Artikel ; Online: Population-specific causal disease effect sizes in functionally important regions impacted by selection
Nature Communications, Vol 12, Iss 1, Pp 1-
2021 Band 15
Abstract: Trans-ethnic genetic correlation is significantly less than 1 for many diseases. Here, the authors stratify this correlation by genomic annotations, finding that loci whose causal disease effect sizes differ between ethnicities are likely impacted by ... ...
| Abstract | Trans-ethnic genetic correlation is significantly less than 1 for many diseases. Here, the authors stratify this correlation by genomic annotations, finding that loci whose causal disease effect sizes differ between ethnicities are likely impacted by selection, particularly positive selection. |
|---|---|
| Schlagwörter | Science ; Q |
| Sprache | Englisch |
| Erscheinungsdatum | 2021-02-01T00:00:00Z |
| Verlag | Nature Portfolio |
| Dokumenttyp | Artikel ; Online |
| Datenquelle | BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl) |
Volltext online
Zusatzmaterialien
Kategorien
Fernleihe an ZB MED
Sie können sich den gewünschten Titel als lokale Nutzerin oder lokaler Nutzer von ZB MED direkt an den Standort Köln schicken lassen.