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  1. Artikel ; Online: Molecular architectures of iron complexes for oxygen reduction catalysis-Activity enhancement by hydroxide ions coupling.

    Ei Phyu Win, Poe / Yang, Jiahui / Ning, Shuwang / Huang, Xiang / Fu, Gengtao / Sun, Qiming / Xia, Xing-Hua / Wang, Jiong

    Proceedings of the National Academy of Sciences of the United States of America

    2024  Band 121, Heft 11, Seite(n) e2316553121

    Abstract: Developing cost-effective and high-performance electrocatalysts for oxygen reduction reaction (ORR) is critical for clean energy generation. Here, we propose an approach to the synthesis of iron phthalocyanine nanotubes (FePc NTs) as a highly active and ... ...

    Abstract Developing cost-effective and high-performance electrocatalysts for oxygen reduction reaction (ORR) is critical for clean energy generation. Here, we propose an approach to the synthesis of iron phthalocyanine nanotubes (FePc NTs) as a highly active and selective electrocatalyst for ORR. The performance is significantly superior to FePc in randomly aggregated and molecularly dispersed states, as well as the commercial Pt/C catalyst. When FePc NTs are anchored on graphene, the resulting architecture shifts the ORR potentials above the redox potentials of Fe
    Sprache Englisch
    Erscheinungsdatum 2024-03-04
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2316553121
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Correction

    Ei Phyu Win / Kyaw Kyaw Win / Sonoko D Bellingrath-Kimura / Aung Zaw Oo

    PLoS ONE, Vol 17, Iss 1, p e

    Influence of rice varieties, organic manure and water management on greenhouse gas emissions from paddy rice soils.

    2022  Band 0263554

    Abstract: This corrects the article DOI:10.1371/journal.pone.0253755.]. ...

    Abstract [This corrects the article DOI:10.1371/journal.pone.0253755.].
    Schlagwörter Medicine ; R ; Science ; Q
    Sprache Englisch
    Erscheinungsdatum 2022-01-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
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  3. Artikel ; Online: Correction

    Ei Phyu Win / Kyaw Kyaw Win / Sonoko D. Bellingrath-Kimura / Aung Zaw Oo

    PLoS ONE, Vol 17, Iss

    Influence of rice varieties, organic manure and water management on greenhouse gas emissions from paddy rice soils

    2022  Band 1

    Schlagwörter Medicine ; R ; Science ; Q
    Sprache Englisch
    Erscheinungsdatum 2022-01-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
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  4. Artikel ; Online: Influence of rice varieties, organic manure and water management on greenhouse gas emissions from paddy rice soils.

    Ei Phyu Win / Kyaw Kyaw Win / Sonoko D Bellingrath-Kimura / Aung Zaw Oo

    PLoS ONE, Vol 16, Iss 6, p e

    2021  Band 0253755

    Abstract: The study is focused on impact of manure application, rice varieties and water management on greenhouse gas (GHG) emissions from paddy rice soil in pot experiment. The objectives of this study were a) to assess the effect of different types of manure ... ...

    Abstract The study is focused on impact of manure application, rice varieties and water management on greenhouse gas (GHG) emissions from paddy rice soil in pot experiment. The objectives of this study were a) to assess the effect of different types of manure amendments and rice varieties on greenhouse gas emissions and b) to determine the optimum manure application rate to increase rice yield while mitigating GHG emissions under alternate wetting and drying irrigation in paddy rice production. The first pot experiment was conducted at the Department of Agronomy, Yezin Agricultural University, Myanmar, in the wet season from June to October 2016. Two different organic manures (compost and cow dung) and control (no manure), and two rice varieties; Manawthukha (135 days) and IR-50 (115 days), were tested. The results showed that cumulative CH4 emission from Manawthukha (1.084 g CH4 kg-1 soil) was significantly higher than that from IR-50 (0.683 g CH4 kg-1 soil) (P<0.0046) with yield increase (P<0.0164) because of the longer growth duration of the former. In contrast, higher cumulative nitrous oxide emissions were found for IR-50 (2.644 mg N2O kg-1 soil) than for Manawthukha (2.585 mg N2O kg-1 soil). However, IR-50 showed less global warming potential (GWP) than Manawthukha (P<0.0050). Although not significant, the numerically lowest CH4 and N2O emissions were observed in the cow dung manure treatment (0.808 g CH4 kg-1 soil, 2.135 mg N2O kg-1 soil) compared to those of the control and compost. To determine the effect of water management and organic manures on greenhouse gas emissions, second pot experiments were conducted in Madaya township during the dry and wet seasons from February to October 2017. Two water management practices {continuous flooding (CF) and alternate wetting and drying (AWD)} and four cow dung manure rates {(1) 0 (2) 2.5 t ha-1 (3) 5 t ha-1 (4) 7.5 t ha-1} were tested. The different cow dung manure rates did not significantly affect grain yield or greenhouse gas emissions in this experiment. ...
    Schlagwörter Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 571
    Sprache Englisch
    Erscheinungsdatum 2021-01-01T00:00:00Z
    Verlag Public Library of Science (PLoS)
    Dokumenttyp Artikel ; Online
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  5. Artikel ; Online: First Detection of Mycobacterium tuberculosis Clinical Isolates Harboring I491F Borderline Resistance

    Mon, Aye Su / Ei, Phyu Win / Htwe, Mi Mi / Nyunt, Myat Htut / Win, Su Mon / Nyunt, Wint Wint / Myint, Zaw / Aung, Wah Wah

    Antimicrobial agents and chemotherapy

    2022  Band 66, Heft 12, Seite(n) e0092522

    Mesh-Begriff(e) Mycobacterium tuberculosis ; Myanmar ; Mutation ; Antitubercular Agents/pharmacology ; DNA-Directed RNA Polymerases/genetics ; Drug Resistance, Bacterial/genetics ; Bacterial Proteins/genetics ; Antibiotics, Antitubercular/pharmacology
    Chemische Substanzen Antitubercular Agents ; DNA-Directed RNA Polymerases (EC 2.7.7.6) ; Bacterial Proteins ; Antibiotics, Antitubercular
    Sprache Englisch
    Erscheinungsdatum 2022-11-07
    Erscheinungsland United States
    Dokumenttyp Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/aac.00925-22
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Evaluation of the QuantaMatrix Multiplexed Assay Platform for Molecular Diagnosis of Multidrug- and Extensively Drug-Resistant Tuberculosis Using Clinical Strains Isolated in Myanmar.

    Chang, Yunhee / Kim, Seoyong / Kim, Yeun / Ei, Phyu Win / Hwang, Dasom / Lee, Jongseok / Chang, Chulhun L / Lee, Hyeyoung

    Annals of laboratory medicine

    2019  Band 40, Heft 2, Seite(n) 142–147

    Abstract: Background: Although the incidence of tuberculosis (TB) is decreasing, cases of multidrug-resistant (MDR) TB and extensively drug-resistant (XDR) TB continue to increase. As conventional phenotype drug susceptibility testing (pDST) takes six to eight ... ...

    Abstract Background: Although the incidence of tuberculosis (TB) is decreasing, cases of multidrug-resistant (MDR) TB and extensively drug-resistant (XDR) TB continue to increase. As conventional phenotype drug susceptibility testing (pDST) takes six to eight weeks, molecular assays are widely used to determine drug resistance. we developed QuantaMatrix Multiplexed Assay Platform (QMAP) MDR/XDR assay (QuantaMatrix Inc., Seoul, Korea) that can simultaneously detect mutations related to both first- and second-line drug resistance (rifampin, isoniazid, ethambutol, fluoroquinolones, second-line injectable drugs, and streptomycin).
    Methods: We used 190 clinical
    Results: QMAP results were 87.9% (167/190) concordant with pDST results. In the 23 isolates with discordant results, the QMAP and DNA sequencing results completely matched.
    Conclusions: The QMAP MDR/XDR assay can detect all known DNA mutations associated with drug resistance for both MDR- and XDR-MTB strains. It can be used for molecular diagnosis of MDR- and XDR-TB to rapidly initiate appropriate anti-TB drug therapy.
    Mesh-Begriff(e) Antitubercular Agents/pharmacology ; Antitubercular Agents/therapeutic use ; DNA, Bacterial/genetics ; DNA, Bacterial/metabolism ; Drug Resistance, Multiple, Bacterial/genetics ; Extensively Drug-Resistant Tuberculosis/diagnosis ; Extensively Drug-Resistant Tuberculosis/drug therapy ; Humans ; Microbial Sensitivity Tests ; Multiplex Polymerase Chain Reaction/methods ; Mutation ; Myanmar ; Mycobacterium tuberculosis/genetics ; Mycobacterium tuberculosis/isolation & purification ; Phenotype ; Sequence Analysis, DNA ; Tuberculosis, Multidrug-Resistant/diagnosis ; Tuberculosis, Multidrug-Resistant/drug therapy
    Chemische Substanzen Antitubercular Agents ; DNA, Bacterial
    Sprache Englisch
    Erscheinungsdatum 2019-10-24
    Erscheinungsland Korea (South)
    Dokumenttyp Evaluation Study ; Journal Article
    ZDB-ID 2677441-0
    ISSN 2234-3814 ; 2234-3806
    ISSN (online) 2234-3814
    ISSN 2234-3806
    DOI 10.3343/alm.2020.40.2.142
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Molecular Strain Typing of Mycobacterium tuberculosis: a Review of Frequently Used Methods.

    Ei, Phyu Win / Aung, Wah Wah / Lee, Jong Seok / Choi, Go Eun / Chang, Chulhun L

    Journal of Korean medical science

    2016  Band 31, Heft 11, Seite(n) 1673–1683

    Abstract: Tuberculosis, caused by the bacterium Mycobacterium tuberculosis, remains one of the most serious global health problems. Molecular typing of M. tuberculosis has been used for various epidemiologic purposes as well as for clinical management. Currently, ... ...

    Abstract Tuberculosis, caused by the bacterium Mycobacterium tuberculosis, remains one of the most serious global health problems. Molecular typing of M. tuberculosis has been used for various epidemiologic purposes as well as for clinical management. Currently, many techniques are available to type M. tuberculosis. Choosing the most appropriate technique in accordance with the existing laboratory conditions and the specific features of the geographic region is important. Insertion sequence IS6110-based restriction fragment length polymorphism (RFLP) analysis is considered the gold standard for the molecular epidemiologic investigations of tuberculosis. However, other polymerase chain reaction-based methods such as spacer oligonucleotide typing (spoligotyping), which detects 43 spacer sequence-interspersing direct repeats (DRs) in the genomic DR region; mycobacterial interspersed repetitive units-variable number tandem repeats, (MIRU-VNTR), which determines the number and size of tandem repetitive DNA sequences; repetitive-sequence-based PCR (rep-PCR), which provides high-throughput genotypic fingerprinting of multiple Mycobacterium species; and the recently developed genome-based whole genome sequencing methods demonstrate similar discriminatory power and greater convenience. This review focuses on techniques frequently used for the molecular typing of M. tuberculosis and discusses their general aspects and applications.
    Mesh-Begriff(e) DNA Transposable Elements/genetics ; High-Throughput Nucleotide Sequencing ; Humans ; Molecular Typing/methods ; Mycobacterium tuberculosis/genetics ; Mycobacterium tuberculosis/isolation & purification ; Mycobacterium tuberculosis/metabolism ; Nucleic Acid Hybridization ; Polymerase Chain Reaction ; Polymorphism, Restriction Fragment Length ; Tandem Repeat Sequences/genetics ; Tuberculosis/microbiology
    Chemische Substanzen DNA Transposable Elements
    Sprache Englisch
    Erscheinungsdatum 2016-10-05
    Erscheinungsland Korea (South)
    Dokumenttyp Journal Article ; Review
    ZDB-ID 639262-3
    ISSN 1598-6357 ; 1011-8934
    ISSN (online) 1598-6357
    ISSN 1011-8934
    DOI 10.3346/jkms.2016.31.11.1673
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Pyrazinamide resistance and pncA mutations in drug resistant Mycobacterium tuberculosis clinical isolates from Myanmar.

    Ei, Phyu Win / Mon, Aye Su / Htwe, Mi Mi / Win, Su Mon / Aye, Kay Thi / San, Lai Lai / Zaw, Ni Ni / Nyunt, Wint Wint / Myint, Zaw / Lee, Jong Seok / Aung, Wah Wah

    Tuberculosis (Edinburgh, Scotland)

    2020  Band 125, Seite(n) 102013

    Abstract: Pyrazinamide (PZA) is an important anti-tuberculosis drug, which is active against semi-dormant bacilli and used as a component of first-line drugs and drug-resistant tuberculosis regimens. Mutations in pncA and its promoter region are main cause of PZA ... ...

    Abstract Pyrazinamide (PZA) is an important anti-tuberculosis drug, which is active against semi-dormant bacilli and used as a component of first-line drugs and drug-resistant tuberculosis regimens. Mutations in pncA and its promoter region are main cause of PZA resistance. There are limited PZA susceptibility data as there is no routine drug susceptibility testing (DST) for PZA. This study was aimed to determine the proportion of PZA resistance among rifampicin-resistant tuberculosis patients and to identify mutations which are responsible for PZA resistance in pncA and its promoter region. Liquid-based DST was performed to detect PZA susceptibility on 192 culture positive rifampicin-resistant isolates collected from National Tuberculosis Reference Laboratory. Sequencing on pncA including its promoter region was performed and analysis was done on 157 isolates. Phenotypic PZA resistance was detected in 58.9% of isolates. Sixty-five different mutations were distributed in pncA or promoter region of 82 isolates. Sensitivity and specificity of pncA sequencing in detection of PZA resistance showed 89.8% and 95.6% respectively. High proportion of PZA resistance among rifampicin-resistant cases highlighted the need for effective treatment regimen development for PZA-resistant MDR-TB. It is also suggested that routine PZA susceptibility test should be incorporated to treatment monitoring regimen and National Drug Resistance surveys.
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antitubercular Agents/pharmacology ; DNA Mutational Analysis ; DNA, Bacterial/genetics ; Drug Resistance, Multiple, Bacterial/genetics ; Female ; Genotype ; Humans ; Incidence ; Male ; Middle Aged ; Mutation ; Myanmar/epidemiology ; Mycobacterium tuberculosis/genetics ; Mycobacterium tuberculosis/isolation & purification ; Pyrazinamide/pharmacology ; Retrospective Studies ; Tuberculosis, Multidrug-Resistant/drug therapy ; Tuberculosis, Multidrug-Resistant/epidemiology ; Tuberculosis, Multidrug-Resistant/microbiology ; Young Adult
    Chemische Substanzen Antitubercular Agents ; DNA, Bacterial ; Pyrazinamide (2KNI5N06TI)
    Sprache Englisch
    Erscheinungsdatum 2020-10-27
    Erscheinungsland Scotland
    Dokumenttyp Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2046804-0
    ISSN 1873-281X ; 1472-9792
    ISSN (online) 1873-281X
    ISSN 1472-9792
    DOI 10.1016/j.tube.2020.102013
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  9. Artikel: Genotypes and genetic characters of Mycobacterium tuberculosis from Myanmar using three typing methods

    Ei, Phyu Win / Lee, Jong Seok / Aung, Wah Wah / Yeun, Kim / Korma, Workneh / Nyunt, Wint Wint / Swe, Thyn Lei / Htwe, Mi Mi / Win, Su Mon / Aung, Si Thu / Chang, Chulhun L / Lee, Hyeyoung

    Infection, genetics, and evolution. 2019 Nov., v. 75

    2019  

    Abstract: Knowledge on basic characteristics of Mycobacterium tuberculosis (MTB) is helpful to understand the disease epidemiology and support the prediction of clinical outcome of the disease. The aim of this study was to detect the genotypes and genotypic ... ...

    Abstract Knowledge on basic characteristics of Mycobacterium tuberculosis (MTB) is helpful to understand the disease epidemiology and support the prediction of clinical outcome of the disease. The aim of this study was to detect the genotypes and genotypic characters of clinical Mycobacterium tuberculosis (MTB) isolates from new and retreatment rifampicin-resistant patients using three different genotyping methods. Mycobacterial interspersed repetitive units-variable number tandem repeat (MIRU-VNTR) typing was used to determine the diversity of 222 clinical isolates. Spoligotyping and IS6110-restriction fragment length polymorphism (RFLP) typing were also used to investigate the genetic characters of 105 MTB strains. Among the 15 genotypes detected by MIRU-VNTR, Beijing strains were the most prevalent of all strains (54.8%); new cases (40.5%) and retreatment cases (69.4%), followed by EAI strain. Spoligotyping categorized the strains into 11 lineages and 13 orphans whereas 96 different IS6110 patterns were identified using RFLP method. The mode number of IS6110 was 18 and 20. Higher band numbers were found in Beijing genotype (p < 0.001). Clustering rates by spoligotyping, MIRU-VNTR and IS6110-RFLP typing were 0.714, 0.004 and 0.085, respectively. Discriminatory powers of spoligotyping, MIRU-VNTR typing and IS6110-RFLP typing were 0.637, 1.000 and 0.997, respectively. Dominant Beijing genotype in both new and retreatment cases denoting that prevailing tuberculosis in Myanmar changed from EAI to Beijing lineage.
    Schlagwörter Mycobacterium tuberculosis ; epidemiology ; evolution ; genotype ; genotyping ; infection ; prediction ; tuberculosis ; China ; Myanmar
    Sprache Englisch
    Erscheinungsverlauf 2019-11
    Erscheinungsort Elsevier B.V.
    Dokumenttyp Artikel
    Anmerkung NAL-AP-2-clean
    ZDB-ID 2037068-4
    ISSN 1567-1348
    ISSN 1567-1348
    DOI 10.1016/j.meegid.2019.104005
    Datenquelle NAL Katalog (AGRICOLA)

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  10. Artikel ; Online: Genotypes and genetic characters of Mycobacterium tuberculosis from Myanmar using three typing methods.

    Ei, Phyu Win / Lee, Jong Seok / Aung, Wah Wah / Yeun, Kim / Korma, Workneh / Nyunt, Wint Wint / Swe, Thyn Lei / Htwe, Mi Mi / Win, Su Mon / Aung, Si Thu / Chang, Chulhun L / Lee, Hyeyoung

    Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

    2019  Band 75, Seite(n) 104005

    Abstract: Knowledge on basic characteristics of Mycobacterium tuberculosis (MTB) is helpful to understand the disease epidemiology and support the prediction of clinical outcome of the disease. The aim of this study was to detect the genotypes and genotypic ... ...

    Abstract Knowledge on basic characteristics of Mycobacterium tuberculosis (MTB) is helpful to understand the disease epidemiology and support the prediction of clinical outcome of the disease. The aim of this study was to detect the genotypes and genotypic characters of clinical Mycobacterium tuberculosis (MTB) isolates from new and retreatment rifampicin-resistant patients using three different genotyping methods. Mycobacterial interspersed repetitive units-variable number tandem repeat (MIRU-VNTR) typing was used to determine the diversity of 222 clinical isolates. Spoligotyping and IS6110-restriction fragment length polymorphism (RFLP) typing were also used to investigate the genetic characters of 105 MTB strains. Among the 15 genotypes detected by MIRU-VNTR, Beijing strains were the most prevalent of all strains (54.8%); new cases (40.5%) and retreatment cases (69.4%), followed by EAI strain. Spoligotyping categorized the strains into 11 lineages and 13 orphans whereas 96 different IS6110 patterns were identified using RFLP method. The mode number of IS6110 was 18 and 20. Higher band numbers were found in Beijing genotype (p < 0.001). Clustering rates by spoligotyping, MIRU-VNTR and IS6110-RFLP typing were 0.714, 0.004 and 0.085, respectively. Discriminatory powers of spoligotyping, MIRU-VNTR typing and IS6110-RFLP typing were 0.637, 1.000 and 0.997, respectively. Dominant Beijing genotype in both new and retreatment cases denoting that prevailing tuberculosis in Myanmar changed from EAI to Beijing lineage.
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Genetic Variation ; Genotype ; Geography ; Humans ; Male ; Middle Aged ; Minisatellite Repeats ; Molecular Epidemiology ; Molecular Typing ; Myanmar/epidemiology ; Mycobacterium tuberculosis/classification ; Mycobacterium tuberculosis/genetics ; Phylogeny ; Polymorphism, Restriction Fragment Length ; Tuberculosis/epidemiology ; Tuberculosis/microbiology ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2019-08-19
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2037068-4
    ISSN 1567-7257 ; 1567-1348
    ISSN (online) 1567-7257
    ISSN 1567-1348
    DOI 10.1016/j.meegid.2019.104005
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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