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  1. Artikel: Letter from Samuel Cole, M.D., Heidelberg.

    Cole, Samuel

    The Chicago medical journal

    2023  Band 25, Heft 9, Seite(n) 300–308

    Sprache Englisch
    Erscheinungsdatum 2023-07-06
    Erscheinungsland United States
    Dokumenttyp Journal Article
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Letter from Vienna.

    Cole, Samuel

    The Chicago medical journal

    2023  Band 25, Heft 10, Seite(n) 323–326

    Sprache Englisch
    Erscheinungsdatum 2023-07-06
    Erscheinungsland United States
    Dokumenttyp Journal Article
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: The price of COVID-19 risk in a public university.

    Altindag, Duha T / Cole, Samuel / Seals, R Alan

    Economics of education review

    2023  Band 94, Seite(n) 102410

    Abstract: We study the allocation of and compensation for occupational COVID-19 risk at Auburn University, a large public university in the U.S. In Spring 2021, approximately half of the face-to-face classes had enrollments above the legal capacity allowed by a ... ...

    Abstract We study the allocation of and compensation for occupational COVID-19 risk at Auburn University, a large public university in the U.S. In Spring 2021, approximately half of the face-to-face classes had enrollments above the legal capacity allowed by a public health order, which followed CDC's social distancing guidelines. We find lower-ranked graduate student teaching assistants and adjunct instructors were more likely to deliver riskier classes. Using an IV strategy in which teaching risk is shifted by classroom features (geometry and furniture), we show instructors who taught at least one risky class earned $7,400 more than those who did not.
    Sprache Englisch
    Erscheinungsdatum 2023-05-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 0272-7757
    ISSN 0272-7757
    DOI 10.1016/j.econedurev.2023.102410
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Robotic Nerve Surgery: Brachial Plexus.

    Parham, Matthew J / Cole, Samuel H / Yim, Nicholas H / Pederson, William C

    Seminars in plastic surgery

    2023  Band 37, Heft 3, Seite(n) 199–205

    Abstract: Management of closed brachial plexus injuries has traditionally favored conservative approaches with lengthy intervals between initial injury and surgical reconstruction. The complex anatomy of this region often requires large incisions with extensive ... ...

    Abstract Management of closed brachial plexus injuries has traditionally favored conservative approaches with lengthy intervals between initial injury and surgical reconstruction. The complex anatomy of this region often requires large incisions with extensive dissection. Recently, the use of robotic systems in plastic and reconstructive surgery has been increasing, and robot-assisted brachial plexus reconstruction is a novel application that is currently being explored. Current literature describing this application is primarily comprised of feasibility studies using animal and cadaver models, and literature describing use in human subjects is limited. Advantages demonstrated by these early studies include the reduction of physiologic tremor, 3D visualization of anatomical structures, and ergonomic positioning; this allows for increased surgical dexterity and the ability to perform minimally invasive microsurgical procedures within the confined anatomical spaces of the brachial plexus. Limitations revolve around inadequate instrumentation, large learning curves, and increased costs that restrict the ability to perform these complex microsurgical procedures reliably and efficiently. As companies continue to develop instrumentation specific to robot-assisted microsurgery, more extensive longitudinal studies outlining long-term costs, changes in operating time, and functional outcomes will be required before a conclusion about the utility of these systems in brachial plexus surgery can be made.
    Sprache Englisch
    Erscheinungsdatum 2023-09-18
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2077828-4
    ISSN 1535-2188
    ISSN 1535-2188
    DOI 10.1055/s-0043-1772847
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Common Pediatric Hand Anomalies.

    McCarter, Jacob H / Zeledon, Ricardo A / Cole, Samuel H / Layon, Sarah A / Nguyen, Jenny Lee

    Seminars in plastic surgery

    2023  Band 37, Heft 4, Seite(n) 275–286

    Abstract: Upper extremity congenital anomalies in the newborn are second only to congenital heart anomalies. Some of the more commonly encountered upper extremity anomalies are trigger thumb, thumb hypoplasia, polydactyly, syndactyly, and amniotic band syndrome. ... ...

    Abstract Upper extremity congenital anomalies in the newborn are second only to congenital heart anomalies. Some of the more commonly encountered upper extremity anomalies are trigger thumb, thumb hypoplasia, polydactyly, syndactyly, and amniotic band syndrome. While some conditions occur in isolation, others are known to commonly occur in association with syndromes. Familiarity with these conditions is important not only to provide adequate evaluation and workup of these patients but also to deliver appropriate surgical intervention and prepare parents with appropriate expectations. In this article, we outline the etiology, classification, surgical management, and outcomes of these five commonly encountered upper extremity congenital anomalies.
    Sprache Englisch
    Erscheinungsdatum 2023-11-28
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2077828-4
    ISSN 1535-2188
    ISSN 1535-2188
    DOI 10.1055/s-0043-1777096
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Robotic Nerve Surgery: Brachial Plexus

    Parham, Matthew J. / Cole, Samuel H. / Yim, Nicholas H. / Pederson, William C.

    Seminars in Plastic Surgery

    (New and Updated Applications for Robotic Surgery in Plastic Surgery)

    2023  Band 37, Heft 03, Seite(n) 199–205

    Abstract: Management of closed brachial plexus injuries has traditionally favored conservative approaches with lengthy intervals between initial injury and surgical reconstruction. The complex anatomy of this region often requires large incisions with extensive ... ...

    Serientitel New and Updated Applications for Robotic Surgery in Plastic Surgery
    Abstract Management of closed brachial plexus injuries has traditionally favored conservative approaches with lengthy intervals between initial injury and surgical reconstruction. The complex anatomy of this region often requires large incisions with extensive dissection. Recently, the use of robotic systems in plastic and reconstructive surgery has been increasing, and robot-assisted brachial plexus reconstruction is a novel application that is currently being explored. Current literature describing this application is primarily comprised of feasibility studies using animal and cadaver models, and literature describing use in human subjects is limited. Advantages demonstrated by these early studies include the reduction of physiologic tremor, 3D visualization of anatomical structures, and ergonomic positioning; this allows for increased surgical dexterity and the ability to perform minimally invasive microsurgical procedures within the confined anatomical spaces of the brachial plexus. Limitations revolve around inadequate instrumentation, large learning curves, and increased costs that restrict the ability to perform these complex microsurgical procedures reliably and efficiently. As companies continue to develop instrumentation specific to robot-assisted microsurgery, more extensive longitudinal studies outlining long-term costs, changes in operating time, and functional outcomes will be required before a conclusion about the utility of these systems in brachial plexus surgery can be made.
    Schlagwörter plastic surgery ; robotic surgery ; brachial plexus
    Sprache Englisch
    Erscheinungsdatum 2023-08-01
    Verlag Thieme Medical Publishers, Inc.
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel
    ZDB-ID 2077828-4
    ISSN 1536-0067 ; 1535-2188
    ISSN (online) 1536-0067
    ISSN 1535-2188
    DOI 10.1055/s-0043-1772847
    Datenquelle Thieme Verlag

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  7. Artikel ; Online: Effect of hyperglycaemia in combination with moxifloxacin on cardiac repolarization in male and female patients with type I diabetes.

    Taubel, Jorg / Pimenta, Dominic / Cole, Samuel Thomas / Graff, Claus / Kanters, Jørgen K / Camm, A John

    Clinical research in cardiology : official journal of the German Cardiac Society

    2022  Band 111, Heft 10, Seite(n) 1147–1160

    Abstract: Background: Patients with Type 1 diabetes mellitus have been shown to be at a two to ten-fold higher risk of sudden cardiac death (SCD) (Svane et al., Curr Cardiol 2020; 22:112) than the general population, but the underlying mechanism is unclear. ... ...

    Abstract Background: Patients with Type 1 diabetes mellitus have been shown to be at a two to ten-fold higher risk of sudden cardiac death (SCD) (Svane et al., Curr Cardiol 2020; 22:112) than the general population, but the underlying mechanism is unclear. Hyperglycaemia is a recognised cause of QTc prolongation; a state patients with type 1 diabetes are more prone to, potentially increasing their risk of ventricular arrhythmia. Understanding the QTc prolongation effect of both hyperglycaemia and the concomitant additive risk of commonly prescribed QTc-prolonging drugs such as Moxifloxacin may help to elucidate the mechanism of sudden cardiac death in this cohort. This single-blinded, placebo-controlled study investigated the extent to which hyperglycaemia prolongs the QTc in controlled conditions, and the potential additive risk of QTc-prolonging medications.
    Methods: 21 patients with type 1 diabetes mellitus were enrolled to a placebo-controlled crossover study at a single clinical trials unit. Patients underwent thorough QTc assessment throughout the study. A 'hyperglycaemic clamp' of oral and intravenous glucose was administered with a target blood glucose of > 25 mM and maintained for 2 h on day 1 and day 3, alongside placebo on day 1 and moxifloxacin on day 3. Day 2 served as a control day between the two active treatment days. Thorough QTc assessment was conducted at matched time points over 3 days, and regular blood sampling was undertaken at matched time intervals for glucose levels and moxifloxacin exposure.
    Results: Concentration-effect modelling showed that acute hyperglycaemia prolonged the QTc interval in female and male volunteers with type 1 diabetes by a peak mean increase of 13 ms at 2 h. Peak mean QTc intervals after the administration of intravenous Moxifloxacin during the hyperglycaemic state were increased by a further 9 ms at 2 h, to 22 ms across the entire study population. Regression analysis suggested this additional increase was additive, not exponential. Hyperglycaemia was associated with a significantly greater mean QTc-prolonging effect in females, but the mean peak increase with the addition of moxifloxacin was the same for males and females. This apparent sex difference was likely due to the exclusive use of basal insulin in the male patients, which provided a low level of exogenous insulin during the study assessments thereby mitigating the effects of hyperglycaemia on QTc. This effect was partially overcome by Moxifloxacin administration, suggesting both hyperglycaemia and moxifloxacin prolong QTc by different mechanisms, based on subinterval analysis.
    Conclusions: Hyperglycaemia was found to be a significant cause of QTc prolongation and the additional effect of a QTc-prolonging positive control (moxifloxacin) was found to be additive. Given the high risk of sudden cardiac death in type 1 diabetes mellitus, extra caution should be exercised when prescribing any medication in this cohort for QTc effects, and further research needs to be undertaken to elucidate the exact mechanism underlying this finding and explore the potential prescribing risk in diabetes.
    Trial registration: NCT number: NCT01984827.
    Mesh-Begriff(e) Blood Glucose ; Cross-Over Studies ; Death, Sudden, Cardiac ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/drug therapy ; Double-Blind Method ; Female ; Heart Rate ; Humans ; Hyperglycemia/complications ; Hyperglycemia/drug therapy ; Insulins/pharmacology ; Long QT Syndrome ; Male ; Moxifloxacin/adverse effects
    Chemische Substanzen Blood Glucose ; Insulins ; Moxifloxacin (U188XYD42P)
    Sprache Englisch
    Erscheinungsdatum 2022-05-21
    Erscheinungsland Germany
    Dokumenttyp Journal Article ; Randomized Controlled Trial
    ZDB-ID 2213295-8
    ISSN 1861-0692 ; 1861-0684
    ISSN (online) 1861-0692
    ISSN 1861-0684
    DOI 10.1007/s00392-022-02037-8
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Buch ; Online: The Distribution of Occupational Tasks in the United States

    Cole, Samuel / Cowell, Zachary / Nunley, John M. / Seals Jr, R. Alan

    Implications for a Diverse and Aging Population

    2022  

    Abstract: We document the age-race-gender intersectionality in the distribution of occupational tasks in the United States. We also investigate how the task content of work changed from the early-2000s to the late-2010s for different age-race/ethnicity-gender ... ...

    Abstract We document the age-race-gender intersectionality in the distribution of occupational tasks in the United States. We also investigate how the task content of work changed from the early-2000s to the late-2010s for different age-race/ethnicity-gender groups. Using the Occupation Information Network (O*NET) and pooled cross-sectional data from the American Community Survey (ACS) we examine how the tasks that workers perform vary with age and over time. We find that White men transition to occupations high in non-routine cognitive tasks early in their careers, whereas Hispanic and Black men work mostly in physically demanding jobs over their entire working lives. Routine manual tasks increased dramatically for 55-67 year-old workers, except for Asian men and women. Policymakers will soon be challenged by financial stress on entitlement programs, reforms could have disproportionate effects on gender and racial/ethnic groups due to inequality in the distribution of occupational tasks.
    Schlagwörter Economics - General Economics
    Thema/Rubrik (Code) 331
    Erscheinungsdatum 2022-05-01
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel: Common Pediatric Hand Anomalies

    McCarter, Jacob H. / Zeledon, Ricardo A. / Cole, Samuel H. / Layon, Sarah A. / Nguyen, Jenny Lee

    Seminars in Plastic Surgery

    (Pediatric Plastic Surgery)

    2023  Band 37, Heft 04, Seite(n) 275–286

    Abstract: Upper extremity congenital anomalies in the newborn are second only to congenital heart anomalies. Some of the more commonly encountered upper extremity anomalies are trigger thumb, thumb hypoplasia, polydactyly, syndactyly, and amniotic band syndrome. ... ...

    Serientitel Pediatric Plastic Surgery
    Abstract Upper extremity congenital anomalies in the newborn are second only to congenital heart anomalies. Some of the more commonly encountered upper extremity anomalies are trigger thumb, thumb hypoplasia, polydactyly, syndactyly, and amniotic band syndrome. While some conditions occur in isolation, others are known to commonly occur in association with syndromes. Familiarity with these conditions is important not only to provide adequate evaluation and workup of these patients but also to deliver appropriate surgical intervention and prepare parents with appropriate expectations. In this article, we outline the etiology, classification, surgical management, and outcomes of these five commonly encountered upper extremity congenital anomalies.
    Schlagwörter upper extremity ; congenital hand ; thumb hypoplasia ; syndactyly ; trigger thumb ; amniotic band syndrome ; polydactyly
    Sprache Englisch
    Erscheinungsdatum 2023-11-01
    Verlag Thieme Medical Publishers, Inc.
    Erscheinungsort Stuttgart ; New York
    Dokumenttyp Artikel
    ZDB-ID 2077828-4
    ISSN 1536-0067 ; 1535-2188
    ISSN (online) 1536-0067
    ISSN 1535-2188
    DOI 10.1055/s-0043-1777096
    Datenquelle Thieme Verlag

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  10. Artikel: Pre-HIV Test Counseling and the Perpetuation of Stigma.

    Cole, Samuel Thomas / Hart, Kayleigh Zoe

    Journal of the International Association of Providers of AIDS Care

    2015  Band 14, Heft 3, Seite(n) 196

    Mesh-Begriff(e) Counseling ; HIV Infections/diagnosis ; HIV Infections/psychology ; Humans ; Mass Screening/psychology ; Social Stigma
    Sprache Englisch
    Erscheinungsdatum 2015-05
    Erscheinungsland United States
    Dokumenttyp Letter
    ZDB-ID 2709037-1
    ISSN 2325-9582 ; 2325-9574
    ISSN (online) 2325-9582
    ISSN 2325-9574
    DOI 10.1177/2325957415570741
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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