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  1. Artikel ; Online: A Comparison of Risk Estimates for the Effect of Short-Term Exposure to PM, NO2 and CO on Cardiovascular Hospitalizations and Emergency Department Visits

    Lindsay Wichers Stanek / Thomas J. Luben / Genee Smith / Thomas C. Long / Dennis Kotchmar / Doug Johns / Allen Davis / Mary Ross / Barbara Buckley / David Svendsgaard / Ellen Kirrane

    Atmosphere, Vol 2, Iss 4, Pp 688-

    Effect Size Modeling of Study Findings

    2011  Band 701

    Abstract: Although particulate matter (PM), nitrogen dioxide (NO2) and carbon monoxide (CO) typically exist as part of a complex air pollution mixture, the evidence linking these pollutants to health effects is evaluated separately in the scientific and policy ... ...

    Abstract Although particulate matter (PM), nitrogen dioxide (NO2) and carbon monoxide (CO) typically exist as part of a complex air pollution mixture, the evidence linking these pollutants to health effects is evaluated separately in the scientific and policy reviews of the National Ambient Air Quality Standards (NAAQS). The objective of this analysis was to use meta-regression methods to model effect estimates for several individual yet correlated NAAQS pollutants in an effort to identify factors that explain differences in the effect sizes across studies and across pollutants. We expected that our consideration of the evidence for several correlated pollutants in parallel could lead to insights regarding exposure to the pollutant mixture. We focused on studies of hospital admissions for congestive heart failure (CHF) and ischemic heart disease (IHD), which have played an important role in the evaluation of the scientific evidence communicated in the PM, NO2, and CO Integrated Science Assessments (ISAs). Of the studies evaluated, 11 CHF studies and 21 IHD studies met our inclusion requirements. The size of the risk estimates was explained by factors related to the pollution mixture, study methods, and monitoring network characteristics. Our findings suggest that additional analyses focusing on understanding differences in effect sizes across geographic areas with different pollution mixtures and monitor network designs may improve our understanding of the independent and combined effects of correlated pollutants.
    Schlagwörter hospital admissions ; air pollution ; PM ; NO2 ; CO ; Meteorology. Climatology ; QC851-999 ; Physics ; QC1-999 ; Science ; Q ; DOAJ:Meteorology and Climatology ; DOAJ:Earth and Environmental Sciences
    Thema/Rubrik (Code) 333
    Sprache Englisch
    Erscheinungsdatum 2011-12-01T00:00:00Z
    Verlag MDPI AG
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel: A Comparison of Risk Estimates for the Effect of Short-Term Exposure to PM, NO2 and CO on Cardiovascular Hospitalizations and Emergency Department Visits: Effect Size Modeling of Study Findings

    Ellen Kirrane / David Svendsgaard / Mary Ross / Barbara Buckley / Allen Davis / Doug Johns / Dennis Kotchmar / Thomas C. Long / Thomas J. Luben / Genee Smith / Lindsay Wichers Stanek

    Atmosphere

    Heft (4)

    Abstract: Although particulate matter (PM), nitrogen dioxide (NO2) and carbon monoxide (CO) typically exist as part of a complex air pollution mixture, the evidence linking these pollutants to health effects is evaluated separately in the scientific and policy ... ...

    Abstract Although particulate matter (PM), nitrogen dioxide (NO2) and carbon monoxide (CO) typically exist as part of a complex air pollution mixture, the evidence linking these pollutants to health effects is evaluated separately in the scientific and policy reviews of the National Ambient Air Quality Standards (NAAQS). The objective of this analysis was to use meta-regression methods to model effect estimates for several individual yet correlated NAAQS pollutants in an effort to identify factors that explain differences in the effect sizes across studies and across pollutants. We expected that our consideration of the evidence for several correlated pollutants in parallel could lead to insights regarding exposure to the pollutant mixture. We focused on studies of hospital admissions for congestive heart failure (CHF) and ischemic heart disease (IHD), which have played an important role in the evaluation of the scientific evidence communicated in the PM, NO2, and CO Integrated Science Assessments (ISAs). Of the studies evaluated, 11 CHF studies and 21 IHD studies met our inclusion requirements. The size of the risk estimates was explained by factors related to the pollution mixture, study methods, and monitoring network characteristics. Our findings suggest that additional analyses focusing on understanding differences in effect sizes across geographic areas with different pollution mixtures and monitor network designs may improve our understanding of the independent and combined effects of correlated pollutants.
    Sprache Englisch
    Dokumenttyp Artikel
    Datenquelle AGRIS - International Information System for the Agricultural Sciences and Technology

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