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  1. Article: Synthesis and Biological Evaluation of Enantiomerically Pure (

    Korff, Marvin / Chaudhary, Ahmad / Li, Yinlong / Zhou, Xin / Zhao, Chunyu / Rong, Jian / Chen, Jiahui / Xiao, Zhiwei / Elghazawy, Nehal H / Sippl, Wolfgang / Davenport, April T / Daunais, James B / Wang, Lu / Abate, Carmen / Ahmed, Hazem / Crowe, Ron / Liang, Steven H / Ametamey, Simon M / Wünsch, Bernhard /
    Haider, Ahmed

    Research square

    2023  

    Abstract: GluN2B subunit- ... ...

    Abstract GluN2B subunit-containing
    Language English
    Publishing date 2023-01-27
    Publishing country United States
    Document type Preprint
    DOI 10.21203/rs.3.rs-2516002/v1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Evaluation of [

    Haider, Ahmed / Wang, Lu / Gobbi, Luca / Li, Yinlong / Chaudhary, Ahmad / Zhou, Xin / Chen, Jiahui / Zhao, Chunyu / Rong, Jian / Xiao, Zhiwei / Hou, Lu / Elghazawy, Nehal H / Sippl, Wolfgang / Davenport, April T / Daunais, James B / Ahmed, Hazem / Crowe, Ron / Honer, Michael / Rominger, Axel /
    Grether, Uwe / Liang, Steven H / Ametamey, Simon M

    ACS chemical neuroscience

    2023  Volume 14, Issue 20, Page(s) 3752–3760

    Abstract: The cannabinoid type 2 receptor (CB2) has been implicated in a variety of central and peripheral inflammatory diseases, prompting significant interest in the development of CB2-targeted diagnostic and therapeutic agents. A validated positron emission ... ...

    Abstract The cannabinoid type 2 receptor (CB2) has been implicated in a variety of central and peripheral inflammatory diseases, prompting significant interest in the development of CB2-targeted diagnostic and therapeutic agents. A validated positron emission tomography (PET) radioligand for imaging CB2 in the living human brain as well as in peripheral tissues is currently lacking. As part of our research program, we have recently identified the trisubstituted pyridine, [
    MeSH term(s) Animals ; Humans ; Radiopharmaceuticals/metabolism ; Positron-Emission Tomography/methods ; Ligands ; Brain/diagnostic imaging ; Brain/metabolism ; Primates/metabolism ; Receptor, Cannabinoid, CB2/metabolism ; Fluorine Radioisotopes/metabolism ; Mammals/metabolism
    Chemical Substances Radiopharmaceuticals ; Ligands ; Receptor, Cannabinoid, CB2 ; Fluorine Radioisotopes
    Language English
    Publishing date 2023-10-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1948-7193
    ISSN (online) 1948-7193
    DOI 10.1021/acschemneuro.3c00222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Synthesis and Biological Evaluation of Enantiomerically Pure (

    Korff, Marvin / Chaudhary, Ahmad / Li, Yinlong / Zhou, Xin / Zhao, Chunyu / Rong, Jian / Chen, Jiahui / Xiao, Zhiwei / Elghazawy, Nehal H / Sippl, Wolfgang / Davenport, April T / Daunais, James B / Wang, Lu / Abate, Carmen / Ahmed, Hazem / Crowe, Ron / Schmidt, Thomas J / Liang, Steven H / Ametamey, Simon M /
    Wünsch, Bernhard / Haider, Ahmed

    Journal of medicinal chemistry

    2023  Volume 66, Issue 23, Page(s) 16018–16031

    Abstract: GluN2B subunit- ... ...

    Abstract GluN2B subunit-containing
    MeSH term(s) Animals ; Humans ; Receptors, N-Methyl-D-Aspartate/metabolism ; Positron-Emission Tomography/methods ; Brain/diagnostic imaging ; Brain/metabolism ; Fluorine Radioisotopes
    Chemical Substances Fluorine-18 (GZ5I74KB8G) ; Receptors, N-Methyl-D-Aspartate ; Fluorine Radioisotopes
    Language English
    Publishing date 2023-11-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 218133-2
    ISSN 1520-4804 ; 0022-2623
    ISSN (online) 1520-4804
    ISSN 0022-2623
    DOI 10.1021/acs.jmedchem.3c01441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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