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Artikel: An Oligosaccharide Rich Diet Increases

Lindenberg, Frederikke Christine / Lützhøft, Ditte Olsen / Krych, Lukasz / Fielden, James / Kot, Witold / Frøkiær, Hanne / van Galen, Gaby / Nielsen, Dennis Sandris / Hansen, Axel Kornerup

Frontiers in microbiology

2021  Band 12, Seite(n) 666039

Abstract: Some oligosaccharides induce growth of anti-inflammatory bacterial species and induce regulatory immunity in humans as well as animals. We have shown that the equine gut microbiota and the immune-microbial homeostasis largely stabilize within the first ... ...

Abstract Some oligosaccharides induce growth of anti-inflammatory bacterial species and induce regulatory immunity in humans as well as animals. We have shown that the equine gut microbiota and the immune-microbial homeostasis largely stabilize within the first 50 days of life. Furthermore, we have previously established that certain bacterial species in the equine gut correlated with regulatory immunity. Accordingly, we hypothesized that an oligosaccharide rich diet fed to foals during the first 50 days would increase the abundance of bacterial species associated with regulatory immunity, and that this would influence immune responses in the foals. Eight pregnant mares and their foals were fed an oligosaccharide rich diet from 4 weeks before expected parturition until 49 days post-partum. Six mares and foals served as control. Fecal microbiota from mares and foals was characterized using 16S rRNA gene amplicon high throughput sequencing. On Day 49 the test foals had significantly higher abundances of
Sprache Englisch
Erscheinungsdatum 2021-05-21
Erscheinungsland Switzerland
Dokumenttyp Journal Article
ZDB-ID 2587354-4
ISSN 1664-302X
ISSN 1664-302X
DOI 10.3389/fmicb.2021.666039
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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