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Artikel ; Online: E.Co.Tech-electrochemical handheld breathalyzer COVID sensing technology.

Banga, Ivneet / Paul, Anirban / France, Kordel / Micklich, Ben / Cardwell, Bret / Micklich, Craig / Prasad, Shalini

Scientific reports

2022  Band 12, Heft 1, Seite(n) 4370

Abstract: Breathomics is widely emerging as a strategy for non-invasive diagnosis of respiratory inflammation. In this study, we have evaluated the metabolic signals associated with Coronavirus (SARS COV-2), mainly the release of nitric oxide in breath. We have ... ...

Abstract Breathomics is widely emerging as a strategy for non-invasive diagnosis of respiratory inflammation. In this study, we have evaluated the metabolic signals associated with Coronavirus (SARS COV-2), mainly the release of nitric oxide in breath. We have demonstrated the utility of a breath analyzer-based sensor platform for the detection of trace amounts of this target species. The sensor surface is modified with Room Temperature Ionic Liquid (RTIL) that allows faster diffusion of the target gas and can be used for gas sensing application. A low limit of detection (LOD) of 50 parts per billion has been achieved with a 95% confidence interval for detection of nitric oxide.. This inhouse designed sensor is incorporated into a breath analyzer system that displays enhanced sensitivity, specificity, linearity, and reproducibility for NO gas monitoring. The developed sensor platform can detect target concentrations of NO ranging from 50 to 250 ppb, using 1-Ethyl-3-methylimidazolium Tetrafluoroborate ([EMIM]BF
Mesh-Begriff(e) Breath Tests ; COVID-19/diagnosis ; Humans ; Ionic Liquids ; Reproducibility of Results ; Technology
Chemische Substanzen Ionic Liquids
Sprache Englisch
Erscheinungsdatum 2022-03-14
Erscheinungsland England
Dokumenttyp Journal Article
ZDB-ID 2615211-3
ISSN 2045-2322 ; 2045-2322
ISSN (online) 2045-2322
ISSN 2045-2322
DOI 10.1038/s41598-022-08321-x
Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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