Artikel ; Online: IRE-1 endoribonuclease activity declines early in
2022 Band 3, Seite(n) 1044556
Abstract: The proteome of a cell helps to define its functional specialization. Most proteins must be translated and properly folded to ensure their biological function, but with aging, animals lose their ability to maintain a correctly folded proteome. This leads ...
Abstract | The proteome of a cell helps to define its functional specialization. Most proteins must be translated and properly folded to ensure their biological function, but with aging, animals lose their ability to maintain a correctly folded proteome. This leads to the accumulation of protein aggregates, decreased stress resistance, and the onset of age-related disorders. The unfolded protein response of the endoplasmic reticulum (UPR |
---|---|
Sprache | Englisch |
Erscheinungsdatum | 2022-10-28 |
Erscheinungsland | Switzerland |
Dokumenttyp | Journal Article |
ZDB-ID | 3076785-4 |
ISSN | 2673-6217 ; 2673-6217 |
ISSN (online) | 2673-6217 |
ISSN | 2673-6217 |
DOI | 10.3389/fragi.2022.1044556 |
Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
Zusatzmaterialien
Kategorien
Über subito bestellen
Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.