Artikel ; Online: A role for Th17 cells in the immunopathogenesis of atopic dermatitis?
The Journal of investigative dermatology
2008 Band 128, Heft 11, Seite(n) 2569–2571
Abstract: Atopic dermatitis (AD) is a common inflammatory skin disease. Both epidermal barrier dysfunction and immunodysregulation are suggested to influence the pathogenesis of AD. AD has been considered a paradigmatic T helper cell (Th) 2-mediated disease, with ... ...
| Abstract | Atopic dermatitis (AD) is a common inflammatory skin disease. Both epidermal barrier dysfunction and immunodysregulation are suggested to influence the pathogenesis of AD. AD has been considered a paradigmatic T helper cell (Th) 2-mediated disease, with a switch to a Th1 cell environment during the chronic phase of the disease. Previously unreported findings now suggest a possible role for Th17 cells as well. |
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| Mesh-Begriff(e) | CD4-Positive T-Lymphocytes/immunology ; Dermatitis, Atopic/etiology ; Dermatitis, Atopic/immunology ; Disease Progression ; Humans ; Interleukin-17/metabolism ; Severity of Illness Index ; T-Lymphocytes, Helper-Inducer/metabolism ; Th1 Cells/metabolism ; Th2 Cells/metabolism | |||||
| Chemische Substanzen | Interleukin-17 | |||||
| Sprache | Englisch | |||||
| Erscheinungsdatum | 2008-10-09 | |||||
| Erscheinungsland | United States | |||||
| Dokumenttyp | Comment ; Journal Article | |||||
| ZDB-ID | 80136-7 | |||||
| ISSN | 1523-1747 ; 0022-202X | |||||
| ISSN (online) | 1523-1747 | |||||
| ISSN | 0022-202X | |||||
| DOI | 10.1038/jid.2008.283 | |||||
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| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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