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  1. Artikel ; Online: Calculated parameters of luminal esophageal temperatures predict esophageal injury following conventional and high-power short-duration radiofrequency pulmonary vein isolation.

    Grosse Meininghaus, Dirk / Freund, Robert / Kleemann, Tobias / Christoph Geller, J

    Journal of cardiovascular electrophysiology

    2022  Band 33, Heft 6, Seite(n) 1167–1176

    Abstract: Background: Luminal esophageal temperature (LET) monitoring is not associated with reduced esophageal injury following pulmonary vein isolation (PVI).: Objective: Detailed analysis of (the temporal and spatial gradients of) LET measurements may ... ...

    Abstract Background: Luminal esophageal temperature (LET) monitoring is not associated with reduced esophageal injury following pulmonary vein isolation (PVI).
    Objective: Detailed analysis of (the temporal and spatial gradients of) LET measurements may better predict the risk for esophageal injury.
    Methods: Between January 2020 and December 2021, LET maxima, duration of LET rise above baseline, and area under the LET curve (AUC) were calculated offline and correlated with (endoscopy and endoscopic ultrasound detected) esophageal injury (i.e., mucosal esophageal lesions [ELs], periesophageal edema, and gastric motility disorders) following PVI using moderate-power moderate-duration (MPMD [25-30 W/25-30s]) and high-power short-duration (HPSD [50 W/13s]) radiofrequency (RF) settings.
    Results: 63 patients (69 ± 9 years old, 32 male, 51 MPMD and 12 HPSD) were studied. The esophageal injury was frequent (40% in both groups), mucosal ELs were more common with MPMD, and edema was frequently observed following HPSD. RF-duration, total RF-energy at the left atrial (LA) posterior wall, and distance between LA and esophagus were not different between patients with/without esophageal injury. In contrast, to LET and LET duration above baseline, AUC was the best predictor and significantly increased in patients with esophageal injury (3422 vs. 2444 K
    Conclusion: For both ablation strategies, AUC of the LET curves best predicted esophageal injury. HPSD is associated with similar rates of esophageal injury when (mostly subclinical) periesophageal alterations (that are of unclear clinical relevance) are included. Whether integration of these calculated LET parameters is useful to prevent esophageal injury remains to be seen.
    Mesh-Begriff(e) Aged ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/surgery ; Body Temperature ; Catheter Ablation/adverse effects ; Humans ; Male ; Middle Aged ; Pulmonary Veins/surgery ; Temperature ; Treatment Outcome
    Sprache Englisch
    Erscheinungsdatum 2022-04-30
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.15509
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Ablation of atrial fibrillation: surgery may show the way.

    Christoph Geller, Johann / Kuntze, Thomas

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2018  Band 20, Heft FI_3, Seite(n) f282–f283

    Mesh-Begriff(e) Atrial Fibrillation/surgery ; Catheter Ablation ; Humans ; Mitral Valve/surgery
    Sprache Englisch
    Erscheinungsdatum 2018-01-07
    Erscheinungsland England
    Dokumenttyp Editorial ; Comment
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/eux309
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: A case of Prinzmetal angina diagnosed by Holter monitoring who survived a sudden cardiac death: Case report.

    Farah, Ahmed / Ohlow, Marc-Alexander / Kühn, Bettina / Frommhold, Markus / Lotze, Ulrich / Christoph Geller, J / Lauer, Bernward

    Journal of cardiology cases

    2012  Band 6, Heft 3, Seite(n) e88–e90

    Abstract: A 47-year-old female patient was admitted to our hospital after a syncope. She reported episodes of angina in previous weeks. On admission, there were no electrocardiographic changes but elevated troponin. Coronary angiogram showed minimal ... ...

    Abstract A 47-year-old female patient was admitted to our hospital after a syncope. She reported episodes of angina in previous weeks. On admission, there were no electrocardiographic changes but elevated troponin. Coronary angiogram showed minimal arteriosclerosis and normal left ventricle. Holter monitoring showed severe ST-segment changes during an anginal episode.With calcium antagonists, the patient experienced no further episodes of angina or ST changes during telemetry.Six weeks later, calcium antagonist was stopped for unknown reason. After that, the patient experienced a second prolonged syncope with cardiopulmonary resuscitation and defibrillation of ventricular fibrillation.
    Discussion: "A variant form of angina pectoris" was first described by Myron Prinzmetal. He postulated coronary vasospasm as the underlying cause, however, after 50 years the exact pathophysiology is still not known.Patients with "variant angina" usually present with "spontaneous" attacks of typical retrosternal anginal pain during rest or normal activities, but not with physical exercise.Sudden cardiac deaths were reported in patients with Prinzmetal angina in only a few case reports.
    Conclusion: In cases of variant angina accompanied by syncope, a provocation test and an electrophysiological study should be considered.
    Sprache Englisch
    Erscheinungsdatum 2012-07-21
    Erscheinungsland Japan
    Dokumenttyp Case Reports
    ISSN 1878-5409
    ISSN (online) 1878-5409
    DOI 10.1016/j.jccase.2012.06.001
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Remote monitoring and clinical outcomes: details on information flow and workflow in the IN-TIME study.

    Husser, Daniela / Christoph Geller, Johann / Taborsky, Miloš / Schomburg, Rolf / Bode, Frank / Nielsen, Jens Cosedis / Stellbrink, Christoph / Meincke, Carsten / Hjortshøj, Søren Pihlkjær / Schrader, Jürgen / Lewalter, Thorsten / Hindricks, Gerhard

    European heart journal. Quality of care & clinical outcomes

    2018  Band 5, Heft 2, Seite(n) 136–144

    Abstract: Aims: Randomized clinical trials investigating a possible outcome effect of remote monitoring in patients with implantable defibrillators have shown conflicting results. This study analyses the information flow and workflow details from the IN-TIME ... ...

    Abstract Aims: Randomized clinical trials investigating a possible outcome effect of remote monitoring in patients with implantable defibrillators have shown conflicting results. This study analyses the information flow and workflow details from the IN-TIME study and discusses whether differences of message content, information speed and completeness, and workflow may contribute to the heterogeneous results.
    Methods and results: IN-TIME randomized 664 patients with an implantable cardioverter/defibrillator indication to daily remote monitoring vs. control. After 12 months, a composite clinical score and all-cause mortality were improved in the remote monitoring arm. Messages were received on 83.1% of out-of-hospital days. Daily transmissions were interrupted 2.3 times per patient-year for more than 3 days. During 1 year, absolute transmission success declined by 3.3%. Information on medical events was available after 1 day (3 days) in 83.1% (94.3%) of the cases. On all working days, a central monitoring unit informed investigators of protocol defined events. Investigators contacted patients with a median delay of 1 day and arranged follow-ups, the majority of which took place within 1 week of the event being available.
    Conclusion: Only limited data on the information flow and workflow have been published from other studies which failed to improve outcome. However, a comparison of those data to IN-TIME suggest that the ability to see a patient early after clinical events may be inferior to the set-up in IN-TIME. These differences may be responsible for the heterogeneity found in clinical effectiveness of remote monitoring concepts.
    Mesh-Begriff(e) Defibrillators, Implantable ; Female ; Follow-Up Studies ; Heart Failure/diagnosis ; Heart Failure/physiopathology ; Heart Failure/therapy ; Humans ; Male ; Monitoring, Ambulatory/methods ; Remote Sensing Technology/methods ; Reproducibility of Results ; Time Factors ; Time and Motion Studies ; Treatment Outcome ; Workflow
    Sprache Englisch
    Erscheinungsdatum 2018-07-17
    Erscheinungsland England
    Dokumenttyp Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2823451-0
    ISSN 2058-1742 ; 2058-5225
    ISSN (online) 2058-1742
    ISSN 2058-5225
    DOI 10.1093/ehjqcco/qcy031
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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