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  1. Artikel: The Dynamic Motor Control Index as a Marker of Age-Related Neuromuscular Impairment.

    Collimore, Ashley N / Aiello, Ashlyn J / Pohlig, Ryan T / Awad, Louis N

    Frontiers in aging neuroscience

    2021  Band 13, Seite(n) 678525

    Abstract: Biomarkers that can identify age-related decline in walking function have potential to promote healthier aging by triggering timely interventions that can mitigate or reverse impairments. Recent evidence suggests that changes in neuromuscular control ... ...

    Abstract Biomarkers that can identify age-related decline in walking function have potential to promote healthier aging by triggering timely interventions that can mitigate or reverse impairments. Recent evidence suggests that changes in neuromuscular control precede changes in walking function; however, it is unclear which measures are best suited for identifying age-related changes. In this study, non-negative matrix factorization of electromyography data collected during treadmill walking was used to calculate two measures of the complexity of muscle co-activations during walking for 36 adults: (1) the number of muscle synergies and (2) the dynamic motor control index. Study participants were grouped into young (18-35 years old), young-old (65-74 years old), and old-old (75+ years old) subsets. We found that the dynamic motor control index [χ
    Sprache Englisch
    Erscheinungsdatum 2021-07-22
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2558898-9
    ISSN 1663-4365
    ISSN 1663-4365
    DOI 10.3389/fnagi.2021.678525
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Enhancing Neuroplasticity in the Chronic Phase After Stroke: Effects of a Soft Robotic Exosuit on Training Intensity and Brain-Derived Neurotrophic Factor.

    Cataldo, Anna V Roto / Collimore, Ashley N / Spangler, Johanna / Ribeirinha-Braga, Lillian / Hutchinson, Karen / Wang, Qing Mei / Thompson, LaDora / Awad, Louis N

    IEEE open journal of engineering in medicine and biology

    2023  Band 4, Seite(n) 284–291

    Abstract: Objective: ...

    Abstract Objective:
    Sprache Englisch
    Erscheinungsdatum 2023-09-08
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 2644-1276
    ISSN (online) 2644-1276
    DOI 10.1109/OJEMB.2023.3313396
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Autonomous Control of Music to Retrain Walking After Stroke.

    Collimore, Ashley N / Roto Cataldo, Anna V / Aiello, Ashlyn J / Sloutsky, Regina / Hutchinson, Karen J / Harris, Brian / Ellis, Terry / Awad, Louis N

    Neurorehabilitation and neural repair

    2023  Band 37, Heft 5, Seite(n) 255–265

    Abstract: Background: Post-stroke care guidelines highlight continued rehabilitation as essential; however, many stroke survivors cannot participate in outpatient rehabilitation. Technological advances in wearable sensing, treatment algorithms, and care delivery ... ...

    Abstract Background: Post-stroke care guidelines highlight continued rehabilitation as essential; however, many stroke survivors cannot participate in outpatient rehabilitation. Technological advances in wearable sensing, treatment algorithms, and care delivery interfaces have created new opportunities for high-efficacy rehabilitation interventions to be delivered autonomously in any setting (ie, clinic, community, or home).
    Methods: We developed an autonomous rehabilitation system that combines the closed-loop control of music with real-time gait analysis to fully automate patient-tailored walking rehabilitation. Specifically, the mechanism-of-action of auditory-motor entrainment is applied to induce targeted changes in the post-stroke gait pattern by way of targeted changes in music. Using speed-controlled biomechanical and physiological assessments, we evaluate in 10 individuals with chronic post-stroke hemiparesis the effects of a fully-automated gait training session on gait asymmetry and the energetic cost of walking.
    Results: Post-treatment reductions in step time (Δ: -12 ± 26%,
    Conclusions: The closed-loop control of music can fully automate walking rehabilitation that markedly improves walking after stroke. Autonomous rehabilitation delivery systems that can safely provide high-efficacy rehabilitation in any setting have the potential to alleviate access-related care gaps and improve long-term outcomes after stroke.
    Mesh-Begriff(e) Humans ; Aged ; Stroke Rehabilitation ; Music ; Stroke ; Walking/physiology ; Gait/physiology ; Gait Disorders, Neurologic/rehabilitation
    Sprache Englisch
    Erscheinungsdatum 2023-06-05
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1491637-x
    ISSN 1552-6844 ; 1545-9683 ; 0888-4390
    ISSN (online) 1552-6844
    ISSN 1545-9683 ; 0888-4390
    DOI 10.1177/15459683231174223
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: A Portable, Neurostimulation-Integrated, Force Measurement Platform for the Clinical Assessment of Plantarflexor Central Drive.

    Collimore, Ashley N / Alvarez, Jonathan T / Sherman, David A / Gerez, Lucas F / Barrow, Noah / Choe, Dabin K / Binder-Macleod, Stuart / Walsh, Conor J / Awad, Louis N

    Bioengineering (Basel, Switzerland)

    2024  Band 11, Heft 2

    Abstract: Plantarflexor central drive is a promising biomarker of neuromotor impairment; however, routine clinical assessment is hindered by the unavailability of force measurement systems with integrated neurostimulation capabilities. In this study, we evaluate ... ...

    Abstract Plantarflexor central drive is a promising biomarker of neuromotor impairment; however, routine clinical assessment is hindered by the unavailability of force measurement systems with integrated neurostimulation capabilities. In this study, we evaluate the accuracy of a portable, neurostimulation-integrated, plantarflexor force measurement system we developed to facilitate the assessment of plantarflexor neuromotor function in clinical settings. Two experiments were conducted with the Central Drive System (CEDRS). To evaluate accuracy, experiment #1 included 16 neurotypical adults and used intra-class correlation (ICC
    Sprache Englisch
    Erscheinungsdatum 2024-01-30
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering11020137
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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