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  1. Artikel ; Online: Burden of respiratory syncytial virus diseases among under 5 children in Sub-Saharan Africa

    Fiseha Wadilo Wada / Minyahil Tadesse Boltena / Rawliegh Howe / Fithamlak Bistegen Solomon / Adey Feleke / Tamrayehu Seyoum / Andargachew Mulu / Adane Mihret

    Heliyon, Vol 9, Iss 12, Pp e22211- (2023)

    A systematic review and meta-analysis

    2023  

    Abstract: Background: Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory infections (ALRIs) in young children. To design preventive efforts in sub-Saharan Africa, a better knowledge of the true role of RSV in pediatric ALRIs is ... ...

    Abstract Background: Respiratory syncytial virus (RSV) is the most common cause of acute lower respiratory infections (ALRIs) in young children. To design preventive efforts in sub-Saharan Africa, a better knowledge of the true role of RSV in pediatric ALRIs is required. Therefore we conducted a systematic review and meta-analysis of case–control studies to estimate the etiological role of RSV to ALRIs in under 5 years children in sub-Saharan Africa. Methods: This study was done according to PRISMA guidelines. PubMed, EMBASE, SCOPUS, Web of Sciences databases, and Google Scholar were used to retrieve articles. STATA software version 17 was used for data analysis. The results of all the included studies were standardized to odds ratios (ORs) with accompanying 95 % confidence intervals (95 % CIs) and the pooled estimates of ORs, attributable fraction among the exposed (AFE), and population attributable fraction (PAF) were reported. The heterogeneity was assessed using Cochrane chi-square (I 2) statistics. Result: A total of 6200 cases and 4986 controls from 14 articles that fulfilled the inclusion criteria were included. The pooled prevalence of RSV among cases and controls was 23.52 % [95 % CI (20.68–26.47)] and 4.33 % [95 % CI (3.11–5.73)], respectively. The pooled OR is 7.04 [95 % CI (4.41–11.24)], which indicated a significant association between RSV and ALRI. Among ALRIs cases positive for RSV, the proportion of disease that was not attributable to the background rate (AFE) was 85.8 % [95 % CI (77.3–91.1)]. The fraction of ALRIs children that can be attributed to RSV (PAF) was 20.2 % [95 % CI (16–24.1)]. Conclusion: This study showed clear associations between RSV and ALRI hospitalization in young children in sub-Saharan Africa indicating the need for prophylactic measures against RSV in this age group.
    Schlagwörter Respiratory syncytial virus ; ALRIs ; Children ; Naso/oropharyngeal ; Sub-Saharan Africa ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
    Sprache Englisch
    Erscheinungsdatum 2023-12-01T00:00:00Z
    Verlag Elsevier
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  2. Artikel ; Online: Nasopharyngeal carriage of Streptococcus pneumoniae and antimicrobial susceptibility pattern among school children in South Ethiopia

    Fiseha Wadilo Wada / Efrata Girma Tufa / Tezera Moshago Berheto / Fithamlak Bisetegen Solomon

    BMC Research Notes, Vol 12, Iss 1, Pp 1-

    post-vaccination era

    2019  Band 6

    Abstract: Abstract Objective The aim of this study was to investigate nasopharyngeal carriage rate and antibiotic susceptibility patterns of Streptococcus pneumoniae among school children. Results Three hundred eleven (43.8%) became culture positive for S. ... ...

    Abstract Abstract Objective The aim of this study was to investigate nasopharyngeal carriage rate and antibiotic susceptibility patterns of Streptococcus pneumoniae among school children. Results Three hundred eleven (43.8%) became culture positive for S. pneumoniae. The carriage rate among children, 3–5 years old was 62.5%, which was higher than the carriage rate of 38.6% among 6–13 years old children. Age ≤ 5 years and co-sleeping with siblings remained significantly associated with S. pneumoniae carriage. 155 (49.8%) of the isolates were resistant to co-trimoxazole, 152 (48.9%) of the isolates were resistant to tetracycline, and 88 (28.3%) of isolates were resistant to oxacillin. Multi drug resistant S. pneumoniae was observed in 90 (28.9%) of isolates. There is high prevalence of S. pneumoniae in primary school children in our study area. Relatively high carriage rate of resistance to oxacillin, tetracycline and co-trimoxazole were observed. These findings provide baseline data for future studies to further compare pneumococcal carriage rates and antibiotic resistance patterns.
    Schlagwörter Nasopharyngeal ; Carriage ; S. pneumoniae ; Sodo Zuria Woreda ; Antibiotic ; School children ; Medicine ; R ; Biology (General) ; QH301-705.5 ; Science (General) ; Q1-390
    Sprache Englisch
    Erscheinungsdatum 2019-05-01T00:00:00Z
    Verlag BMC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  3. Artikel ; Online: Non-opportunistic intestinal parasitic infections among HIV-infected individuals at Wolaita Sodo Hospital, South Ethiopia

    Amsalu Arota Amado / Fiseha Wadilo Wada / Fithamlak Solomon Bisetegn / Yishak Abreham Leka

    Journal of Coastal Life Medicine, Vol 4, Iss 5, Pp 353-

    2016  Band 357

    Abstract: Objective: To determine the prevalence of non-opportunistic intestinal helminthic and protozoal infections among HIV-infected individuals and to determine socio-demographic determinants of intestinal parasitosis. Methods: A cross-sectional study was ... ...

    Abstract Objective: To determine the prevalence of non-opportunistic intestinal helminthic and protozoal infections among HIV-infected individuals and to determine socio-demographic determinants of intestinal parasitosis. Methods: A cross-sectional study was conducted on HIV-infected individuals attending antiretroviral therapy clinic of Wolaita Sodo Hospital. Stool in wet mount preparation and formalether concentration technique were used to diagnose intestinal parasitic infection. Sociodemographic variables were collected by using questionnaire. Chi-square test was used to test the associations between intestinal parasitosis and socio-demographic variables. Results: The overall prevalence of non-opportunistic intestinal parasitic infection was 32.4% out of which 11.0% was protozoal infection and 21.4% was helminthic infection. The most common intestinal parasite detected was Ascaris lumbricoides with 12.7% prevalence followed by Giardia lamblia with 7.5% prevalence. The prevalence of Strongyloides stercoralis, hookworm species, Entamoeba histolytica/Entamoeba dispar, Schistosoma mansoni and Taenia species was 2.9%, 1.2%, 3.5%, 1.7% and 2.3% respectively. There was no significant difference in prevalence of intestinal parasite infection with regard to age, sex, residence area, job type and religion of participants but there was a significant association between the educational status and intestinal parasitic infection. The prevalence of intestinal parasitic infection was higher among illiterate participants. Conclusions: Ascaris lumbricoides was the most common intestinal parasite detected in HIVinfected individuals. Giardia lamblia was the most common protozoal parasite observed. Prevalence of intestinal helminthic infection was higher than protozoal infection. Intestinal parasitosis was significantly associated with an educational status of individuals.
    Schlagwörter Intestinal parasitic infection ; HIV-infected individual ; Socio-demographic variables ; Medicine (General) ; R5-920 ; Biology (General) ; QH301-705.5
    Sprache Englisch
    Erscheinungsdatum 2016-05-01T00:00:00Z
    Verlag Journal of Coastal Life Medicine Editorial Office
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel ; Online: Burden of intestinal pathogens and associated factors among asymptomatic food handlers in South Ethiopia

    Fithamlak Bisetegen Solomon / Fiseha Wadilo Wada / Antehun Alemayehu Anjulo / Hailu Chare Koyra / Efrata Girma Tufa

    BMC Research Notes, Vol 11, Iss 1, Pp 1-

    emphasis on salmonellosis

    2018  Band 6

    Abstract: Abstract Objective The study aims to assess the burden of intestinal parasites and Salmonellosis among asymptomatic food handlers at meal serving facilities in Sodo town. Antibiotic resistance was also common and increasing among Salmonella isolates with ...

    Abstract Abstract Objective The study aims to assess the burden of intestinal parasites and Salmonellosis among asymptomatic food handlers at meal serving facilities in Sodo town. Antibiotic resistance was also common and increasing among Salmonella isolates with multidrug resistance as current concern. Result Community based cross-sectional study was carried out from 387 food handlers working in meal serving facilities. Food handlers, 159(41%) had one or more intestinal parasites. A. lumbricoides was the most prevalent parasite 30(7.8%), followed by Taenia species 26(6.7%) and Hook worm 23(5.9%). A total number of 35 Salmonella isolates were found of which Sero-group D was the most frequent, 17(48.5%) followed by Sero-group C, 12(34.3%), and B 6(17.1%). Ten (2.5%) isolates were Salmonella typhi. Raw meat eating, hand washing after toilet and after touching dirty materials showed significant association with intestinal pathogens. Salmonella isolates were highly resistant to ampicillin (85.7%), amoxicillin and tetracycline 74.3% each. Multidrug resistance prevalence of 81.8% was identified. Periodic screening of food handlers is important in order to prevent the transmission of intestinal parasites and Salmonellosis. Treatment needs to be based on accurate laboratory detection to mitigate the spread of drug resistant Salmonella strains.
    Schlagwörter Intestinal parasites ; Salmonella ; Sero-group ; S. typhi ; Antibiotic ; Multi-drug resistance ; Medicine ; R ; Biology (General) ; QH301-705.5 ; Science (General) ; Q1-390
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2018-07-01T00:00:00Z
    Verlag BMC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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