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  1. Artikel: MAIT Cells Modulate Innate Immune Cells and Inhibit Colon Cancer Growth.

    Cheng, Olivia J / Lebish, Eric J / Jensen, Owen / Jacenik, Damian / Trivedi, Shubhanshi / Cacioppo, Jackson / Aubé, Jeffrey / Beswick, Ellen J / Leung, Daniel T

    bioRxiv : the preprint server for biology

    2024  

    Abstract: Mucosal-associated invariant T (MAIT) cells are innate-like T cells that can be activated by microbial antigens and cytokines and are abundant in mucosal tissues including the colon. MAIT cells have cytotoxic and pro-inflammatory functions and have ... ...

    Abstract Mucosal-associated invariant T (MAIT) cells are innate-like T cells that can be activated by microbial antigens and cytokines and are abundant in mucosal tissues including the colon. MAIT cells have cytotoxic and pro-inflammatory functions and have potentials for use as adoptive cell therapy. However, studies into their anti-cancer activity, including their role in colon cancer, are limited. Using an animal model of colon cancer, we show that peritumoral injection of
    Sprache Englisch
    Erscheinungsdatum 2024-02-02
    Erscheinungsland United States
    Dokumenttyp Preprint
    DOI 10.1101/2024.01.16.575894
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Mucosal-associated invariant T cells modulate innate immune cells and inhibit colon cancer growth.

    Cheng, Olivia J / Lebish, Eric J / Jensen, Owen / Jacenik, Damian / Trivedi, Shubhanshi / Cacioppo, Jackson G / Aubé, Jeffrey / Beswick, Ellen J / Leung, Daniel T

    Scandinavian journal of immunology

    2024  , Seite(n) e13391

    Abstract: Mucosal-associated invariant T (MAIT) cells are innate-like T cells that can be activated by microbial antigens and cytokines and are abundant in mucosal tissues including the colon. MAIT cells have cytotoxic and pro-inflammatory functions and have ... ...

    Abstract Mucosal-associated invariant T (MAIT) cells are innate-like T cells that can be activated by microbial antigens and cytokines and are abundant in mucosal tissues including the colon. MAIT cells have cytotoxic and pro-inflammatory functions and have potentials for use as adoptive cell therapy. However, studies into their anti-cancer activity, including their role in colon cancer, are limited. Using an animal model of colon cancer, we showed that peritumoral injection of in vivo-expanded MAIT cells into RAG1
    Sprache Englisch
    Erscheinungsdatum 2024-05-21
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 120476-2
    ISSN 1365-3083 ; 0300-9475
    ISSN (online) 1365-3083
    ISSN 0300-9475
    DOI 10.1111/sji.13391
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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