhanced antibacterial properties and improved osteogenic potential

    Wang, Xiaoxuan / Peng, Yan / Wu, Yang / Cao, Shiyi / Deng, Hongbing / Cao, Zhengguo

    International Journal of Biological Macromolecules. 2023 Mar., v. 230 p.123265-

    2023  

    Abstract: In regenerative medicine and bone tissue engineering, various composite materials are enormously popular, but the final tissue restoration outcome is not always satisfactory. In this study, bilayer-deposited multifunctional nanofiber mats were ... ...

    Abstract In regenerative medicine and bone tissue engineering, various composite materials are enormously popular, but the final tissue restoration outcome is not always satisfactory. In this study, bilayer-deposited multifunctional nanofiber mats were successfully fabricated with an osteogenic side of silk fibroin/poly (ε-caprolactone) (referred to as SF/PCL) and an antibacterial side of poly (ε-caprolactone)/chitosan (referred to as PCL/CS). The PCL/CS-SF/PCL (referred to as PCSP) mats exhibited biocompatible properties, sufficient hydrophilicity and mechanical properties, as well as a higher breaking strength (3.6 MPa) than the monolayer of SF/PCL mats (1.5 MPa). The antibacterial side of PCSP mats (A-layer) demonstrated ideal antibacterial potency because the survival rate of Escherichia coli (E. coli) (approximately 25 %) and Staphylococcus aureus (S. aureus) (approximately 15 %) were both significantly lower. Subsequently, the plasmid encoding runt related transcription factor 2 (Runx2) was complexed with the osteogenic side of PCSP mats (O-layer) through polyethyleneimine (PEI), thereby enhancing both osteogenesis-related gene expression and the formation of mineralized nodules. Similarly, the implantation of PCSP+Runx2 mats effectively promoted bone tissue generation in vivo. These results indicated the excellent prospects of applying PCSP mats to bone regeneration with gene delivery.
    Schlagwörter Escherichia coli ; Staphylococcus aureus ; bone formation ; bones ; chitosan ; fibroins ; gene expression ; gene transfer ; hydrophilicity ; medicine ; mineralization ; nanofibers ; plasmids ; polyethyleneimine ; survival rate ; transcription factors ; Double-layer ; Multifunctional ; Bone tissue engineering
    Sprache Englisch
    Erscheinungsverlauf 2023-03
    Erscheinungsort Elsevier B.V.
    Dokumenttyp Artikel ; Online
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.123265
    Datenquelle NAL Katalog (AGRICOLA)

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  6. Artikel: Dynamic prediction of urban landscape pattern based on remote sensing image fusion

    Cao, Shi-yi / Hu, Xi-jun

    International journal of environmental technology and management

    2021  Band 24, Heft 1/2, Seite(n) 18

    Sprache Englisch
    Dokumenttyp Artikel
    ZDB-ID 2080011-3
    ISSN 1466-2132
    Datenquelle Current Contents Ernährung, Umwelt, Agrar

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    Z 7461: Hefte anzeigen

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  7. Artikel: Adherence to the Chinese Food Pagoda in the High-Risk Population of Non-communicable Diseases Aged 35-59 in Central China.

    Jiang, Qingqing / You, Qiqi / Lou, Yiling / Wang, Shiqi / Cao, Shiyi

    Frontiers in nutrition

    2022  Band 9, Seite(n) 781963

    Abstract: Objectives: A healthy dietary habit is essential for preventing non-communicable diseases (NCDs). We aimed to assess the adherence to the Chinese Food Pagoda (CFP) proposed in the Chinese Dietary Guidelines 2016 in the high-risk population of NCDs in ... ...

    Abstract Objectives: A healthy dietary habit is essential for preventing non-communicable diseases (NCDs). We aimed to assess the adherence to the Chinese Food Pagoda (CFP) proposed in the Chinese Dietary Guidelines 2016 in the high-risk population of NCDs in central China.
    Methods: A cross-sectional study was conducted in two large enterprises (totally 3,016 employees) from October to December 2019 in Hubei Province (central China). The high-risk population of NCDs was identified by physical examination, laboratory test and face-to-face questionnaire survey according to the
    Results: A total of 821 participants aged 35-59 years old with at least one high-risk factor of NCDs were enrolled in our study. Of them, 53.8% were daily smokers, 49.6% had elevated blood cholesterol, 31.4% were centrally obese, 23.3% had high normal blood pressure, and 3.5% had impaired fasting glucose. Significant disparity was detected in the high-risk population of NCDs between real food consumption and the CFP's recommendation (
    Conclusion: Adherence to CFP in the high-risk population of NCDs appeared to be challenging. It is necessary to adopt dietary education campaign focusing on the high-risk population of NCDs to prevent or delay the occurrence of NCDs.
    Sprache Englisch
    Erscheinungsdatum 2022-03-04
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.781963
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Meta-analysis of the association between periodontal disease, periodontal treatment and carotid intima-media thickness.

    Ding, Lifang / You, Qiqi / Jiang, Qingqing / Cao, Shiyi / Jiang, Shengjun

    Journal of periodontal research

    2022  Band 57, Heft 4, Seite(n) 690–697

    Abstract: Periodontal disease is a major threat to oral health and would further contribute to systemic diseases without timely control. We aimed to evaluate the relation between periodontal disease, periodontal treatment and carotid intima-media thickness (CIMT) ... ...

    Abstract Periodontal disease is a major threat to oral health and would further contribute to systemic diseases without timely control. We aimed to evaluate the relation between periodontal disease, periodontal treatment and carotid intima-media thickness (CIMT) based on available epidemiological and clinical evidence. PubMed and Scopus were searched for relevant studies through May 2021. Observational studies reporting risk estimates with 95% confidence intervals (95% CIs) for the association between periodontal disease (including periodontitis and gingivitis) and risk of increased CIMT (defined as CIMT value that exceeded the cut-off value of clinical and prognostic significance), as well as interventional studies providing mean values with standard deviations of CIMT before and after periodontal intervention, were included. Random-effect models for meta-analysis were used to calculate the summary effect estimates with 95% CIs. A total of 406 citations were retrieved from electronic databases and 45 full-text articles were screened, leaving 11 articles using ultrasound to measure CIMT with 8744 participants included. Pooled results of seven cross-sectional studies involving 8558 participants indicated that compared to those without periodontitis, patients with periodontitis and those with severe periodontitis had an odds ratio of 1.42 (95% CI: 1.16, 1.75) and 1.70 (95% CI: 1.24, 2.33) for increased CIMT, respectively. Although publication bias was detected in these results, odds ratios corrected by the trim-and-fill method were still statistically significant. Results of four non-randomized controlled trials with 186 patients suggested that periodontal intervention may help reduce CIMT in patients with periodontal disease in the short term. Periodontitis, especially severe periodontitis, was significantly associated with the risk of increased CIMT. Periodontal intervention might help slow the progression of carotid intima-media thickening in patients with periodontal disease in the short term.
    Mesh-Begriff(e) Carotid Intima-Media Thickness ; Cross-Sectional Studies ; Humans ; Periodontal Diseases/complications ; Periodontal Diseases/diagnostic imaging ; Periodontal Diseases/therapy ; Periodontitis/complications ; Risk Factors
    Sprache Englisch
    Erscheinungsdatum 2022-06-14
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Meta-Analysis ; Review
    ZDB-ID 390953-0
    ISSN 1600-0765 ; 0022-3484
    ISSN (online) 1600-0765
    ISSN 0022-3484
    DOI 10.1111/jre.13006
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Long-term air pollution exposure associates with increased risk of coronary heart disease morbidity and mortality.

    Huang, Lu / Fu, Wenning / Xia, Liangtao / Cao, Shiyi

    European journal of preventive cardiology

    2021  Band 28, Heft 18, Seite(n) e6–e10

    Mesh-Begriff(e) Air Pollutants/toxicity ; Air Pollution/statistics & numerical data ; Coronary Disease/diagnosis ; Coronary Disease/epidemiology ; Environmental Exposure/statistics & numerical data ; Humans ; Morbidity ; Particulate Matter/toxicity
    Chemische Substanzen Air Pollutants ; Particulate Matter
    Sprache Englisch
    Erscheinungsdatum 2021-02-23
    Erscheinungsland England
    Dokumenttyp Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2626011-6
    ISSN 2047-4881 ; 2047-4873
    ISSN (online) 2047-4881
    ISSN 2047-4873
    DOI 10.1093/eurjpc/zwaa012
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: Letter to the editor regarding a meta-analysis of JAK inhibitors and psoriatic arthritis.

    Zuo, Yuyue / Dai, Lei / Cao, Shiyi

    Autoimmunity reviews

    2021  Band 21, Heft 1, Seite(n) 102926

    Mesh-Begriff(e) Arthritis, Psoriatic/drug therapy ; Arthritis, Rheumatoid ; Humans ; Janus Kinase Inhibitors/adverse effects
    Chemische Substanzen Janus Kinase Inhibitors
    Sprache Englisch
    Erscheinungsdatum 2021-08-26
    Erscheinungsland Netherlands
    Dokumenttyp Letter ; Comment
    ZDB-ID 2144145-5
    ISSN 1873-0183 ; 1568-9972
    ISSN (online) 1873-0183
    ISSN 1568-9972
    DOI 10.1016/j.autrev.2021.102926
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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