Artikel ; Online: Impact of Routine Gastric Aspirate Monitoring on Very Low Birth Weight Early Preterm Infants.
Journal of pediatric gastroenterology and nutrition
2023 Band 76, Heft 4, Seite(n) 517–522
Abstract: Objectives: Routine gastric aspirate (RGA) monitoring is a common yet controversial practice intended for early identification of gastrointestinal pathology in infants receiving gavage feeds. Our objectives were to evaluate the association of ceasing ... ...
| Abstract | Objectives: Routine gastric aspirate (RGA) monitoring is a common yet controversial practice intended for early identification of gastrointestinal pathology in infants receiving gavage feeds. Our objectives were to evaluate the association of ceasing RGA monitoring on the incidence of necrotizing enterocolitis (NEC) as well as nutritional outcomes in a large population of very low birth weight (VLBW) and very preterm neonates. Methods: Retrospective record review of neonates born ≤32 weeks and/or VLBW from 2 cohorts: (1) during pre-feed RGA monitoring (September 2015 to June 2018) and (2) after cessation of RGA ("non-RGA") monitoring (July 2018 to December 2020). We compared incidence of NEC, time-to-full enteral feeds, central line duration, and duration of parenteral nutrition (PN) in bivariate and multivariable models accounting for changes in feeding protocols over time. Results: We identified 617 subjects, 53% in the RGA monitoring cohort (n = 327) and 47% in non-RGA cohort (n = 290). The non-RGA cohort had feeds initiated earlier ( P < 0.0001), achieved full enteral feeds more rapidly ( P < 0.0001), received a shorter duration of PN ( P = 0.0003), and had shorter central access duration ( P < 0.0001) without increasing NEC risk. In fact, the non-RGA cohort had a lower incidence of NEC ( P = 0.0345) compared to the RGA cohort. Even after adjusting for changes in feeding protocols over time in a multivariable model, the RGA cohort had significantly higher odds of NEC. Conclusions: Pre-feed RGA monitoring in the absence of concerning clinical exam findings is not indicated for neonates receiving gavage feeds as it does not improve NEC incidence but instead may delay important nutritional outcomes such as feed initiation and central line removal. |
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| Mesh-Begriff(e) | Infant, Newborn ; Humans ; Infant, Premature ; Retrospective Studies ; Infant, Very Low Birth Weight ; Infant, Premature, Diseases/etiology ; Time Factors ; Enterocolitis, Necrotizing/diagnosis ; Enterocolitis, Necrotizing/epidemiology ; Enterocolitis, Necrotizing/etiology ; Birth Weight |
| Sprache | Englisch |
| Erscheinungsdatum | 2023-01-25 |
| Erscheinungsland | United States |
| Dokumenttyp | Journal Article |
| ZDB-ID | 603201-1 |
| ISSN | 1536-4801 ; 0277-2116 |
| ISSN (online) | 1536-4801 |
| ISSN | 0277-2116 |
| DOI | 10.1097/MPG.0000000000003720 |
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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