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Artikel ; Online: The Anticonvulsant Lamotrigine Reduces Bout-Like Alcohol Drinking in Rats.

Poceviciute, Ieva / Buisas, Rokas / Danelius, Tadas / Dulinskas, Redas / Ruksenas, Osvaldas / Vengeliene, Valentina

Alcohol and alcoholism (Oxford, Oxfordshire)

2021  Band 57, Heft 2, Seite(n) 242–245

Abstract: We used an optical lickometer system to study drinking microstructure and effect of lamotrigine in voluntary alcohol-drinking rats. We showed that, similar to humans, animals differ by their drinking microstructure where some consume alcohol exclusively ... ...

Abstract We used an optical lickometer system to study drinking microstructure and effect of lamotrigine in voluntary alcohol-drinking rats. We showed that, similar to humans, animals differ by their drinking microstructure where some consume alcohol exclusively in a bout-like patterns. The study suggests that anticonvulsants, such as lamotrigine, may be one treatment strategy specifically affecting this type of drinking.
Mesh-Begriff(e) Alcohol Drinking/drug therapy ; Animals ; Anticonvulsants/pharmacology ; Anticonvulsants/therapeutic use ; Ethanol ; Lamotrigine ; Rats
Chemische Substanzen Anticonvulsants ; Ethanol (3K9958V90M) ; Lamotrigine (U3H27498KS)
Sprache Englisch
Erscheinungsdatum 2021-10-30
Erscheinungsland England
Dokumenttyp Journal Article
ZDB-ID 604956-4
ISSN 1464-3502 ; 0309-1635 ; 0735-0414
ISSN (online) 1464-3502
ISSN 0309-1635 ; 0735-0414
DOI 10.1093/alcalc/agab073
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