Artikel ; Online: Genome Replication Is Associated With Release of Immunogenic DNA Waste.
2022 Band 13, Seite(n) 880413
Abstract: Innate DNA sensors detect foreign and endogenous DNA to induce responses to infection and cellular stress or damage. Inappropriate activation by self-DNA triggers severe autoinflammatory conditions, including Aicardi-Goutières syndrome (AGS) that can be ... ...
| Abstract | Innate DNA sensors detect foreign and endogenous DNA to induce responses to infection and cellular stress or damage. Inappropriate activation by self-DNA triggers severe autoinflammatory conditions, including Aicardi-Goutières syndrome (AGS) that can be caused by defects of the cytosolic DNase 3'repair exonuclease 1 (TREX1). |
|---|---|
| Mesh-Begriff(e) | Animals ; Autoimmune Diseases of the Nervous System ; Mice ; Nervous System Malformations/pathology ; Nucleotidyltransferases/metabolism ; Retroelements ; Virus Replication |
| Chemische Substanzen | Retroelements ; Nucleotidyltransferases (EC 2.7.7.-) |
| Sprache | Englisch |
| Erscheinungsdatum | 2022-05-11 |
| Erscheinungsland | Switzerland |
| Dokumenttyp | Journal Article ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 2606827-8 |
| ISSN | 1664-3224 ; 1664-3224 |
| ISSN (online) | 1664-3224 |
| ISSN | 1664-3224 |
| DOI | 10.3389/fimmu.2022.880413 |
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
Zusatzmaterialien
Kategorien
Über subito bestellen
Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.