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  1. Artikel ; Online: Escore eletrocardiográfico: aplicação em ergometria para avaliação do precondicionamento isquêmico.

    Uchida, Augusto / Moffa, Paulo / Hueb, Whady / Cesar, Luiz Antonio Machado / Ferreira, Beatriz Moreira Ayub / Ramires, Jose Antonio Franchini

    Arquivos brasileiros de cardiologia

    2010  Band 95, Heft 4, Seite(n) 486–492

    Abstract: Background: the time for 1.0 mm ST-segment depression (T-1.0mm) adopted to characterize ischemic preconditioning (IPC) in sequential exercise tests is consistent and reproducible; however, it has several limitations.: Objective: to apply an ... ...

    Titelübersetzung Electrocardiographic score: application in exercise test for the assessment of ischemic preconditioning.
    Abstract Background: the time for 1.0 mm ST-segment depression (T-1.0mm) adopted to characterize ischemic preconditioning (IPC) in sequential exercise tests is consistent and reproducible; however, it has several limitations.
    Objective: to apply an electrocardiographic score of myocardial ischemia in sequential exercise tests, comparing it to the conventional T-1.0 mm index.
    Methods: sixty one patients with mean age of 62.2 ± 7.5 years were evaluated; 86.9% were males. A total of 151 tests were analyzed, 116 of which were from patients who completed two assessment phases. The first phase comprised two sequential exercise tests for the documentation of IPC; the second phase, initiated one week later, comprised two more tests carried out under the effect of repaglinide. Two observers who were blind to the tests applied the score.
    Results: Perfect inter and intraobserver agreement was found (Kendall tau-b = 0.96, p < 0.0001, and Kendall tau-b = 0.98, p < 0.0001, respectively). Values of sensitivity and specificity, negative predictive value, positive predictive value and accuracy were 72.41%, 89.29%, 75.8%, 87.5% and 81.0%, respectively.
    Conclusion: the ischemic score is a consistent and reproducible method for the documentation of IPC, and is a feasible alternative to T-1.0 mm.
    Mesh-Begriff(e) Carbamates ; Diabetes Mellitus/drug therapy ; Diabetes Mellitus/physiopathology ; Double-Blind Method ; Electrocardiography/methods ; Electrocardiography/standards ; Ergometry ; Female ; Humans ; Hypoglycemic Agents/therapeutic use ; Ischemic Preconditioning ; Male ; Middle Aged ; Myocardial Ischemia/diagnosis ; Observer Variation ; Piperidines ; Predictive Value of Tests
    Chemische Substanzen Carbamates ; Hypoglycemic Agents ; Piperidines ; repaglinide (668Z8C33LU)
    Sprache Mehrere Sprachen
    Erscheinungsdatum 2010-09-08
    Erscheinungsland Brazil
    Dokumenttyp Comparative Study ; English Abstract ; Journal Article
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.1590/s0066-782x2010005000122
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Exercise-induced left septal fascicular block: an expression of severe myocardial ischemia.

    Uchida, Augusto Hiroshi / Moffa, Paulo Jorge / Riera, Andrés Ricardo Pérez / Ferreira, Beatriz Moreira Ayub

    Indian pacing and electrophysiology journal

    2006  Band 6, Heft 2, Seite(n) 135–138

    Sprache Englisch
    Erscheinungsdatum 2006-04-01
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2123606-9
    ISSN 0972-6292 ; 0972-6292
    ISSN (online) 0972-6292
    ISSN 0972-6292
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: New prognostic score for stable coronary disease evaluation.

    Coutinho Storti, Fernanda / Moffa, Paulo Jorge / Uchida, Augusto H / Hueb, Whady Armindo / Machado César, Luiz Antônio / Ferreira, Beatriz Moreira Ayub / Camargo, Paulo Augusto de / Chalela, William Azem

    Arquivos brasileiros de cardiologia

    2011  Band 96, Heft 5, Seite(n) 411–418

    Abstract: Background: The need to improve the exercise testing accuracy, pushed the development of scores, whose applicability was already broadly recognized.: Objective: Prognostic evaluation of stable coronary disease through a new simplified score.: ... ...

    Abstract Background: The need to improve the exercise testing accuracy, pushed the development of scores, whose applicability was already broadly recognized.
    Objective: Prognostic evaluation of stable coronary disease through a new simplified score.
    Methods: A new score was applied in 372 multivessel coronary patients with preserved ventricular function, 71.8% male, age: 59.5 (± 9.07) years old, randomized to medical treatment, surgery (CABG) or angioplasty (PTCA), with 5 years of follow-up. Cardiovascular death was considered the primary endpoint. Non-fatal myocardial infarction, death and re-intervention were considered for a combined secondary endpoint. The score was based on an equation previously validated, resulting from a sum of one point for: male gender, infarction history, angina, diabetes, insulin use and one point for each decade of life after 40 years old. Positive exercise testing summed one additional point.
    Results: Thirty six deaths was observed (10 in group PTCA, 15 in CABG and 11 in the clinical group), p = 0.61. We observed 93 combined events: 37 in PTCA group, 23 in CABG and 33 in the clinical group (p = 0.058). 247 patients presented clinical score ≥ 5 points and 216 ≥ 6 points. The cutoff point ≥ 5 or ≥ 6 points identified higher risk, p = 0.015 and p = 0.012, respectively. The survival curve showed a different death incidence after the randomization when score reached 06 points or more (p = 0.07), and a distinct incidence of combined events between the patients with score < 6 and ≥ 6 points (p = 0.02).
    Conclusion: The new score was consistent for multiarterial stable coronary disease risk stratification.
    Mesh-Begriff(e) Age Factors ; Angina Pectoris/epidemiology ; Angioplasty, Balloon, Coronary/mortality ; Angioplasty, Balloon, Coronary/statistics & numerical data ; Coronary Artery Bypass/mortality ; Coronary Artery Bypass/statistics & numerical data ; Coronary Disease/mortality ; Diabetes Mellitus/drug therapy ; Epidemiologic Methods ; Exercise Test/methods ; Female ; Humans ; Hypoglycemic Agents/therapeutic use ; Insulin/therapeutic use ; Male ; Middle Aged ; Myocardial Infarction/epidemiology ; Myocardial Infarction/mortality ; Prognosis ; Time Factors
    Chemische Substanzen Hypoglycemic Agents ; Insulin
    Sprache Spanisch
    Erscheinungsdatum 2011-04-15
    Erscheinungsland Brazil
    Dokumenttyp Journal Article ; Randomized Controlled Trial
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.1590/s0066-782x2011005000046
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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