LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Suchergebnis

Treffer 1 - 4 von insgesamt 4

Suchoptionen

  1. Artikel: Bloodstream Infections by AmpC-Producing Enterobacterales: Risk Factors and Therapeutic Outcome.

    Pospišil, Mladen / Car, Haris / Elveđi-Gašparović, Vesna / Beader, Nataša / Herljević, Zoran / Bedenić, Branka

    Pathogens (Basel, Switzerland)

    2023  Band 12, Heft 9

    Abstract: Bloodstream infections associated with AmpC-producing Enterobacterales are severe medical conditions which, without prompt and effective treatment, may have dire ramifications. This study aimed to assess whether certain comorbidities and previous ... ...

    Abstract Bloodstream infections associated with AmpC-producing Enterobacterales are severe medical conditions which, without prompt and effective treatment, may have dire ramifications. This study aimed to assess whether certain comorbidities and previous surgical procedures coincide with resistance determinants of AmpC-producing Enterobacterales associated with bloodstream infections. Antibiotic resistance patterns and therapy outcome were also determined. The patients' data obtained revealed that the prevalence of recent surgical procedures, solid organ tumors, metabolic diseases, kidney and liver failure, and hematological malignancies do not differ between resistant and susceptible isolates of AmpC-producing Enterobacterales. Furthermore, no difference was reported in mortality rates. Regarding antibiotic resistance, 34.52% of isolates were confirmed to be resistant (AmpC hyperproduction, ESBL, or carbapenemase). More than one in five AmpC hyperproducers were reported amid
    Sprache Englisch
    Erscheinungsdatum 2023-09-03
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12091125
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  2. Artikel: Emergence and Spread of Enterobacterales with Multiple Carbapenemases after COVID-19 Pandemic.

    Bedenić, Branka / Luxner, Josefa / Car, Haris / Sardelić, Sanda / Bogdan, Maja / Varda-Brkić, Dijana / Šuto, Sandra / Grisold, Andrea / Beader, Nataša / Zarfel, Gernot

    Pathogens (Basel, Switzerland)

    2023  Band 12, Heft 5

    Abstract: Resistance to carbapenems ... ...

    Abstract Resistance to carbapenems in
    Sprache Englisch
    Erscheinungsdatum 2023-05-03
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens12050677
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  3. Artikel ; Online: FALSE POSITIVE PHENOTYPIC DETECTION OF METALLO-BETA-LACTAMASES IN

    Bedenić, Branka / Ladavac, Ranko / Vranić-Ladavac, Mirna / Barišić, Nada / Karčić, Natalie / Sreter, Katherina Bernadette / Mihaljević, Slobodan / Bielen, Luka / Car, Haris / Beader, Nataša

    Acta clinica Croatica

    2019  Band 58, Heft 1, Seite(n) 113–118

    Abstract: Phenotypic detection of metallo-β-lactamases (MBLs) ... ...

    Abstract Phenotypic detection of metallo-β-lactamases (MBLs) in
    Mesh-Begriff(e) Acinetobacter baumannii/isolation & purification ; Bacterial Proteins/isolation & purification ; Drug Resistance, Multiple, Bacterial ; Genotyping Techniques/methods ; Humans ; Metals/metabolism ; Microbial Sensitivity Tests/methods ; Phenotype ; beta-Lactamases/isolation & purification
    Chemische Substanzen Bacterial Proteins ; Metals ; beta-Lactamases (EC 3.5.2.6) ; carbapenemase (EC 3.5.2.6) ; oxacillinase (EC 3.5.2.6)
    Sprache Englisch
    Erscheinungsdatum 2019-03-06
    Erscheinungsland Croatia
    Dokumenttyp Journal Article
    ZDB-ID 1478635-7
    ISSN 1333-9451 ; 0353-9466
    ISSN (online) 1333-9451
    ISSN 0353-9466
    DOI 10.20471/acc.2019.58.01.15
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 5057: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  4. Artikel ; Online: In vitro synergy and postantibiotic effect of colistin combinations with meropenem and vancomycin against Enterobacteriaceae with multiple carbapenem resistance mechanisms.

    Bedenić, Branka / Car, Haris / Slačanac, Domagoj / Sviben, Mario / Čačić, Marko / Lukić-Grlić, Amarela / Benčić, Ana / Šijak, Dorotea / Tripković, Marko / Beader, Nataša

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

    2018  Band 24, Heft 12, Seite(n) 1016–1019

    Abstract: Aim: The aim of the study was to determine in vitro synergy and postantibiotic effect of colistin alone and combined with meropenem or vancomycin against Enterobacteriaceae producing multiple carbapenemases; combinations of two metallo-β-lactamases (MBL) ...

    Abstract Aim: The aim of the study was to determine in vitro synergy and postantibiotic effect of colistin alone and combined with meropenem or vancomycin against Enterobacteriaceae producing multiple carbapenemases; combinations of two metallo-β-lactamases (MBL) or MBL with OXA-48. Colistin-resistant strain positive for OXA-48 was also included in the study.
    Methods: The antibiotic susceptibility was tested by broth microdilution method. Synergy was tested by chequerboard, time-kill and 2-well method. PAE was determined by viable counting.
    Results: The chequerboard analysis revealed synergy for colistin combination with meropenem in all isolates with FICI values ranging from 0.12 to 0.24. FICI values for combinations with vancomycin were below 0.5 indicating synergy in two out of four isolates. K. pneumoniae 609815 positive for OXA-48 and colistin resistant showed the most pronounced and consistent synergy effect with meropenem in both chequerboard and time-kill method. Synergy effect in time-kill curves, was observed for K pneumoniae 145846 with two MBLs and colistin resistant K. pneumoniae 609815 positive for OXA-48, with both combinations including meropenem and vancomycin. Colistin alone exhibited short postantibiotic effect (PAE) against all tested isolates. Meropenem markedly prolonged the PAE in two isolates in contrast to vancomycin which did not demonstrate significant effect on the duration of PAE.
    Conclusions: The synergy effect and the duration of PAE was strain and antibiotic dependent but not related to the resistance gene content.
    Mesh-Begriff(e) Anti-Bacterial Agents/pharmacology ; Colistin/pharmacology ; Drug Resistance, Multiple, Bacterial/drug effects ; Drug Synergism ; Enterobacter cloacae/drug effects ; Enterobacter cloacae/enzymology ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/enzymology ; Meropenem/pharmacology ; Microbial Sensitivity Tests ; Vancomycin/pharmacology ; beta-Lactam Resistance/drug effects ; beta-Lactamases/metabolism
    Chemische Substanzen Anti-Bacterial Agents ; Vancomycin (6Q205EH1VU) ; beta-Lactamases (EC 3.5.2.6) ; Meropenem (FV9J3JU8B1) ; Colistin (Z67X93HJG1)
    Sprache Englisch
    Erscheinungsdatum 2018-07-11
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 1355399-9
    ISSN 1437-7780 ; 1341-321X
    ISSN (online) 1437-7780
    ISSN 1341-321X
    DOI 10.1016/j.jiac.2018.06.001
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 5236: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

Zum Seitenanfang