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  1. Artikel ; Online: Biofabricated selenium nanoparticles mediated from Goniothalamus wightii gains biomedical applications and photocatalytic degrading ability

    Chinnaraj Santhosh / Balamuralikrishnan Balasubramanian / Palani Vino / Maluventhen Viji / Chandrababu Rejeeth / Soundarapandian Kannan / Hammad Ullah / Kannan R.R. Rengasamy / Maria Daglia / Arumugam Maruthupandian

    Journal of King Saud University: Science, Vol 34, Iss 8, Pp 102331- (2022)

    2022  

    Abstract: Selenium nanoparticles (SeNPs) have attracted recently in different biomedical applications due to its unique role of metabolic function prevents cellular damage and other severe disease of human. In this study, biosynthesis of SeNPs from Goniothalamus ... ...

    Abstract Selenium nanoparticles (SeNPs) have attracted recently in different biomedical applications due to its unique role of metabolic function prevents cellular damage and other severe disease of human. In this study, biosynthesis of SeNPs from Goniothalamus wightii (Gw-SeNPs) and characterization were performed on UV–vis spectroscopy showed at 265 nm, it was primarily confirmed the biosynthesis of SeNPs. The XRD pattern revealed that peaks at 29.98 (101), 33.22 (111), 47.42 (200), 65.38 (220) and 77.40 (311)) exhibited a highly crystalline structure. The FE-SEM image proved that the formation of Gw-SeNPs which were polygonal shape. Zeta potential and DLS value of SeNPs recorded as −17.6 mV and 20–110 nm. The results described the synthesized SeNPs have good antibacterial potential on both strains of gram-positive as well as gram-negative pathogens. In vitro antioxidant ability of biogenic Gw-SeNPs has been assessed the inhibition of DPPH free radical scavenging ability with IC50 value was reported as 75.62 (µg/mL) and ABTS inhibitory concentration at 50% was 74.12 (µg/mL). The present findings provide important evidence on cytotoxic effects of Gw-SeNPs on MCF-7 cells. Dye degradation ability of Gw-SeNPs against reactive dyes over the 97% in 150 min in methylene blue dye degradation, the experiment was done under the direct sunlight. Finally, the larvicidal activity against fourth instars mosquito larvae was also executed. In this study, the data indicate that biosynthesis of Gw-SeNPs strongly performed a significant and multifunctional role in biomedical and environmental field.
    Schlagwörter Gw-SeNPs ; Anticancer activity ; Methylene blue ; Antioxidant ; Larvicidal activity ; Science (General) ; Q1-390
    Thema/Rubrik (Code) 500
    Sprache Englisch
    Erscheinungsdatum 2022-11-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Derivation, Functionalization of (S)-Goniothalamin from

    Palani, Vino / Chinnaraj, Santhosh / Shanmugasundaram, Murugesh / Malaisamy, Arunkumar / Maluventhen, Viji / Arumugam, Vijaya Anand / Rengasamy, Kannan R R / Balasubramanian, Balamuralikrishnan / Liu, Wen-Chao / Arumugam, Maruthupandian

    Molecules (Basel, Switzerland)

    2022  Band 27, Heft 20

    Abstract: The tracing of an alternative drug, Phytochemicals is a promising approach to the viral threats that have emerged over the past two years. Across the world, herbal medicine is a better solution against anti-viral diseases during pandemic periods. ...

    Abstract The tracing of an alternative drug, Phytochemicals is a promising approach to the viral threats that have emerged over the past two years. Across the world, herbal medicine is a better solution against anti-viral diseases during pandemic periods.
    Mesh-Begriff(e) Humans ; SARS-CoV-2 ; Goniothalamus ; COVID-19/drug therapy ; Coronavirus 3C Proteases ; Antioxidants ; Spectroscopy, Fourier Transform Infrared ; Cysteine Endopeptidases/chemistry ; Antiviral Agents/chemistry ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; RNA-Dependent RNA Polymerase
    Chemische Substanzen goniothalamin (34W9GO6B2Z) ; Coronavirus 3C Proteases (EC 3.4.22.28) ; Antioxidants ; Cysteine Endopeptidases (EC 3.4.22.-) ; Antiviral Agents ; RNA-Dependent RNA Polymerase (EC 2.7.7.48)
    Sprache Englisch
    Erscheinungsdatum 2022-10-17
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules27206962
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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