LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Suchergebnis

Treffer 1 - 3 von insgesamt 3

Suchoptionen

  1. Buch ; Audio / Video ; Online: Production of beneficial insects in the Ramacca Biofactory for Biocontrol in citrus fruits (BIOFRUITNET Video)

    Alföldi, Thomas / Verrastro, Vincenzo / D'Angelo, Dario / Calcaterra, Salvatore

    2023  

    Abstract: The Ramacca Biofactory in Sicily breeds beneficial insects for citrus farming. This video presents some of the insects that are produced: The first is a parasitoid called Aphytis melinus. The second is a predator, a ladybird. It is called Cryptolaemus ... ...

    Abstract The Ramacca Biofactory in Sicily breeds beneficial insects for citrus farming. This video presents some of the insects that are produced: The first is a parasitoid called Aphytis melinus. The second is a predator, a ladybird. It is called Cryptolaemus montrouzieri. We will also look at the two species on which these two useful insects are bred (Aspidiotus nerii and Planococcus citri).
    Schlagwörter Biodiversity and ecosystem services ; Fruit and berries ; Crop health ; quality ; protection
    Sprache Englisch
    Erscheinungsland dk
    Dokumenttyp Buch ; Audio / Video ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  2. Buch ; Online: Production of beneficial insects in the Ramacca Biofactory for Biocontrol in citrus fruits (BIOFRUITNET Video)

    Alföldi, Thomas / Verrastro, Vincenzo / D'Angelo, Dario / Strano, Antonio / Calcaterra, Salvatore

    2023  

    Abstract: The Ramacca Biofactory in Sicily breeds beneficial insects for citrus farming. This video presents some of the insects that are produced: The first is a parasitoid called Aphytis melinus. The second is a predator, a ladybird. It is called Cryptolaemus ... ...

    Abstract The Ramacca Biofactory in Sicily breeds beneficial insects for citrus farming. This video presents some of the insects that are produced: The first is a parasitoid called Aphytis melinus. The second is a predator, a ladybird. It is called Cryptolaemus montrouzieri. We will also look at the two species on which these two useful insects are bred (Aspidiotus nerii and Planococcus citri).
    Schlagwörter Biodiversity and ecosystem services ; Fruit and berries ; Crop health ; quality ; protection
    Sprache Italienisch
    Erscheinungsland dk
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

    Volltext online

    Zusatzmaterialien

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

  3. Artikel ; Online: Oxidative Stress Mediates the Antiproliferative Effects of Nelfinavir in Breast Cancer Cells.

    Soprano, Maria / Sorriento, Daniela / Rusciano, Maria Rosaria / Maione, Angela Serena / Limite, Gennaro / Forestieri, Pietro / D'Angelo, Dario / D'Alessio, Matteo / Campiglia, Pietro / Formisano, Pietro / Iaccarino, Guido / Bianco, Roberto / Illario, Maddalena

    PloS one

    2016  Band 11, Heft 6, Seite(n) e0155970

    Abstract: The discovery of the anti-proliferative activity of nelfinavir in HIV-free models has encouraged its investigation as anticancer drug. Although the molecular mechanism by which nelfinavir exerts antitumor activity is still unknown, its effects have been ... ...

    Abstract The discovery of the anti-proliferative activity of nelfinavir in HIV-free models has encouraged its investigation as anticancer drug. Although the molecular mechanism by which nelfinavir exerts antitumor activity is still unknown, its effects have been related to Akt inhibition. Here we tested the effects of nelfinavir on cell proliferation, viability and death in two human breast cancer cell lines and in human normal primary breast cells. To identify the mechanism of action of nelfinavir in breast cancer, we evaluated the involvement of the Akt pathway as well as the effects of nelfinavir on reactive oxygen species (ROS) production and ROS-related enzymes activities. Nelfinavir reduced breast cancer cell viability by inducing apoptosis and necrosis, without affecting primary normal breast cells. The antitumor activity of nelfinavir was related to alterations of the cell redox state, coupled with an increase of intracellular ROS production limited to cancer cells. Nelfinavir treated tumor cells also displayed a downregulation of the Akt pathway due to disruption of the Akt-HSP90 complex, and subsequent degradation of Akt. These effects resulted to be ROS dependent, suggesting that ROS production is the primary step of nelfinavir anticancer activity. The analysis of ROS-producers and ROS-detoxifying enzymes revealed that nelfinavir-mediated ROS production was strictly linked to flavoenzymes activation. We demonstrated that ROS enhancement represents the main molecular mechanism required to induce cell death by nelfinavir in breast cancer cells, thus supporting the development of new and more potent oxidizing molecules for breast cancer therapy.
    Mesh-Begriff(e) Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Breast Neoplasms/drug therapy ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Proliferation/drug effects ; Female ; HIV Protease Inhibitors/pharmacology ; Humans ; Nelfinavir/pharmacology ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism ; Tumor Cells, Cultured
    Chemische Substanzen Antineoplastic Agents ; HIV Protease Inhibitors ; Reactive Oxygen Species ; Nelfinavir (HO3OGH5D7I)
    Sprache Englisch
    Erscheinungsdatum 2016
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0155970
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Zum Seitenanfang