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  1. Artikel: Adult pancreatoblastoma with atypical histological morphology combined with familial adenomatous polyposis: a rare case report.

    Wang, Ying-Xia / Fan, Su-Su / Peng, Xue-Rong / Zhu, Yu-Shan / Zhang, Xuan

    Frontiers in oncology

    2024  Band 14, Seite(n) 1346964

    Abstract: Pancreatoblastoma (PB) is a rare malignant pancreatic epithelial tumor that mostly occurs in children and occasionally occurs in adults. The tumor has acinar cell differentiation and squamous corpuscles/squamous epithelial islands, which are frequently ... ...

    Abstract Pancreatoblastoma (PB) is a rare malignant pancreatic epithelial tumor that mostly occurs in children and occasionally occurs in adults. The tumor has acinar cell differentiation and squamous corpuscles/squamous epithelial islands, which are frequently separated by fibrous bundles. Familial adenomatous polyposis (FAP) is an autosomal dominant inherited disease characterized by the presence of numerous adenomatous polyps in the colon and rectum. Cases of pancreatoblastoma combined with familial adenomatous polyposis (FAP) are rarely reported. A review of a rare case of adult pancreatoblastoma with atypical histological morphology combined with familial adenomatous polyposis is presented herein. In this case, the patient was first diagnosed with familial adenomatous polyposis and subsequently found to have pancreatoblastoma 1 year and 3 months later. This suggests pancreatoblastoma may occur in patients with familial adenomatous polyposis or a family history of the condition, indicating a possible association between the two tumors. Therefore, pancreatoblastoma should be included in a differential diagnosis for FAP patients with a pancreatic mass. The final diagnosis of pancreatoblastoma depends on the pathological diagnosis. Acinar-like cells and squamous corpuscles/squamous epithelial cell islands under light microscopy are the key diagnostic points. This case report also can improve the awareness of clinicians, radiologists, and pathologists on the presence of rare tumor-adult pancreatoblastoma in patients with familial adenomatous polyposis.
    Sprache Englisch
    Erscheinungsdatum 2024-02-28
    Erscheinungsland Switzerland
    Dokumenttyp Case Reports
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2024.1346964
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Solitary Fibrous Tumors of the Lung: A Clinicopathological Analysis of 52 Cases.

    Wang, Ying-Xia / Zhong, Yan / Fan, Su-Su / Zhu, Yu-Shan / Peng, Xue-Rong / Zhang, Xuan

    Current oncology (Toronto, Ont.)

    2023  Band 30, Heft 2, Seite(n) 1784–1793

    Abstract: Objective: To explore the clinicopathological features of solitary fibrous tumors (SFTs) of the lung.: Methods: We collected the clinical data of 52 patients with SFTs of the lung confirmed by pathology, and summarized the clinical, radiological, and ...

    Abstract Objective: To explore the clinicopathological features of solitary fibrous tumors (SFTs) of the lung.
    Methods: We collected the clinical data of 52 patients with SFTs of the lung confirmed by pathology, and summarized the clinical, radiological, and morphological features, the immunophenotypes, and the prognosis of SFTs.
    Results: Fifty-two cases of SFTs of the lung were enrolled in this study, including 51 cases of borderline and 1 case of malignancy, 22 males and 30 females. The average onset age was 52.7 years. The lower lobe of the left lung was the preferred site of SFTs, accounting for 30.77% (16/52). Chest CT showed regular and well-demarcated soft tissue density mass, and the tumor size of most cases (46/52, 88.46%) was 1-10 cm. Morphological features: The distribution of tumor cells showed sparse and dense areas. Tumor cells were spindle-shaped, in whorls or hemangiopericytoma-like conformation. Atypia, mitotic figures, and necrosis were found. Immunohistochemistry showed positive expression of CD34, STAT6, Vimentin, BCL2, and CD99. Ki-67 was ≤ 5% in borderline SFTs and >20% in a malignant SFT.
    Conclusions: Solitary fibrous tumors of the lung occur more frequently in middle-aged and elderly people, and there is no significant difference in gender. The lower lobe of the left lung is the preferred site of SFTs. The size of most SFTs is 1-10 cm. Chest CT shows morphologically regular and well-demarcated soft tissue density mass. Pathologically, SFTs of the lung are mostly borderline and occasionally malignant. Immunohistochemistry shows the positive expression of CD34, STAT6, Vimentin, BCL2, and CD99.
    Mesh-Begriff(e) Aged ; Middle Aged ; Male ; Female ; Humans ; Vimentin ; Severe Fever with Thrombocytopenia Syndrome ; Biomarkers, Tumor/analysis ; Solitary Fibrous Tumors/genetics ; Solitary Fibrous Tumors/metabolism ; Solitary Fibrous Tumors/pathology ; Lung/pathology ; Proto-Oncogene Proteins c-bcl-2
    Chemische Substanzen Vimentin ; Biomarkers, Tumor ; Proto-Oncogene Proteins c-bcl-2
    Sprache Englisch
    Erscheinungsdatum 2023-02-01
    Erscheinungsland Switzerland
    Dokumenttyp Case Reports ; Research Support, Non-U.S. Gov't
    ZDB-ID 1236972-x
    ISSN 1718-7729 ; 1198-0052
    ISSN (online) 1718-7729
    ISSN 1198-0052
    DOI 10.3390/curroncol30020138
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Identification and characterization of Colletotrichum gloeosporioides sensu stricto, the agent of anthracnose disease of Sorbaria sorbifolia in China

    Wang, Qing-Hai / Li, Xiang-Ying / Xu, Ting-Ting / Zhang, Meng-Ai / Yang, Yu-Hui / Feng, Pei-Bo / Fan, Su-Su / Liu, Zhen-Yu

    Journal of general plant pathology. 2021 Mar., v. 87, no. 2

    2021  

    Abstract: The pathogen causing Sorbaria sorbifolia anthracnose in Shandong Province, China was identified as Colletotrichum gloeosporioides sensu stricto using morphological and molecular approaches. The daily growth rate was 13.7 mm/d (25 °C); the optimum for ... ...

    Abstract The pathogen causing Sorbaria sorbifolia anthracnose in Shandong Province, China was identified as Colletotrichum gloeosporioides sensu stricto using morphological and molecular approaches. The daily growth rate was 13.7 mm/d (25 °C); the optimum for growth and conidial germination was 25–30 °C, pH 5.0–9.0.
    Schlagwörter Glomerella cingulata ; Sorbaria sorbifolia ; anthracnose ; conidia ; germination ; pH ; pathogens ; plant pathology ; China
    Sprache Englisch
    Erscheinungsverlauf 2021-03
    Umfang p. 71-76.
    Erscheinungsort Springer Japan
    Dokumenttyp Artikel
    Anmerkung NAL-AP-2-clean
    ZDB-ID 2016032-X
    ISSN 1345-2630
    ISSN 1345-2630
    DOI 10.1007/s10327-020-00973-9
    Datenquelle NAL Katalog (AGRICOLA)

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    Verfügbar in ZB MED Bonn

    Z 3277: Hefte anzeigen

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  4. Artikel ; Online: Small Molecule Inhibitors Specifically Targeting the Type III Secretion System of

    Tao, Hui / Fan, Su-Su / Jiang, Shan / Xiang, Xuwen / Yan, Xiaojing / Zhang, Lian-Hui / Cui, Zi-Ning

    International journal of molecular sciences

    2019  Band 20, Heft 4

    Abstract: The initiative strategy for the development of novel anti-microbial agents usually uses the virulence factors of bacteria as a target, without affecting their growth and survival. The type III secretion system (T3SS), one of the essential virulence ... ...

    Abstract The initiative strategy for the development of novel anti-microbial agents usually uses the virulence factors of bacteria as a target, without affecting their growth and survival. The type III secretion system (T3SS), one of the essential virulence factors in most Gram-negative pathogenic bacteria because of its highly conserved construct, has been regarded as an effective target that developed new anti-microbial drugs.
    Mesh-Begriff(e) Gene Expression Regulation, Bacterial/drug effects ; Genes, Plant ; Oryza/drug effects ; Oryza/genetics ; Oryza/microbiology ; Plant Diseases/microbiology ; Promoter Regions, Genetic ; Small Molecule Libraries/analysis ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/pharmacology ; Nicotiana/microbiology ; Type III Secretion Systems/metabolism ; Xanthomonas/drug effects ; Xanthomonas/growth & development ; Xanthomonas/metabolism
    Chemische Substanzen Small Molecule Libraries ; Type III Secretion Systems
    Sprache Englisch
    Erscheinungsdatum 2019-02-23
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms20040971
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Isolation and characterization of an AHL lactonase gene from Bacillus amyloliquefaciens

    Yin, Xiang-Tian / Xu, Liang / Fan, Su-Su / Xu, Li-Na / Li, Duo-Chuan / Liu, Zhen-Yu

    World journal of microbiology & biotechnology. 2010 Aug., v. 26, no. 8

    2010  

    Abstract: An AHL lactonase gene (aiiA) was PCR amplified from the genomic DNA of Bacillus amyloliquefaciens, with the intact open reading frame of 753 base pair. The gene shares high identity to its homologues present in different Bacillus species. The expression ... ...

    Abstract An AHL lactonase gene (aiiA) was PCR amplified from the genomic DNA of Bacillus amyloliquefaciens, with the intact open reading frame of 753 base pair. The gene shares high identity to its homologues present in different Bacillus species. The expression plasmid carrying a tact aiiA-PEBA gene was constructed and the gene was overproduced in Escherichia coli BL21 (DE3). The product expressed resulted in attenuation and suspension of the infection of Pectobacterium carotovorum subsp. carotovorum on carrot. This study verified the existence of the aiiA gene in B. amyloliquefaciens and provided a prospect of the strain as biocontrol agents with quorum quenching property on bacterial disease control.
    Schlagwörter biological control agents ; Bacillus amyloliquefaciens
    Sprache Englisch
    Erscheinungsverlauf 2010-08
    Umfang p. 1361-1367.
    Verlag Springer Netherlands
    Erscheinungsort Dordrecht
    Dokumenttyp Artikel
    ZDB-ID 1499109-3
    ISSN 1573-0972 ; 0959-3993
    ISSN (online) 1573-0972
    ISSN 0959-3993
    DOI 10.1007/s11274-010-0308-8
    Datenquelle NAL Katalog (AGRICOLA)

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