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  1. AU="Elizabeth Noble"
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  1. Article ; Online: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.

    Ergen, Elizabeth Noble / Hughey, Lauren C

    JAMA dermatology

    2017  Volume 153, Issue 12, Page(s) 1344

    MeSH term(s) Humans ; Stevens-Johnson Syndrome/diagnosis
    Language English
    Publishing date 2017-12-12
    Publishing country United States
    Document type Journal Article ; Patient Education Handout
    ZDB-ID 2701761-8
    ISSN 2168-6084 ; 2168-6068
    ISSN (online) 2168-6084
    ISSN 2168-6068
    DOI 10.1001/jamadermatol.2017.3957
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui VI Zs.32: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Two mouse models of Alzheimer's disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein.

    Silvia A Purro / Michael Farmer / Elizabeth Noble / Claire J Sarell / Megan Powell / Daniel Yip / Lauren Giggins / Leila Zakka / David X Thomas / Mark Farrow / Andrew J Nicoll / Dominic Walsh / John Collinge

    PLoS ONE, Vol 18, Iss 11, p e

    2023  Volume 0294465

    Abstract: Oligomers formed from monomers of the amyloid β-protein (Aβ) are thought to be central to the pathogenesis of Alzheimer's disease (AD). Unsurprisingly for a complex disease, current mouse models of AD fail to fully mimic the clinical disease in humans. ... ...

    Abstract Oligomers formed from monomers of the amyloid β-protein (Aβ) are thought to be central to the pathogenesis of Alzheimer's disease (AD). Unsurprisingly for a complex disease, current mouse models of AD fail to fully mimic the clinical disease in humans. Moreover, results obtained in a given mouse model are not always reproduced in a different model. Cellular prion protein (PrPC) is now an established receptor for Aβ oligomers. However, studies of the Aβ-PrPC interaction in different mouse models have yielded contradictory results. Here we performed a longitudinal study assessing a range of biochemical and histological features in the commonly used J20 and APP-PS1 mouse models. Our analysis demonstrated that PrPC ablation had no effect on amyloid accumulation or oligomer production. However, we found that APP-PS1 mice had higher levels of oligomers, that these could bind to recombinant PrPC, and were recognised by the OC antibody which distinguishes parallel, in register fibrils. On the other hand, J20 mice had a lower level of Aβ oligomers, which did not interact with PrPC when tested in vitro and were OC-negative. These results suggest the two mouse models produce diverse Aβ assemblies that could interact with different targets, highlighting the necessity to characterise the conformation of the Aβ oligomers concomitantly with the toxic cascade elicited by them. Our results provide an explanation for the apparent contradictory results found in APP-PS1 mice and the J20 mouse line in regards to Aβ toxicity mediated by PrPC.
    Keywords Medicine ; R ; Science ; Q
    Subject code 572
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Cutaneous leishmaniasis: an emerging infectious disease in travelers.

    Ergen, Elizabeth Noble / King, Allison Hutsell / Tuli, Malika

    Cutis

    2015  Volume 96, Issue 4, Page(s) E22–6

    Abstract: Leishmaniasis describes any of 3 diseases caused by protozoan parasites of the genus Leishmania, the most common of which is cutaneous leishmaniasis. The majority of cutaneous cases occur in Central and South America, the Mediterranean basin, the Middle ... ...

    Abstract Leishmaniasis describes any of 3 diseases caused by protozoan parasites of the genus Leishmania, the most common of which is cutaneous leishmaniasis. The majority of cutaneous cases occur in Central and South America, the Mediterranean basin, the Middle East, and Central Asia. Most cases diagnosed among nonmilitary personnel in the United States are acquired in Mexico and Central America. Here, we present the case of an American tourist who developed localized cutaneous leishmaniasis 2 weeks after returning from Costa Rica. After undergoing several unsuccessful rounds of empiric antibiotic treatment for a presumed Staphylococcus aureus skin infection, the patient was referred to our dermatology clinic where cutaneous leishmaniasis was diagnosed by tissue biopsy. This case highlights the importance of cutaneous leishmaniasis as an emerging infectious disease that may be misdiagnosed due to its rarity and varied clinical presentation as well as the limited use of tissue biopsy in general practice. We also provide relevant background information on cutaneous leishmaniasis, a rhyming poem, and an illustration in order to promote greater awareness of this disease and assist clinicians with its diagnosis.
    MeSH term(s) Adult ; Biopsy ; Costa Rica ; Diagnostic Errors ; Humans ; Leishmaniasis, Cutaneous/diagnosis ; Leishmaniasis, Cutaneous/pathology ; Male ; Travel
    Language English
    Publishing date 2015-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 391840-3
    ISSN 2326-6929 ; 0011-4162 ; 0151-9522
    ISSN (online) 2326-6929
    ISSN 0011-4162 ; 0151-9522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1315: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 44: Show issues

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  4. Article ; Online: In vivo label-free mapping of the effect of a photosystem II inhibiting herbicide in plants using chlorophyll fluorescence lifetime

    Elizabeth Noble / Sunil Kumar / Frederik G. Görlitz / Chris Stain / Chris Dunsby / Paul M. W. French

    Plant Methods, Vol 13, Iss 1, Pp 1-

    2017  Volume 16

    Abstract: Abstract Background In order to better understand and improve the mode of action of agrochemicals, it is useful to be able to visualize their uptake and distribution in vivo, non-invasively and, ideally, in the field. Here we explore the potential of ... ...

    Abstract Abstract Background In order to better understand and improve the mode of action of agrochemicals, it is useful to be able to visualize their uptake and distribution in vivo, non-invasively and, ideally, in the field. Here we explore the potential of plant autofluorescence (specifically chlorophyll fluorescence) to provide a readout of herbicide action across the scales utilising multiphoton-excited fluorescence lifetime imaging, wide-field single-photon excited fluorescence lifetime imaging and single point fluorescence lifetime measurements via a fibre-optic probe. Results Our studies indicate that changes in chlorophyll fluorescence lifetime can be utilised as an indirect readout of a photosystem II inhibiting herbicide activity in living plant leaves at three different scales: cellular (~μm), single point (~1 mm2) and macroscopic (~8 × 6 mm2 of a leaf). Multiphoton excited fluorescence lifetime imaging of Triticum aestivum leaves indicated that there is an increase in the spatially averaged chlorophyll fluorescence lifetime of leaves treated with Flagon EC—a photosystem II inhibiting herbicide. The untreated leaf exhibited an average lifetime of 560 ± 30 ps while the leaf imaged 2 h post treatment exhibited an increased lifetime of 2000 ± 440 ps in different fields of view. The results from in vivo wide-field single-photon excited fluorescence lifetime imaging excited at 440 nm indicated an increase in chlorophyll fluorescence lifetime from 521 ps in an untreated leaf to 1000 ps, just 3 min after treating the same leaf with Flagon EC, and to 2150 ps after 27 min. In vivo single point fluorescence lifetime measurements demonstrated a similar increase in chlorophyll fluorescence lifetime. Untreated leaf presented a fluorescence lifetime of 435 ps in the 440 nm excited chlorophyll channel, CH4 (620–710 nm). In the first 5 min after treatment, mean fluorescence lifetime is observed to have increased to 1 ns and then to 1.3 ns after 60 min. For all these in vivo plant autofluorescence lifetime measurements, the ...
    Keywords Fluorescence spectroscopy ; Plant ; FLIM ; Herbicide ; Photosystem II ; Chlorophyll fluorescence lifetime ; Plant culture ; SB1-1110 ; Biology (General) ; QH301-705.5
    Subject code 580 ; 500
    Language English
    Publishing date 2017-06-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Guthrie, Samuel

    Shor, Elizabeth Noble

    American national biography Vol. 9

    1999  Volume 9

    Author's details Elizabeth Noble Shor
    MeSH term(s) Chemistry ; Physicians ; History of Medicine ; History, 19th Century ; History, 20th Century
    Keywords United States
    Language English
    Size p. 743-744.
    Publisher Oxford University Press
    Publishing place New York
    Document type Article
    ISBN 0195206355 ; 9780195206357
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Article: Chandler, Charles Frederick

    Shor, Elizabeth Noble

    American national biography Vol.4

    1999  Volume 4

    Author's details Elizabeth Noble Shor
    MeSH term(s) Pharmacy ; Public Health ; History of Medicine ; History, 19th Century ; History, 20th Century ; Medicine
    Keywords United States
    Language English
    Size p. 658-659.
    Publisher Oxford University Press
    Publishing place New York
    Document type Article
    ISBN 0195206355 ; 9780195206357
    Database Catalogue of the US National Library of Medicine (NLM)

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  7. Article: Prescott, Samuel Cate

    Shor, Elizabeth Noble

    American national biography v.17

    1999  

    Institution Massachusetts Institute of Technology
    Author's details Elizabeth Noble Shor
    MeSH term(s) Bacteriology ; Public Health ; History of Medicine ; History, 19th Century ; History, 20th Century
    Keywords United States
    Language English
    Size p. 833-834.
    Publisher Oxford University Press
    Publishing place New York
    Document type Article
    ISBN 0195206355 ; 9780195206357
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Article: Scholander, Per Fredrik Thorkelsson

    Shor, Elizabeth Noble

    American national biography v.19

    1999  

    Author's details Elizabeth Noble Shor
    MeSH term(s) Physiology ; History of Medicine ; History, 20th Century
    Keywords United States ; Norway
    Language English
    Size p. 418-419.
    Publisher Oxford University Press
    Publishing place New York
    Document type Article
    ISBN 0195206355 ; 9780195206357
    Database Catalogue of the US National Library of Medicine (NLM)

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    Order via subito

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    Inter-library loan at ZB MED

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  9. Article: Pitcher, Zina

    Shor, Elizabeth Noble

    American national biography v.17

    1999  

    Author's details Elizabeth Noble Shor
    MeSH term(s) Physicians ; Michigan ; Education ; History of Medicine ; History, 18th Century
    Keywords United States
    Language English
    Size p. 565-566.
    Publisher Oxford University Press
    Publishing place New York
    Document type Article
    ISBN 0195206355 ; 9780195206357
    Database Catalogue of the US National Library of Medicine (NLM)

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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  10. Article: Wolman, Abel

    Shor, Elizabeth Noble

    American national biography v.23

    1999  

    Author's details Elizabeth Noble Shor
    MeSH term(s) Public Health ; Bacteriology ; History of Medicine ; History, 20th Century
    Keywords United States
    Language English
    Size p. 745-746.
    Publisher Oxford University Press
    Publishing place New York
    Document type Article
    ISBN 0195206355 ; 9780195206357
    Database Catalogue of the US National Library of Medicine (NLM)

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    Kategorien

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