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  1. Artikel ; Online: Letter regarding "Evaluation of the clinical outcome of hypercalcemia of malignancy and concurrent azotemia in dogs with lymphoma".

    Couto, C Guillermo / Chew, Dennis J

    Journal of veterinary internal medicine

    2024  Band 38, Heft 3, Seite(n) 1287–1288

    Mesh-Begriff(e) Animals ; Dogs ; Dog Diseases ; Hypercalcemia/veterinary ; Azotemia/veterinary ; Azotemia/blood ; Lymphoma/veterinary ; Lymphoma/complications
    Sprache Englisch
    Erscheinungsdatum 2024-03-29
    Erscheinungsland United States
    Dokumenttyp Letter
    ZDB-ID 92798-3
    ISSN 1939-1676 ; 0891-6640
    ISSN (online) 1939-1676
    ISSN 0891-6640
    DOI 10.1111/jvim.17060
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Retrospective analysis of canine fecal flotation and coproantigen immunoassay hookworm positive results in Greyhounds and other dog breeds.

    Burton, K Wade / Hegarty, Evan / Couto, C Guillermo

    Veterinary parasitology, regional studies and reports

    2024  Band 51, Seite(n) 101026

    Abstract: Recent studies demonstrated that Greyhounds are commonly infected with Ancylostoma caninum and these infections have been shown to be resistant to anthelmintics. This study evaluated samples submitted to a commercial reference laboratory (IDEXX ... ...

    Abstract Recent studies demonstrated that Greyhounds are commonly infected with Ancylostoma caninum and these infections have been shown to be resistant to anthelmintics. This study evaluated samples submitted to a commercial reference laboratory (IDEXX Laboratories) for canine fecal flotation zinc sulfate centrifugation and coproantigen immunoassay between January 1, 2019, and July 30, 2023 for evidence that Greyhounds were more often positive for Ancylostoma spp. (hookworms) compared to other breeds. The purpose of the study was to determine if Greyhounds were more likely to be hookworm-positive compared to other breeds, if Greyhounds on preventives with efficacy against hookworm infections are more likely to test positive than other breeds, if their infections take longer to resolve, to estimate how long this takes and to assess whether the proportion of hookworm positive tests for all breeds is increasing over time. Records of 25,440,055 fecal results were obtained representing 17,671,724 unique dogs. Of these, 49,795 (∼0.3%) were Greyhounds. The overall odds ratio (OR) of 15.3 (p < 0.001) suggests that Greyhounds are at significantly higher risk than other breeds for hookworm positive float findings, and the OR of 14.3 (p < 0.001) suggests significantly higher risk for hookworm antigen positive results. The median time to negative testing event from the Turnbull distribution estimate was in the interval of 1-2 days for other breeds and 71-72 days for Greyhounds. These results provide evidence that anthelmintic resistant A. caninum strains may be having population-level impacts on the frequency and duration of infections in Greyhounds. The findings have broader health implications beyond Greyhounds as MADR A. caninum strains could spread to other breeds and even pet owners.
    Mesh-Begriff(e) Animals ; Dogs ; Dog Diseases/parasitology ; Dog Diseases/diagnosis ; Feces/parasitology ; Retrospective Studies ; Ancylostoma/isolation & purification ; Hookworm Infections/veterinary ; Hookworm Infections/parasitology ; Hookworm Infections/diagnosis ; Immunoassay/veterinary ; Immunoassay/methods ; Ancylostomiasis/veterinary ; Ancylostomiasis/diagnosis ; Ancylostomiasis/parasitology ; Antigens, Helminth/analysis ; Antigens, Helminth/immunology ; Female ; Male
    Sprache Englisch
    Erscheinungsdatum 2024-04-20
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ISSN 2405-9390
    ISSN (online) 2405-9390
    DOI 10.1016/j.vprsr.2024.101026
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Serum Symmetric Dimethylarginine Concentration in Greyhound Pups and Adults.

    Couto, C Guillermo / Murphy, Rachel / Coyne, Michael / Drake, Corie

    Topics in companion animal medicine

    2021  Band 45, Seite(n) 100558

    Abstract: Greyhounds have developed numerous physiologic and hematologic adaptations specific to the breed. Adult Greyhounds have significantly higher serum creatinine (sCr) concentrations than non-Greyhound dogs; this is primarily attributed to their large muscle ...

    Abstract Greyhounds have developed numerous physiologic and hematologic adaptations specific to the breed. Adult Greyhounds have significantly higher serum creatinine (sCr) concentrations than non-Greyhound dogs; this is primarily attributed to their large muscle mass. Adult Greyhounds also have significantly higher symmetric dimethylarginine (SDMA) concentrations than non-Greyhound dogs. In this study we evaluated serum SDMA and sCr concentrations in 48 Greyhound pups from 11 litters, with no exposure to racing, in order to determine if the higher SDMA or sCr concentration in adults is a breed-related trait or is associated with extra-physiological causes (e.g., racing environment, drug administration, etc.). The distribution of SDMA concentration for all the pups (mean: 0.70 µmol/L; 95% CI: 0.70-0.74 µmol/L) was not statistically different from that found in a group of 183 adult Greyhounds; whereas, distribution of sCr concentration in the pups (mean: 76.9 µmol/L; 95% CI: 70.7-83.1 µmol/L) was significantly different than that observed in adult Greyhounds, suggesting that the 2 samples were drawn from different populations. This study provides evidence to support that the higher serum SDMA concentration in Greyhounds is a breed-related trait.
    Mesh-Begriff(e) Animals ; Arginine/analogs & derivatives ; Dogs ; Records/veterinary
    Chemische Substanzen symmetric dimethylarginine (49787G1ULV) ; Arginine (94ZLA3W45F)
    Sprache Englisch
    Erscheinungsdatum 2021-07-08
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1946-9837
    ISSN (online) 1946-9837
    DOI 10.1016/j.tcam.2021.100558
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel: Serum Symmetric Dimethylarginine Concentration in Greyhound Pups and Adults

    Couto, C. Guillermo / Murphy, Rachel / Coyne, Michael / Drake, Corie

    Topics in companion animal medicine. 2021 Nov., v. 45

    2021  

    Abstract: Greyhounds have developed numerous physiologic and hematologic adaptations specific to the breed. Adult Greyhounds have significantly higher serum creatinine (sCr) concentrations than non-Greyhound dogs; this is primarily attributed to their large muscle ...

    Abstract Greyhounds have developed numerous physiologic and hematologic adaptations specific to the breed. Adult Greyhounds have significantly higher serum creatinine (sCr) concentrations than non-Greyhound dogs; this is primarily attributed to their large muscle mass. Adult Greyhounds also have significantly higher symmetric dimethylarginine (SDMA) concentrations than non-Greyhound dogs. In this study we evaluated serum SDMA and sCr concentrations in 48 Greyhound pups from 11 litters, with no exposure to racing, in order to determine if the higher SDMA or sCr concentration in adults is a breed-related trait or is associated with extra-physiological causes (e.g., racing environment, drug administration, etc.). The distribution of SDMA concentration for all the pups (mean: 0.70 µmol/L; 95% CI: 0.70-0.74 µmol/L) was not statistically different from that found in a group of 183 adult Greyhounds; whereas, distribution of sCr concentration in the pups (mean: 76.9 µmol/L; 95% CI: 70.7-83.1 µmol/L) was significantly different than that observed in adult Greyhounds, suggesting that the 2 samples were drawn from different populations. This study provides evidence to support that the higher serum SDMA concentration in Greyhounds is a breed-related trait.
    Schlagwörter Greyhound ; adults ; blood serum ; creatinine ; drugs ; medicine ; muscle tissues ; pets
    Sprache Englisch
    Erscheinungsverlauf 2021-11
    Erscheinungsort Elsevier Inc.
    Dokumenttyp Artikel
    ISSN 1938-9736
    DOI 10.1016/j.tcam.2021.100558
    Datenquelle NAL Katalog (AGRICOLA)

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  5. Artikel ; Online: Effect of packed red blood cell transfusion on thromboelastographic tracings in dogs with naturally occurring anemia.

    Brooks, Aimee C / Cooper, Edward S / Couto, C Guillermo / Guillaumin, Julien

    American journal of veterinary research

    2020  Band 81, Heft 6, Seite(n) 499–505

    Abstract: Objective: To assess the effect of packed RBC (pRBC) transfusion on thromboelastographic (TEG) tracings in dogs with naturally occurring anemia.: Animals: 22 clinically anemic dogs that received a pRBC transfusion.: Procedures: For each dog, a ... ...

    Abstract Objective: To assess the effect of packed RBC (pRBC) transfusion on thromboelastographic (TEG) tracings in dogs with naturally occurring anemia.
    Animals: 22 clinically anemic dogs that received a pRBC transfusion.
    Procedures: For each dog, a blood sample was collected before and within 3 hours after completion of the pRBC transfusion for a CBC, nonactivated TEG analysis, and measurement of blood viscosity. Wilcoxon signed rank tests were used to compare CBC, viscosity, and TEG variables between pretransfusion and posttransfusion blood samples. Multivariable linear regression was used to assess the effects of pretransfusion-posttransfusion changes in Hct, WBC count, and platelet count on changes in TEG variables.
    Results: Median posttransfusion Hct (21%; range, 13% to 34%) was significantly greater than the median pretransfusion Hct (12.5%; range, 7% to 29%). Packed RBC transfusion was associated with a median increase in Hct of 6.2% (range, 1.2% to 13%). Maximum amplitude significantly decreased from 74.9 to 73.8 mm and clot strength significantly decreased from 14,906 to 14,119 dynes/s after pRBC transfusion. Blood viscosity significantly increased, whereas platelet and WBC counts significantly decreased after transfusion. Multivariable linear regression revealed that pretransfusion-posttransfusion changes in Hct, WBC count, and platelet count were not associated with changes in TEG variables.
    Conclusions and clinical relevance: Results indicated that pRBC transfusion had only small effects on the TEG tracings of hemodynamically stable dogs. Therefore, large changes in TEG tracings following pRBC transfusion are unlikely to be the result of the transfusion and should be investigated further.
    Mesh-Begriff(e) Anemia/veterinary ; Animals ; Blood Transfusion/veterinary ; Dog Diseases ; Dogs ; Erythrocyte Transfusion/veterinary ; Hematocrit/veterinary ; Thrombelastography/veterinary
    Sprache Englisch
    Erscheinungsdatum 2020-06-24
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 390796-x
    ISSN 1943-5681 ; 0002-9645
    ISSN (online) 1943-5681
    ISSN 0002-9645
    DOI 10.2460/ajvr.81.6.499
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Improving quality control for in-clinic hematology analyzers: Common myths and opportunities.

    Michael, Helen T / Nabity, Mary B / Couto, C Guillermo / Moritz, Andreas / Harvey, John W / DeNicola, Dennis B / Hammond, Jeremy M

    Veterinary clinical pathology

    2022  Band 51, Heft 3, Seite(n) 302–310

    Mesh-Begriff(e) Animals ; Hematology ; Platelet Count/veterinary ; Quality Control
    Sprache Englisch
    Erscheinungsdatum 2022-09-12
    Erscheinungsland United States
    Dokumenttyp Letter
    ZDB-ID 2114702-4
    ISSN 1939-165X ; 0275-6382
    ISSN (online) 1939-165X
    ISSN 0275-6382
    DOI 10.1111/vcp.13154
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Hyperkalemia during general anesthesia in two Greyhounds.

    Jones, Stacey J / Mama, Khursheed R / Brock, Nancy K / Couto, C Guillermo

    Journal of the American Veterinary Medical Association

    2019  Band 254, Heft 11, Seite(n) 1329–1334

    Abstract: Case description: A 36-kg (79-lb) castrated male Greyhound (dog 1) and a 25-kg (55 lb) spayed female Greyhound (dog 2) underwent general anesthesia for dental care with similar perianesthetic protocols on multiple occasions from 2013 to 2016. Both dogs ... ...

    Abstract Case description: A 36-kg (79-lb) castrated male Greyhound (dog 1) and a 25-kg (55 lb) spayed female Greyhound (dog 2) underwent general anesthesia for dental care with similar perianesthetic protocols on multiple occasions from 2013 to 2016. Both dogs had periodontal disease but were otherwise deemed healthy. Both dogs developed clinically relevant hyperkalemia, with signs including loss of P waves on ECG tracings, during multiple anesthetic events.
    Clinical findings: Dog 1 developed hyperkalemia during 2 of 2 anesthetic events, with ECG changes noted during the first event. Dog 2 developed hyperkalemia during 3 of 4 anesthetic events, with ECG changes identified during the second and third events. Serum potassium concentration for both dogs was within the reference range prior to and between anesthetic events. No underlying etiopathogenesis for hyperkalemia was identified for either dog.
    Treatment and outcome: In each hyperkalemic event, the clinician stopped the dental procedure and continued to provide supportive care and monitoring while the dog recovered from anesthesia. The ECG changes resolved, and serum potassium concentration returned to the reference range rapidly after inhalant anesthetic administration was discontinued. The dogs were discharged from the hospital without further complications.
    Clinical relevance: Hyperkalemia in anesthetized Greyhounds resulted in serious cardiac conduction abnormalities, which could be potentially fatal if not recognized and promptly treated. Further investigation into the etiopathogenesis, prevention and treatment strategies, and genetic or familial components of this condition is indicated.
    Mesh-Begriff(e) Anesthesia, General/veterinary ; Animals ; Dog Diseases/diagnosis ; Dogs ; Female ; Hyperkalemia/diagnosis ; Hyperkalemia/veterinary ; Male
    Sprache Englisch
    Erscheinungsdatum 2019-05-08
    Erscheinungsland United States
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    DOI 10.2460/javma.254.11.1329
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Buch: Small animal internal medicine

    Nelson, Richard W / Couto, C. Guillermo

    2014  

    Verfasserangabe [edited by] Richard W. Nelson, C. Guillermo Couto
    Mesh-Begriff(e) Dog Diseases ; Cat Diseases ; Veterinary Medicine/methods
    Sprache Englisch
    Umfang xxix, 1473 pages :, illustrations, portraits
    Ausgabenhinweis Fifth edition.
    Dokumenttyp Buch
    ISBN 9780323086820 ; 0323086829
    Datenquelle Katalog der US National Library of Medicine (NLM)

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  9. Buch: Small animal internal medicine

    Couto, C. Guillermo / Nelson, Richard William

    2014  

    Verfasserangabe [edited by] Richard W. Nelson, C. Guillermo Couto
    Mesh-Begriff(e) Cat Diseases ; Dog Diseases ; Veterinary Medicine/methods
    Schlagwörter Cats/Diseases ; Dogs/Diseases ; Veterinary internal medicine
    Sprache Englisch
    Umfang XXIX, 1473 S., Ill., graph. Darst.
    Ausgabenhinweis Fifth edition
    Verlag Elsevier/Mosby
    Erscheinungsort St. Louis, Mo
    Dokumenttyp Buch
    Anmerkung Includes bibliographical references and index
    ISBN 9780323086820 ; 0323086829
    Datenquelle Bibliothek der Tierärztlichen Hochschule Hannover

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  10. Buch ; Online: Small animal internal medicine

    Couto, C. Guillermo / Nelson, Richard William

    2014  

    Verfasserangabe [edited by] Richard W. Nelson, DVM, DACVIM (Internal medicine), C. Guillermo Couto, DVM, DACVIM (Internal medicine and oncology)
    Mesh-Begriff(e) Cat Diseases ; Dog Diseases ; Veterinary Medicine/methods
    Schlagwörter Cats/Diseases ; Dogs/Diseases ; Veterinary internal medicine
    Sprache Englisch
    Umfang Online-Ressource (xxix, 1473 pages), color illustrations
    Ausgabenhinweis Fifth edition
    Verlag Elsevier
    Erscheinungsort St. Louis, Mo
    Dokumenttyp Buch ; Online
    Anmerkung Includes bibliographical references and index
    ISBN 0323086829 ; 0323243002 ; 9780323086820 ; 9780323243001
    Datenquelle Bibliothek der Tierärztlichen Hochschule Hannover

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