LIVIVO - Das Suchportal für Lebenswissenschaften

switch to English language
Erweiterte Suche

Suchergebnis

Treffer 1 - 3 von insgesamt 3

Suchoptionen

  1. Artikel ; Online: Hypertonic saline nasal irrigation and gargling should be considered as a treatment option for COVID-19.

    Ramalingam, Sandeep / Graham, Catriona / Dove, Jenny / Morrice, Lynn / Sheikh, Aziz

    Journal of global health

    2020  Band 10, Heft 1, Seite(n) 10332

    Mesh-Begriff(e) Administration, Intranasal ; Betacoronavirus ; Coronavirus/drug effects ; Coronavirus Infections/drug therapy ; Coronavirus Infections/epidemiology ; Humans ; Nasal Cavity/virology ; Nasal Lavage ; Pandemics ; Pharynx/virology ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/epidemiology ; Randomized Controlled Trials as Topic ; Saline Solution, Hypertonic/administration & dosage ; Saline Solution, Hypertonic/pharmacology ; Saline Solution, Hypertonic/therapeutic use ; Therapeutic Irrigation/methods
    Chemische Substanzen Saline Solution, Hypertonic
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2020-05-11
    Erscheinungsland Scotland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2741629-X
    ISSN 2047-2986 ; 2047-2978
    ISSN (online) 2047-2986
    ISSN 2047-2978
    DOI 10.7189/jogh.10.010332
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  2. Artikel ; Online: A pilot, open labelled, randomised controlled trial of hypertonic saline nasal irrigation and gargling for the common cold.

    Ramalingam, Sandeep / Graham, Catriona / Dove, Jenny / Morrice, Lynn / Sheikh, Aziz

    Scientific reports

    2019  Band 9, Heft 1, Seite(n) 1015

    Abstract: There are no antivirals to treat viral upper respiratory tract infection (URTI). Since numerous viruses cause URTI, antiviral therapy is impractical. As we have evidence of chloride-ion dependent innate antiviral response in epithelial cells, we ... ...

    Abstract There are no antivirals to treat viral upper respiratory tract infection (URTI). Since numerous viruses cause URTI, antiviral therapy is impractical. As we have evidence of chloride-ion dependent innate antiviral response in epithelial cells, we conducted a pilot, non-blinded, randomised controlled trial of hypertonic saline nasal irrigation and gargling (HSNIG) vs standard care on healthy adults within 48 hours of URTI onset to assess recruitment (primary outcome). Acceptability, symptom duration and viral shedding were secondary outcomes. Participants maintained a symptom diary until well for two days or a maximum of 14 days and collected 5 sequential mid-turbinate swabs to measure viral shedding. The intervention arm prepared hypertonic saline and performed HSNIG. We recruited 68 participants (2.6 participants/week; November 2014-March 2015). A participant declined after randomisation. Another was on antibiotics and hence removed (Intervention:32, Control:34). Follow up data was available from 61 (Intervention:30, Control:31). 87% found HSNIG acceptable, 93% thought HSNIG made a difference to their symptoms. In the intervention arm, duration of illness was lower by 1.9 days (p = 0.01), over-the-counter medications (OTCM) use by 36% (p = 0.004), transmission within household contacts by 35% (p = 0.006) and viral shedding by ≥0.5 log
    Mesh-Begriff(e) Adult ; Common Cold/therapy ; Common Cold/virology ; Feedback ; Female ; Humans ; Male ; Nasal Lavage ; Pilot Projects ; Saline Solution, Hypertonic/pharmacology ; Virus Shedding/drug effects
    Chemische Substanzen Saline Solution, Hypertonic
    Schlagwörter covid19
    Sprache Englisch
    Erscheinungsdatum 2019-01-31
    Erscheinungsland England
    Dokumenttyp Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-018-37703-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Zusatzmaterialien

    Kategorien

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

  3. Artikel: Hypertonic saline nasal irrigation and gargling should be considered as a treatment option for COVID-19

    Ramalingam, Sandeep / Graham, Catriona / Dove, Jenny / Morrice, Lynn / Sheikh, Aziz

    J Glob Health

    Schlagwörter covid19
    Verlag WHO
    Dokumenttyp Artikel
    Anmerkung WHO #Covidence: #32395245
    Datenquelle COVID19

    Kategorien

    Fernleihe an ZB MED

    Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.

Zum Seitenanfang