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  1. Artikel ; Online: The Palliative Care Needs of Patients with Multiple Sclerosis, Parkinson's Related Diseases, and Motor Neurone Disease: A Secondary Analysis of the OPTCARE Neuro Trial Data.

    Doherty, Mairéad / Chukwusa, Emeka / McQuillan, Regina / Cranfield, Faith / Gao, Wei

    Journal of palliative medicine

    2024  Band 27, Heft 5, Seite(n) 622–629

    Abstract: Background: ...

    Abstract Background:
    Mesh-Begriff(e) Humans ; Male ; Female ; Middle Aged ; Multiple Sclerosis/psychology ; Multiple Sclerosis/therapy ; Palliative Care ; Cross-Sectional Studies ; Motor Neuron Disease/psychology ; Motor Neuron Disease/therapy ; United Kingdom ; Parkinson Disease/psychology ; Parkinson Disease/therapy ; Aged ; Adult
    Sprache Englisch
    Erscheinungsdatum 2024-04-09
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Multicenter Study
    ZDB-ID 1427361-5
    ISSN 1557-7740 ; 1096-6218
    ISSN (online) 1557-7740
    ISSN 1096-6218
    DOI 10.1089/jpm.2023.0437
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Opioid toxicity after oxycodone/naloxone to oxycodone conversion: case series.

    Doherty, Mairead / Featherstone, Hannah Joan / McAleer, Clare / Webb, Chloe / O'Reilly, Maeve / Twomey, Marie / McQuillan, Regina

    BMJ supportive & palliative care

    2024  

    Abstract: Combination preparations of oxycodone/naloxone are marketed to aid in the management of opioid induced bowel dysfunction, with caution advised in prescribing in cases of liver dysfunction.This case series demonstrates four cases of patients with normal ... ...

    Abstract Combination preparations of oxycodone/naloxone are marketed to aid in the management of opioid induced bowel dysfunction, with caution advised in prescribing in cases of liver dysfunction.This case series demonstrates four cases of patients with normal liver function tests who developed significant opioid toxicity on conversion from combination oxycodone/naloxone to oxycodone at equivalent doses, necessitating significant dose reduction.In each case, a cause for intra-hepatic shunting such as cirrhosis, porto-systemic collaterals or thrombosis were identified, highlighting these as cautionary features when prescribing combination preparations of oxycodone/naloxone and the possible need for dose reduction if converting to oxycodone.
    Sprache Englisch
    Erscheinungsdatum 2024-02-26
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2045-4368
    ISSN (online) 2045-4368
    DOI 10.1136/spcare-2024-004796
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Is Inpatient Hospice Care Clinically Effective? Using Phase of Illness to Evaluate Care Outcomes for Patients Admitted to a Specialist Palliative Care Unit in Ireland.

    Lucey, Michael / O'Reilly, Martina / Currow, David / Eagar, Kathy / Walsh, Declan / Conroy, Marian / Twomey, Feargal / O'Reilly, Val / Doherty, Mairéad / Coffey, Siobhain / Sheridan, John / Moran, Sue

    Journal of palliative medicine

    2019  Band 23, Heft 4, Seite(n) 535–541

    Abstract: Background: ...

    Abstract Background:
    Mesh-Begriff(e) Hospice Care ; Hospitalization ; Humans ; Inpatients ; Ireland ; Palliative Care
    Sprache Englisch
    Erscheinungsdatum 2019-12-19
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1427361-5
    ISSN 1557-7740 ; 1096-6218
    ISSN (online) 1557-7740
    ISSN 1096-6218
    DOI 10.1089/jpm.2019.0295
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Ia diastolic dysfunction: an echocardiographic grade.

    Pandit, Anil / Mookadam, Farouk / Hakim, Fayaz A / Mulroy, Eoin / Saadiq, Rayya / Doherty, Mairead / Cha, Stephen / Seward, James / Wilansky, Susan

    Echocardiography (Mount Kisco, N.Y.)

    2015  Band 32, Heft 1, Seite(n) 56–63

    Abstract: Objective: To demonstrate that a distinct group of patients with Grade Ia diastolic dysfunction who do not conform to present ASE/ESE diastolic grading exists.: Method and results: Echocardiographic and demographic data of the Grade Ia diastolic ... ...

    Abstract Objective: To demonstrate that a distinct group of patients with Grade Ia diastolic dysfunction who do not conform to present ASE/ESE diastolic grading exists.
    Method and results: Echocardiographic and demographic data of the Grade Ia diastolic dysfunction were extracted and compared with that of Grades I and II in 515 patients. The mean of age of the cohort was 75 ± 9 years and body mass index did not differ significantly between the 3 groups (P = 0.45). Measurements of left atrial volume index (28.58 ± 7 mL/m(2) in I, 33 ± 10 mL/m(2) in Ia, and 39 ± 12 mL/m(2) in II P < 0.001), isovolumic relaxation time (IVRT) (100 ± 17 msec in I, 103 ± 21 msec in Ia, and 79 ± 15 msec in II P < 0.001), deceleration time (248 ± 52 msec in I, 263 ± 58 msec in Ia, and 217 ± 57 msec in II P < 0.001), medial E/e' (10 ± 3 in I, 18 ± 5.00 in Ia, and 22 ± 8 in II), and lateral E/e' (8 ± 3 in I, 15 ± 6 in Ia, and 18 ± 9 in II P < 0.001) were significantly different in grade Ia compared with I and II. These findings remained significant even after adjusting for age, gender, diabetes, and smoking.
    Conclusion: Patients with echocardiographic characteristics of relaxation abnormality (E/A ratio of <0.8) and elevated filling pressures (septal E/e' ≥15, lateral E/e' ≥12, average E/e' ≥13) should be graded as a separate Grade Ia group.
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Echocardiography/methods ; Female ; Humans ; Image Interpretation, Computer-Assisted/methods ; Male ; Middle Aged ; Reproducibility of Results ; Sensitivity and Specificity ; Ventricular Dysfunction, Left/classification ; Ventricular Dysfunction, Left/diagnostic imaging ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2015-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 843645-9
    ISSN 1540-8175 ; 0742-2822
    ISSN (online) 1540-8175
    ISSN 0742-2822
    DOI 10.1111/echo.12600
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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