Artikel ; Online: Neutropenia febril posquimioterapia. Estancia hospitalaria y experiencia en nuestro medio.
2019 Band 92, Heft 3, Seite(n) 141–146
Abstract: Introduction: Infections are significant cause of morbidity and mortality in cancer patients (mortality is estimated at around 3%). Febrile neutropenia often leads to the hospitalisation of cancer patients, increasing the risk of nosocomial infection, ... ...
| Titelübersetzung | Post chemoterapy febrile neutropenia. Length of stay and experience in our population. |
|---|---|
| Abstract | Introduction: Infections are significant cause of morbidity and mortality in cancer patients (mortality is estimated at around 3%). Febrile neutropenia often leads to the hospitalisation of cancer patients, increasing the risk of nosocomial infection, as well as health costs due to the hospital admission. Methods: An ambispective (01 July 2015 - 12 July 2018) observational study was conducted on all episodes of chemotherapy-induced febrile neutropenia in a paediatric population. A record was made of age, gender, weight percentile (WHO), length of hospital stay (days), temperature (oC), microbial isolation, infectious source, antibiotic or antifungal prophylaxis, haemoglobin (g/dl), platelets (/mm Results: The study included 69 patients, and 101 episodes were recorded. The mean stay was 7.43 days (median 6 days). Microbial isolation was found in 44.6% of the episodes, with no infectious source identified in 36% of them. An inverse correlation was found between haemoglobin, platelets, and lymphocytes on admission and the hospital stay (-0.356: P=.001, -0.216: P=.042, and -0.216: P=.042, respectively). The mean stay was greater if there was a CRP>90mg/L (10.94 vs. 6.66 days, P=.017), if PCT>1ng/ml (16.50 vs. 6.77 days, P=.0002), if ≤ 100 neutrophils (8.27 vs. 5.04 days P=.039) on admission, and if there was microbe isolation (9.54 vs. 5.78 days P=.006). Conclusion: The relationship between haemoglobin, platelets, and lymphocytes on admission and the mean stay is inversely proportional. In addition, those patients with ≤100 neutrophils, CRP>90mg/L, and PCT>1ng/ml on admission had a longer hospital stay. |
| Mesh-Begriff(e) | Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Child ; Febrile Neutropenia/chemically induced ; Febrile Neutropenia/epidemiology ; Febrile Neutropenia/therapy ; Female ; Humans ; Infections/epidemiology ; Infections/microbiology ; Length of Stay ; Male ; Neoplasms/drug therapy ; Prospective Studies ; Retrospective Studies ; Risk Factors |
| Chemische Substanzen | Antineoplastic Agents |
| Sprache | Spanisch |
| Erscheinungsdatum | 2019-06-22 |
| Erscheinungsland | Netherlands |
| Dokumenttyp | Journal Article ; Observational Study |
| ZDB-ID | 2830901-7 |
| ISSN | 2341-2879 ; 2341-2879 |
| ISSN (online) | 2341-2879 |
| ISSN | 2341-2879 |
| DOI | 10.1016/j.anpedi.2019.05.008 |
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
Zusatzmaterialien
Kategorien
Über subito bestellen
Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.