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  1. Buch: Modelle von Gesundheit und Krankheit

    Franke, Alexa

    (Verlag Hans Huber : Programmbereich Gesundheit)

    2012  

    Verfasserangabe Alexa Franke
    Serientitel Verlag Hans Huber : Programmbereich Gesundheit
    Schlagwörter Public Health ; Disabled Persons ; Disease ; Gesundheit ; Krankheit
    Schlagwörter Erkrankung ; Krankheitszustand ; Krankheiten ; Morbus ; Nosos ; Pathos ; Gesundheitsstatus ; Gesundheitszustand
    Sprache Deutsch
    Umfang 285 S. : Ill., graph. Darst.
    Ausgabenhinweis 3., überarb. Aufl.
    Verlag Huber
    Erscheinungsort Bern
    Erscheinungsland Schweiz
    Dokumenttyp Buch
    Anmerkung Hier auch später erschienene, unveränderte Nachdrucke
    HBZ-ID HT017358476
    ISBN 978-3-456-85120-4 ; 3-456-85120-0 ; 9783456951201 ; 9783456751207 ; 3456951205 ; 3456751206
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  2. Buch ; Online: Kritische Lebensereignisse im Alter - Übergänge gestalten

    Franke, Annette / Heusinger, Josefine / Konopik, Nadine / Wolter, Birgit

    (Forschung und Praxis der Gesundheitsförderung ; Band 49)

    2017  

    Körperschaft Bundeszentrale für Gesundheitliche Aufklärung
    Verfasserangabe Annette Franke, Josefine Heusinger, Nadine Konopik und Birgit Wolter ; Herausgeberin: Bundeszentrale für Gesundheitliche Aufklärung (BZgA)
    Serientitel Forschung und Praxis der Gesundheitsförderung ; Band 49
    Überordnung
    Thema/Rubrik (Code) 610
    Sprache Deutsch
    Umfang 1 Online-Ressource (132 Seiten), Diagramme
    Ausgabenhinweis Auflage 1.2.11.17
    Verlag Bundeszentrale für gesundheitliche Aufklärung (BZgA)
    Erscheinungsort Köln
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Online
    Anmerkung Open Access
    HBZ-ID HT019617586
    ISBN 9783946692386 ; 3946692389
    DOI 10.4126/FRL01-006431164
    Datenquelle Fachrepositorium Lebenswissenschaften

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  3. Buch ; Online ; E-Book: Hirndoping & Co

    Franke, Andreas G.

    die optimierte Gesellschaft

    2019  

    Verfasserangabe Andreas G. Franke
    Sprache Deutsch
    Umfang 1 Online-Ressource (XIII, 212 Seiten), Illustrationen
    Verlag Springer
    Erscheinungsort Berlin
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Online ; E-Book
    Bemerkung Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020297349
    ISBN 978-3-662-58853-6 ; 9783662588529 ; 3-662-58853-6 ; 3662588528
    DOI 10.1007/978-3-662-58853-6
    Datenquelle ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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  4. Artikel ; Online: Mass Spectrometry-Based Immunopeptidomics of Peptides Presented on Human Leukocyte Antigen Proteins.

    ElAbd, Hesham / Franke, Andre

    Methods in molecular biology (Clifton, N.J.)

    2024  Band 2758, Seite(n) 425–443

    Abstract: Human leukocyte antigen (HLA) proteins are a group of glycoproteins that are expressed at the cell surface, where they present peptides to T cells through physical interactions with T-cell receptors (TCRs). Hence, characterizing the set of peptides ... ...

    Abstract Human leukocyte antigen (HLA) proteins are a group of glycoproteins that are expressed at the cell surface, where they present peptides to T cells through physical interactions with T-cell receptors (TCRs). Hence, characterizing the set of peptides presented by HLA proteins, referred to hereafter as the immunopeptidome, is fundamental for neoantigen identification, immunotherapy, and vaccine development. As a result, different methods have been used over the years to identify peptides presented by HLA proteins, including competition assays, peptide microarrays, and yeast display systems. Nonetheless, over the last decade, mass spectrometry-based immunopeptidomics (MS-immunopeptidomics) has emerged as the gold-standard method for identifying peptides presented by HLA proteins. MS-immunopeptidomics enables the direct identification of the immunopeptidome in different tissues and cell types in different physiological and pathological states, for example, solid tumors or virally infected cells. Despite its advantages, it is still an experimentally and computationally challenging technique with different aspects that need to be considered before planning an MS-immunopeptidomics experiment, while conducting the experiment and with analyzing and interpreting the results. Hence, we aim in this chapter to provide an overview of this method and discuss different practical considerations at different stages starting from sample collection until data analysis. These points should aid different groups aiming at utilizing MS-immunopeptidomics, as well as, identifying future research directions to improve the method.
    Mesh-Begriff(e) Humans ; Histocompatibility Antigens Class I ; Peptides/chemistry ; HLA Antigens ; Histocompatibility Antigens Class II ; Mass Spectrometry/methods
    Chemische Substanzen Histocompatibility Antigens Class I ; Peptides ; HLA Antigens ; Histocompatibility Antigens Class II
    Sprache Englisch
    Erscheinungsdatum 2024-03-28
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-3646-6_23
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Update: Zivil-militärische Zusammenarbeit in chirurgischen Fachgesellschaften (CAMIN und EKTC)

    Güsgen, C / Franke, A

    Wehrmedizinische Monatsschrift

    2023  Band 67, Heft 5, Seite(n) 216

    Sprache Deutsch
    Dokumenttyp Artikel
    ZDB-ID 506502-1
    ISSN 0043-2156
    Datenquelle Current Contents Medizin

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  6. Buch: Modelle von Gesundheit und Krankheit

    Franke, Alexa

    (Lehrbuch Gesundheitswissenschaften ; Verlag Hans Huber, Programmbereich Gesundheit)

    2006  

    Verfasserangabe Alexa Franke
    Serientitel Lehrbuch Gesundheitswissenschaften
    Verlag Hans Huber, Programmbereich Gesundheit
    Schlagwörter Gesundheit ; Krankheit
    Schlagwörter Erkrankung ; Krankheitszustand ; Krankheiten ; Morbus ; Nosos ; Pathos ; Gesundheitsstatus ; Gesundheitszustand
    Sprache Deutsch
    Umfang 231 S. : graph. Darst.
    Ausgabenhinweis 1. Aufl.
    Verlag Huber
    Erscheinungsort Bern
    Erscheinungsland Schweiz
    Dokumenttyp Buch
    HBZ-ID HT014774480
    ISBN 978-3-456-84353-7 ; 3-456-84353-4
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  7. Buch ; Dissertation / Habilitation: Die Rolle von BMP-4 in der Entwicklung chromaffiner Zellen

    Franke, Aylin

    2005  

    Verfasserangabe vorgelegt von Aylin Franke
    Sprache Deutsch
    Umfang III, 82 Bl. : Ill., graph. Darst.
    Erscheinungsland Deutschland
    Dokumenttyp Buch ; Dissertation / Habilitation
    Dissertation / Habilitation Heidelberg, Univ., Diss., 2005
    HBZ-ID HT014964881
    Datenquelle Katalog ZB MED Medizin, Gesundheit

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  8. Artikel ; Online: AI revolution in healthcare and medicine and the (re-)emergence of inequalities and disadvantages for ageing population.

    Stypińska, Justyna / Franke, Annette

    Frontiers in sociology

    2023  Band 7, Seite(n) 1038854

    Abstract: AI systems in medicine and healthcare are being extensively explored in prevention, diagnosis, novel drug designs and after-care. The application of AI technology in healthcare systems promises impressive outcomes such as equalising healthcare, reducing ... ...

    Abstract AI systems in medicine and healthcare are being extensively explored in prevention, diagnosis, novel drug designs and after-care. The application of AI technology in healthcare systems promises impressive outcomes such as equalising healthcare, reducing mortality rate and human error, reducing medical costs, as well as reducing reliance on social services. In the light of the WHO "Decade of Healthy Ageing", AI applications are designed as digital innovations to support the quality of life for older persons. However, the emergence of evidence of different types of algorithmic bias in AI applications, ageism in the use of digital devices and platforms, as well as age bias in digital data suggests that the use of AI might have discriminatory effects on older population or even cause harm. This paper addresses the issue of age biases and age discrimination in AI applications in medicine and healthcare systems and try to identify main challenges in this area. It will reflect on the potential of AI applications to amplify the already existing health inequalities by discussing two levels where potential negative impact of AI on age inequalities might be observed. Firstly, we will address the technical level of age bias in algorithms and digital datasets (especially health data). Secondly, we will discuss the potential disparate outcomes of automatic decision-making systems (ADMs) used in healthcare on the older population. These examples will demonstrate, although only partially, how AI systems may create new structures of age inequalities and novel dimensions of exclusion in healthcare and medicine.
    Sprache Englisch
    Erscheinungsdatum 2023-01-23
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ISSN 2297-7775
    ISSN (online) 2297-7775
    DOI 10.3389/fsoc.2022.1038854
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Kalkaneoplastie mit Radiofrequenzzementierung nach Ballonaufrichtung.

    Rathjen, J / Völlmecke, M / Bieler, D / Franke, A / Kollig, E

    Unfallchirurgie (Heidelberg, Germany)

    2023  Band 127, Heft 2, Seite(n) 151–159

    Abstract: The standard surgical procedure for complex calcaneal fractures is open reduction, internal reduction and internal stable angle plate osteosynthesis via a lateral approach. More recently, options for minimally invasive and percutaneous surgical ... ...

    Titelübersetzung Calcaneoplasty with radiofrequency cementing following balloon reduction.
    Abstract The standard surgical procedure for complex calcaneal fractures is open reduction, internal reduction and internal stable angle plate osteosynthesis via a lateral approach. More recently, options for minimally invasive and percutaneous surgical strategies have been presented [4, 7]. As a possible procedural alternative for a covered, surgical treatment of calcaneal fractures, calcaneoplasty is discussed and applied in this context [5]. In this case series of five complex calcaneal fractures presented here, a balloon catheter was used for percutaneous reduction to restore the alignment of the calcaneus.This was followed by placement of PMMA cement in radiofrequency application and osteosynthesis using percutaneous cannulated screws. This Vicenti technique allows stable reduction and retention with early partial weight bearing with an overall low complication rate [17].
    Mesh-Begriff(e) Humans ; Treatment Outcome ; Fractures, Bone/surgery ; Fracture Fixation, Internal/adverse effects ; Calcaneus/surgery ; Ankle Injuries ; Foot Injuries
    Sprache Deutsch
    Erscheinungsdatum 2023-10-24
    Erscheinungsland Germany
    Dokumenttyp English Abstract ; Journal Article
    ISSN 2731-703X
    ISSN (online) 2731-703X
    DOI 10.1007/s00113-023-01365-2
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Assessing the impact of climate change on crop production in southern Africa: a review

    Franke, AC

    South African journal of plant and soil =. 2021 Jan. 01, v. 38, no. 1

    2021  

    Abstract: This paper provides a systematic review of studies assessing the impact of climate change on crop yields in southern Africa. Moreover, it synthesises the current knowledge of the impact of elevated ambient CO₂ levels (eCO₂) and temperatures on ... ...

    Abstract This paper provides a systematic review of studies assessing the impact of climate change on crop yields in southern Africa. Moreover, it synthesises the current knowledge of the impact of elevated ambient CO₂ levels (eCO₂) and temperatures on physiological processes, and the application of this knowledge in mechanistic crop models. While eCO₂ evidently has a strong impact on photosynthesis and crop water use, it is uncertain how this will work out for the climatic and crop management conditions prevailing in southern Africa. The impact of heat stress on crop reproductive processes and the process of transpiration cooling mitigating heat stress are poorly represented in models, while both process are relevant given the climatic conditions prevailing in southern Africa. Twenty studies assessing the impact of climate change on future yields of crops, mostly maize, have been retrieved. The results suggest that potato, Bambara groundnut and sugarcane yields may improve. No consistent trends for maize and sorghum could be identified. While yield predictions are obviously context-specific, large uncertainties related to climate predictions and crop models imply results should be treated with caution. Suggestions are made for field experimentation and the improved application of crop models for climate change research in the region.
    Schlagwörter Vigna subterranea ; carbon dioxide ; climate change ; corn ; crop management ; field experimentation ; heat stress ; photosynthesis ; potatoes ; soil ; sugarcane ; systematic review ; transpiration ; Southern Africa
    Sprache Englisch
    Erscheinungsverlauf 2021-0101
    Umfang p. 1-12.
    Erscheinungsort Taylor & Francis
    Dokumenttyp Artikel
    Anmerkung NAL-AP-2-clean
    ZDB-ID 2672837-0
    ISSN 2167-034X ; 0257-1862
    ISSN (online) 2167-034X
    ISSN 0257-1862
    DOI 10.1080/02571862.2020.1844325
    Datenquelle NAL Katalog (AGRICOLA)

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