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  1. Artikel ; Online: The application of transient elastography for early diagnosis of pregnancy-related complications.

    Hassam, Khawaja / Raza, Muhammad Asad / Dad Ullah, Mati Ullah

    American journal of obstetrics and gynecology

    2023  Band 230, Heft 1, Seite(n) 104–105

    Mesh-Begriff(e) Female ; Pregnancy ; Humans ; Elasticity Imaging Techniques ; Liver ; ROC Curve ; Early Diagnosis
    Sprache Englisch
    Erscheinungsdatum 2023-08-25
    Erscheinungsland United States
    Dokumenttyp Letter
    ZDB-ID 80016-8
    ISSN 1097-6868 ; 0002-9378
    ISSN (online) 1097-6868
    ISSN 0002-9378
    DOI 10.1016/j.ajog.2023.08.021
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Artikel: Novel Therapies of Hepatitis B and D

    Khan, Iman Waheed / Dad Ullah, Mati Ullah / Choudhry, Mina / Ali, Mukarram Jamat / Ali, Muhammad Ashar / Lam, Sam L. K. / Shah, Pir Ahmad / Kaur, Satinder Pal / Lau, Daryl T. Y.

    Microorganisms. 2021 Dec. 17, v. 9, no. 12

    2021  

    Abstract: Hepatitis B virus (HBV) infection is a global public health issue and is a major cause of cirrhosis and hepatocellular carcinoma (HCC). Hepatitis D virus (HDV) requires the hepatitis B surface antigen (HBsAg) to replicate. The eradication of HBV, ... ...

    Abstract Hepatitis B virus (HBV) infection is a global public health issue and is a major cause of cirrhosis and hepatocellular carcinoma (HCC). Hepatitis D virus (HDV) requires the hepatitis B surface antigen (HBsAg) to replicate. The eradication of HBV, therefore, can also cure HDV. The current therapies for chronic hepatitis B and D are suboptimal and cannot definitely cure the viruses. In order to achieve functional or complete cure of these infections, novel therapeutic agents that target the various sites of the viral replicative cycle are necessary. Furthermore, novel immunomodulatory agents are also essential to achieve viral clearance. Many of these new promising compounds such as entry inhibitors, covalently closed circular DNA (cccDNA) inhibitors, small interfering RNAs (siRNAs), capsid assembly modulators and nucleic acid polymers are in various stages of clinical developments. In this review article, we provided a comprehensive overview of the structure and lifecycle of HBV, the limitations of the current therapies and a summary of the novel therapeutic agents for both HDV and HBV infection.
    Schlagwörter Hepatitis B virus ; capsid ; chemical bonding ; chronic hepatitis B ; circular DNA ; hepatitis B antigens ; hepatoma ; public health ; therapeutics ; viruses
    Sprache Englisch
    Erscheinungsverlauf 2021-1217
    Erscheinungsort Multidisciplinary Digital Publishing Institute
    Dokumenttyp Artikel
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms9122607
    Datenquelle NAL Katalog (AGRICOLA)

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  3. Artikel: Novel Therapies of Hepatitis B and D.

    Khan, Iman Waheed / Dad Ullah, Mati Ullah / Choudhry, Mina / Ali, Mukarram Jamat / Ali, Muhammad Ashar / Lam, Sam L K / Shah, Pir Ahmad / Kaur, Satinder Pal / Lau, Daryl T Y

    Microorganisms

    2021  Band 9, Heft 12

    Abstract: Hepatitis B virus (HBV) infection is a global public health issue and is a major cause of cirrhosis and hepatocellular carcinoma (HCC). Hepatitis D virus (HDV) requires the hepatitis B surface antigen (HBsAg) to replicate. The eradication of HBV, ... ...

    Abstract Hepatitis B virus (HBV) infection is a global public health issue and is a major cause of cirrhosis and hepatocellular carcinoma (HCC). Hepatitis D virus (HDV) requires the hepatitis B surface antigen (HBsAg) to replicate. The eradication of HBV, therefore, can also cure HDV. The current therapies for chronic hepatitis B and D are suboptimal and cannot definitely cure the viruses. In order to achieve functional or complete cure of these infections, novel therapeutic agents that target the various sites of the viral replicative cycle are necessary. Furthermore, novel immunomodulatory agents are also essential to achieve viral clearance. Many of these new promising compounds such as entry inhibitors, covalently closed circular DNA (cccDNA) inhibitors, small interfering RNAs (siRNAs), capsid assembly modulators and nucleic acid polymers are in various stages of clinical developments. In this review article, we provided a comprehensive overview of the structure and lifecycle of HBV, the limitations of the current therapies and a summary of the novel therapeutic agents for both HDV and HBV infection.
    Sprache Englisch
    Erscheinungsdatum 2021-12-17
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms9122607
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

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